全文获取类型
收费全文 | 1369篇 |
免费 | 63篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 27篇 |
妇产科学 | 31篇 |
基础医学 | 156篇 |
口腔科学 | 50篇 |
临床医学 | 161篇 |
内科学 | 355篇 |
皮肤病学 | 25篇 |
神经病学 | 155篇 |
特种医学 | 96篇 |
外科学 | 135篇 |
综合类 | 7篇 |
一般理论 | 1篇 |
预防医学 | 78篇 |
眼科学 | 16篇 |
药学 | 62篇 |
中国医学 | 1篇 |
肿瘤学 | 65篇 |
出版年
2023年 | 3篇 |
2022年 | 18篇 |
2021年 | 35篇 |
2020年 | 12篇 |
2019年 | 26篇 |
2018年 | 48篇 |
2017年 | 28篇 |
2016年 | 28篇 |
2015年 | 37篇 |
2014年 | 61篇 |
2013年 | 71篇 |
2012年 | 88篇 |
2011年 | 91篇 |
2010年 | 50篇 |
2009年 | 42篇 |
2008年 | 59篇 |
2007年 | 64篇 |
2006年 | 75篇 |
2005年 | 66篇 |
2004年 | 67篇 |
2003年 | 63篇 |
2002年 | 39篇 |
2001年 | 41篇 |
2000年 | 39篇 |
1999年 | 43篇 |
1998年 | 12篇 |
1997年 | 14篇 |
1996年 | 7篇 |
1995年 | 8篇 |
1994年 | 8篇 |
1992年 | 16篇 |
1991年 | 20篇 |
1990年 | 17篇 |
1989年 | 21篇 |
1988年 | 24篇 |
1987年 | 16篇 |
1986年 | 8篇 |
1985年 | 15篇 |
1984年 | 7篇 |
1982年 | 3篇 |
1981年 | 5篇 |
1979年 | 2篇 |
1978年 | 4篇 |
1976年 | 3篇 |
1975年 | 3篇 |
1971年 | 2篇 |
1970年 | 2篇 |
1968年 | 5篇 |
1967年 | 2篇 |
1966年 | 3篇 |
排序方式: 共有1435条查询结果,搜索用时 31 毫秒
1.
2.
3.
Dalton Pompêo de Pina M.D. 《Aesthetic plastic surgery》1990,14(1):27-33
Recently many mammaplasty techniques have been presented with special attention paid to the resulting scar's size and its position. The surgeon should try to hid the scar, and if the inverted T incision is used, its horizontal branch should be as short as possible and kept in the breast area. Neverthelss, excessive concern about the final scar size should not interfere with the final results of the mammaplasty as far as shape, volume and lasting results are concerned. The author presents his experience in mammaplasty with respect to the volume, the shape, and the scar size interrelationships. 相似文献
4.
F. M. González Valverde F. Mauri Barberá M. Molto Aguado N. Torregrosa A. Hernández Quiles F. Menárguez Pina M. J. Gómez Ramos M. García Real J. A. Barreras Mateos J. L. Vázquez Rojas 《European Surgery》2004,36(4):253-256
Summary BACKGROUND: Endometriosis is a relatively common pathology in women of childbearing age and of low parity but rarely shows
extraperitoneal involvement. The main aim of this paper is to raise the attention of specialists to the necessity of carrying
out penetrating diagnosis of nonspecific extraperitoneal masses occurring in women of reproductive age. METHODS: We performed
a retrospective review of six patients diagnosed with extraperitoneal endometriosis who were treated at the Vega Baja University
Hospital (Spain) during the last 5 years. RESULTS: Surgical treatment had positive results in five patients. The preoperative
diagnosis was correctly made in only two patients. The accurate aetiology of endometriosis remains unknown and diagnosis is
based on clinical and cytopathological findings. CONCLUSIONS: Surgical treatment of extraperitoneal endometriosis is recommended.
However, postoperative follow-up is obligatory and hormonal suppressive therapy may be necessary. Medical treatment with gestagens,
Danazol, or agonists of the gonadotropin-releasing hormone are ineffective in endometriomas which are bigger than 2 cm.
相似文献
5.
Marina Quartu Maria Pina Serra Annalisa Manca Paolo Follesa Rossano Ambu Marina Del Fiacco 《International journal of developmental neuroscience》2003,21(6):309-320
The immunohistochemical occurrence of the high affinity neurotrophin (NT) receptors trkA, trkB, and trkC is shown in the pre-term newborn, infant, and adult human post-mortem cerebellum. Immunoreactive neuronal perikarya and processes were observed in all specimens examined, where they appeared unevenly distributed in the cerebellar cortical layers and deep nuclei, and showed regional differences among cerebellar lobules and folia. The trk receptor-antibodies, tested by Western blot on human cerebellum homogenates, revealed multiple immunoreactive bands for trkA and single bands for trkB and trkC. The results obtained show the tissue localization of the trk receptor-like immunoreactivity in the human cerebellum from prenatal to adult age. The analysis for codistribution of the receptors with the relevant ligand and among the receptors in discrete cortical and deep nuclei tissue fields shows a wide variety of conditions, from a good similarity in terms of type and density of labeled structures, to a lack of correspondence, and suggests the possibility of colocalization of trk receptors with the relevant neurotrophin and among them in the cerebellar cortex. These results sustain the concept that the neurotrophin trophic system participates in the development, differentiation, and maintenance of the human cerebellar connectivity and support the possibility of a multifactorial trophic support for the neurotrophins through target-derived and local mechanisms. 相似文献
6.
F. M. Ulivieri L. P. Piodi G. Marotta D. Marchelli C. Commadini L. Parravicini C. Verdoia P. Gerundini 《Journal of orthopaedics and traumatology》2006,7(4):192-194
Osteoprotegerin (OPG) is a protein that inhibits of osteoclastogenesis. The aim this study was to evaluate the response of
serum OPG levels to neridronate treatment in patients with Paget's disease of bone resistant to previous therapy. Nine patients
(4 men) affected by active Paget’s disease of bone (6 polyostotic, 3 monostotic) not responsive to clodronate were studied.
Serum OPG, osteocalcin, total and bone isoenzyme of alkaline phosphatase (AP and BAP, respectively), and urinary deoxypyridinoline
(DPD) were measured before and 5 months after neridronate treatment (100 mg/day, i.v. for two days). A scintigraphic activity
index (SAI) was also calculated before treatment. Mean baseline OPG levels were within normal values and were not significantly
different 5 months after neridronate treatment. In contrast, there were significant reductions in AP (41.9%, p<0.02) and BAP (38.8%, p<0.04). Serum OPG levels correlated with DPD (r=0.925) and SAI (r=0.689). Although OPG is an important regulator of bone metabolism,
in our series of already treated patients it was not a sensitive marker for diagnosing Paget's disease and for monitoring
the response to pharmacological treatment, whereas AP and BAP confirmed their clinical usefulness. This preliminary study
requires confirmation by a study with a larger population. 相似文献
7.
D.R. Pina S.B. Duarte J. Morceli T. Ghilardi Netto 《Applied radiation and isotopes》2006,64(12):1623-1630
We present the construction of a homogeneous phantom to be used in simulating the scattering and absorption of X-rays by a standard patient chest and skull when irradiated laterally. This phantom consisted of lucite and aluminium plates with their thickness determined by a tomographic exploratory method applied to the anthropomorphic phantom. Using this phantom, an optimized radiographic technique was established for chest and skull of standard sized patient in lateral view. Images generated with this optimized technique demonstrated improved image quality and reduced radiation doses. 相似文献
8.
R E Majocha J M Reno R P Friedland C VanHaight L R Lyle C A Marotta 《Journal of nuclear medicine》1992,33(12):2184-2189
We evaluated the efficacy of murine monoclonal antibodies (Mabs) targeted to beta/A4 amyloid for development of procedures for the in vivo identification of amyloid angiopathy (AA) in Alzheimer's disease (AD). Mabs to beta/A4 amyloid were prepared and screened for effectiveness in visualizing AA and senile plaques in postmortem AD brain sections. They were assessed again after enzymatic cleavage to produce Fab fragments and after labeling with 99mTc using a diamide dimercaptide ligand system. Modified and radiolabeled Fab fragments retained activity and specificity towards amyloid-laden blood vessels and senile plaques. A highly specific murine Mab, 10H3, was identified and characterized that fulfills criteria necessary for the development of a diagnostic imaging agent. Expansion and adaptation of these strategies may provide the methods and materials for the noninvasive analysis of AA in living patients, and permit assessment of the contribution of AA to the clinical and pathological features of AD. 相似文献
9.
10.
1996年我们在意大利全国范围内开展了一次关于急性胰腺炎的调查,并对研究结果进行了计算机统计分析. 相似文献