全文获取类型
收费全文 | 3676篇 |
免费 | 207篇 |
国内免费 | 86篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 221篇 |
妇产科学 | 56篇 |
基础医学 | 406篇 |
口腔科学 | 66篇 |
临床医学 | 402篇 |
内科学 | 825篇 |
皮肤病学 | 141篇 |
神经病学 | 239篇 |
特种医学 | 431篇 |
外科学 | 431篇 |
综合类 | 51篇 |
预防医学 | 208篇 |
眼科学 | 107篇 |
药学 | 187篇 |
2篇 | |
中国医学 | 2篇 |
肿瘤学 | 177篇 |
出版年
2023年 | 11篇 |
2022年 | 20篇 |
2021年 | 41篇 |
2020年 | 27篇 |
2019年 | 55篇 |
2018年 | 77篇 |
2017年 | 53篇 |
2016年 | 56篇 |
2015年 | 79篇 |
2014年 | 76篇 |
2013年 | 130篇 |
2012年 | 113篇 |
2011年 | 146篇 |
2010年 | 160篇 |
2009年 | 143篇 |
2008年 | 148篇 |
2007年 | 176篇 |
2006年 | 130篇 |
2005年 | 163篇 |
2004年 | 99篇 |
2003年 | 109篇 |
2002年 | 106篇 |
2001年 | 98篇 |
2000年 | 111篇 |
1999年 | 93篇 |
1998年 | 144篇 |
1997年 | 168篇 |
1996年 | 154篇 |
1995年 | 124篇 |
1994年 | 121篇 |
1993年 | 101篇 |
1992年 | 58篇 |
1991年 | 55篇 |
1990年 | 65篇 |
1989年 | 73篇 |
1988年 | 66篇 |
1987年 | 54篇 |
1986年 | 67篇 |
1985年 | 59篇 |
1984年 | 29篇 |
1983年 | 25篇 |
1982年 | 26篇 |
1981年 | 31篇 |
1980年 | 26篇 |
1979年 | 6篇 |
1978年 | 11篇 |
1977年 | 20篇 |
1976年 | 29篇 |
1975年 | 16篇 |
1966年 | 5篇 |
排序方式: 共有3969条查询结果,搜索用时 15 毫秒
1.
JM Martín† L Calduch† C Monteagudo‡ I Molina† D Ramón† V Alonso† E Jordᆠ《Journal of the European Academy of Dermatology and Venereology》2006,20(4):428-431
Cutaneous plasmacytosis is a rare disorder characterized by a benign proliferation of mature plasma cells that appears as multiple dark-brown to purplish skin lesions, often associated with polyclonal hypergammaglobulinaemia. We present the case of a 55-year-old Caucasian man who suffered from a cutaneous plasmacytosis associated with two different carcinomas. Cutaneous plasmacytosis seems to be a reactive process because most cases reported are not associated with any apparent underlying disease. Nevertheless, because few reported cases were associated with malignancies, screening of additional neoplasms would be justified. 相似文献
2.
3.
4.
Antonio S. Salinas Sánchez Jesús Cifuentes Tebar Miguel Segura Martín José M. Giménez Bachs María J. Donate Moreno Héctor Pastor Navarro Julio A. Virseda Rodríguez 《American journal of transplantation》2005,5(8):2074-2077
Ureteral herniation is a rare entity. We report the first case of extraperitoneal ureteral herniation in a pediatric en bloc renal graft causing obstructive uropathy. A 70-year-old, obese patient with an en bloc renal transplant was found to have ureterohydronephrosis in the right renal graft on magnetic resonance imaging. Nephrostomy with insertion of a double-J catheter confirmed the presence of a ureteral loop within the inguinal tract. Surgery confirmed herniation of the ureter through the internal inguinal ring, crossing over the spermatic cord. We performed release, resection, ureteral reimplantation and hernioplasty. Four months later, renal function was normal and urinary tract dilation had diminished. This case illustrates an unusual cause of obstructive uropathy in a transplanted kidney. Apart from obesity, two other factors may have contributed to its development: presence of a redundant ureter, and the fact that the ureter had been placed over, rather than under, the spermatic cord. 相似文献
5.
6.
JM Vilanova J Figueras-Aloy J Roselló G Gómez E Gelpí R Jiménez 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(5):588-592
The aim of this study was to evaluate the cerebral synthesis of eicosanoids in the asphyctic newborn and to investigate the relation between the prostanoid profiles in cerebrospinal fluid (CSF) and the appearance and severity of hypoxic-ischaemic encephalopathy (HIE). Levels of 6-keto-PGF 1-α, TXB2 , PGE2 and PGF2-α in CSF were measured in 40 full term newborns during the first day of life. Thirty of these newborns had birth asphyxia and were divided into three groups: 10 without HIE, 12 with mild HIE and 8 with moderate-severe HIE. They were compared to a control group of 10 non-hypoxic newborns. Determinations of the metabolites in CSF were performed by RIA and expressed as pg/ml (mean ± SD). The CSF TXB2 (thromboxane A2 metabolite) in asphyxiated newborns was always higher than in the control group (28.12 ± 10.6), and related to the severity of HIE ( p = 0:005): without HIE (50.84 ± 16.4; p = 0:02), mild HIE (80.65 ± 12.64; p ± 0:01) and moderate-severe HIE (178.14 ± 20.5; p < 0:01). The CSF 6-keto-PGF 1-α (prostacyclin metabolite) in asphyxiated newborns was always higher than in the control group (80.55 ± 12.56), but indirectly related to the severity of HIE: without HIE (240.95 ± 28.12; p < 0:01), mild HIE (183.65 ± 30.1; p < 0:01) and moderate-severe HIE (140.55 ± 25.12; p < 0:01). In the moderate-severe HIE group, the increase in TXB2 was higher than the rise in 6-keto-PGF 1-α . 相似文献
7.
8.
Occurrence of the t(2;5)(p23;q35) in non-Hodgkin's lymphoma 总被引:9,自引:3,他引:6
Weisenburger DD; Gordon BG; Vose JM; Bast MA; Chan WC; Greiner TC; Anderson JR; Sanger WG 《Blood》1996,87(9):3860-3868
Primary CD30(Ki-1)-positive anaplastic large-cell lymphoma (ALCL) is considered by some to be a distinct clinicopathologic entity associated with the t(2;5) (p23;q35). However, the specificity of t(2;5) for ALCL has not been carefully studied. Therefore, we performed a detailed analysis of all cases of ALCL with abnormal cytogenetics results in the Nebraska Lymphoma Study Group registry, as well as all other cases of non-Hodgkin's lymphoma with t(2;5) in the registry. We found the t(2;5) in only five of 10 cases of ALCL, four of whom were young patients. However, we also found the t(2;5) in 11 other cases of nonanaplastic lymphoma, including eight children with typical peripheral T-cell lymphomas of various types. The t(2;5) was also found in three older adults with B-cell lymphomas of various types. Thus, the t(2;5) was not specific for CD30+ ALCL. However, t(2;5) may define a clinicopathologic entity in children and young adults characterized by variable morphologies with a T-cell or indeterminate phenotype, CD30-positivity, nodal disease with frequent extranodal involvement, advanced stage, and an excellent response to therapy, including bone marrow transplantation for relapsed disease. The clinical relevance of the t(2;5) in older patients requires further study. 相似文献
9.
R. Gil-Grande J. M. Aguado C. Pastor M. García-Bravo C. Gómez-Pellico F. Soriano A. R. Noriega 《European journal of clinical microbiology & infectious diseases》1995,14(1):64-67
A patient with culture-negative endocarditis was diagnosed with Q fever endocarditis based on the results of serological tests and positive leukocyte cultures obtained using conventional viral cultures and the shell vial technique. This case report suggests that isolation ofCoxiella burnetii from blood may allow better diagnostic and therapeutical evaluation of patients with Q fever endocarditis. The use of both conventional and shell vial viral cultures is recommended for the isolation ofCoxiella burnetii from the blood of patients with apparently culture-negative endocarditis. 相似文献
10.