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排序方式: 共有1472条查询结果,搜索用时 15 毫秒
1.
Ichiro Yasuda Takuji Iwashita Takaya Ohnishi Tsuyoshi Mukai Masamichi Enya Eiichi Tomita Hisataka Moriwaki 《Digestive endoscopy》2006,18(Z1):S92-S95
Endoscopic nasobiliary drainage (ENBD) is a well established mode of biliary decompression. Although ENBD is certainly an uncomfortable procedure with the potential risk of spontaneous dislocation or removal of the drainage catheter by disoriented patients, it has several advantages over endoscopic biliary drainage (EBD) using an indwelling stent. The current indications for ENBD are: (i) temporary drainage to treat obstructive jaundice and cholangitis caused by malignant or benign biliary stricture; (ii) urgent drainage to treat suppurative cholangitis primarily caused by common bile duct stones; (iii) temporary drainage after stone removal in patients with suspected incomplete clearance and/or with cholangitis; and (iv) biliary leaks that occur primarily after surgery, as well as other indications. Different types of nasobiliary catheters are currently available that have been designed with various diameters, shapes, and materials. However, the current catheters are not considered by most endoscopists to be sufficient. Further improvements are needed to achieve better drainage and better maneuverability. 相似文献
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Matsukawa T.; Hanagata K.; Ozaki M.; Iwashita H.; Koshimizu M.; Kumazawa T. 《British journal of anaesthesia》1997,78(4):396-399
We tested the hypothesis that premedication with i.m. midazolam decreases
core temperature dose-dependently. We studied six male volunteers, in
random order, on 3 days: (1) no midazolam administration (control day), (2)
midazolam 0.025 mg kg-1 i.m., (3) midazolam 0.075 mg kg-1 i.m. On the first
day, subjects were maintained alert during a 30- min control period. On the
second and third days, midazolam 0.025 or 0.075 mg kg-1 was administered
i.m. Core temperatures were measured at the right tympanic membrane. Four
adhesive skin surface probes were fixed on the chest, upper right arm,
lateral calf and thigh. Finger tip perfusion was evaluated using forearm
minus fingertip and calf minus toe, skin surface temperature gradients.
Thirty minutes after midazolam i.m., the level of sedation in the
volunteers was assessed. Peripheral venous blood was obtained immediately
after the assessment of the level of sedation. Tympanic membrane
temperatures after administration of midazolam 0.075 mg kg-1 i.m. were
significantly lower than those on the control and midazolam 0.025 mg kg-1
i.m. days at 20 and 30 min. The decreases in tympanic membrane temperatures
at 30 min after midazolam i.m. became larger as the volunteers were more
deeply sedated. i.m. midazolam produced a concentration-dependent decrease
in tympanic membrane temperature at 30 min after midazolam 0.025 and 0.075
mg kg-1 i.m. We conclude that midazolam impaired tonic thermoregulatory
vasoconstriction, allowing core-to-peripheral heat redistribution in a
dose-dependent manner after i.m. administration.
相似文献
4.
Tomomi Iwashita Kazuo Kitazawa Jun-Ichi Koyama Hisashi Nagashima Toru Koyama Yuichiro Tanaka Kazuhiro Hongo Hiroshi Okudera Kazufumi Okamoto 《Journal of clinical neuroscience》2007,14(1):68-71
A patient with cerebral deep sinus thrombosis, which was not diagnosed on the first examination, is reported. A 46-year-old woman presented with headache and vomiting. Neurological examination and a brain computed tomography (CT) scan showed no obvious abnormal findings. The patient suffered disturbed consciousness on the day after the examination, and was admitted to our emergency centre. A CT scan and magnetic resonance imaging revealed an ischaemic lesion in the left basal ganglia, suggesting deep sinus occlusion. Anticoagulant therapy was administered. One day after admission, a CT scan showed a haematoma and severe brain swelling in the same region. Cerebral angiography demonstrated a straight sinus occlusion. Intracranial pressure was not controlled with hypothermia, and the patient died 25 days after admission. Review of the initial CT scan revealed subtle, early findings of deep venous thrombosis that were missed on first examination. 相似文献
5.
Mitsutoshi Satoh Keisuke Enomoto Katsuo Koike 《The Journal of pharmacy and pharmacology》2001,53(1):103-108
The antagonistic effects of MDL73005EF and tamsulosin and partial agonists clonidine and tizanidine at rat thoracic aorta and rabbit iliac artery alpha1-adrenoceptors were investigated in this study. Selective alpha1-adrenoceptor antagonists MDL73005EF and tamsulosin dose-dependently shifted the concentration-response curves for noradrenaline to the right. Schild plots of the results obtained from the inhibition by MDL73005EF (pA2 8.30 +/- 0.04) and tamsulosin (pA2 10.51 +/- 0.06) of noradrenaline yielded a straight line with a slope of unity in rat thoracic aorta. The slopes of Schild plots obtained from the inhibition by MDL73005EF and tamsulosin of noradrenaline were significantly different from unity in rabbit iliac artery. Schild plots of the results obtained from the inhibition by clonidine and tizanidine of noradrenaline yielded a straight line with a slope of unity in rat thoracic aorta (pA2 7.08 +/- 0.04 and 7.32 +/- 0.04, respectively). These results suggest that alpha1D-adrenoceptors play a significant role in the alpha1-adrenoceptor-agonist-induced contraction of rat thoracic aorta and rabbit iliac artery, and that clonidine and tizanidine interact with the alpha1D-adrenoceptor subtype as competitive antagonists in rat thoracic aorta. 相似文献
6.
Toshimitsu Iwashita Munetomo Enjoji 《Virchows Archiv : an international journal of pathology》1987,411(4):305-309
Summary A clinicopathological and immunohistochemical study was done on 23 plexiform (multinodular) neurilemomas excised from 20 Japanese. Ages of the subjects ranged from 2 years to 69 years with a mean age of 30 years. The tumours occurred most often on the trunk (14), and were located commonly in the dermis and subcutis (19). Three lesions apparently originated from the peripheral nerve trunks. Multiple tumours were observed in six instances, and two were associated with von Recklinghausen's disease. Microscopically, they appeared as multinodular growths, most nodules were moderately cellular, and both Antoni A and B patterns were distinct in 10 tumours. Obvious Verocay bodies were noted in seven tumours and abortive ones in five. Immunohistochemical reactivity to S-100 protein was demonstrated in both nuclei and cytoplasm of almost all tumour cells of all lesions examined. Recurrences are nil among the 4 patients who could be followed. Correlations with trauma and with von Recklinghausen's disease are briefly discussed. 相似文献
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Yoshinao Oda Masazumi Tsuneyoshi Hiroshi Hashimoto Toshimitsu Iwashita Masahiro Ushijima Sachio Masuda Yukihide Iwamoto Yoichi Sugioka 《Virchows Archiv : an international journal of pathology》1993,423(1):65-69
Primary rhabdomyosarcoma of bone is exceedingly rare. We present a case of rhabdomyosarcoma of the iliac bone in a 32-year-old male. Histologically, the tumour consisted mainly of a uniform proliferation of elongated spindle cells arranged in a herring bone pattern, simulating fibrosarcoma. Focally there was a conventional embryonal pattern with scattered rhabdomyoblasts possessing an eosinophilic cytoplasm. Immunohistochemical studies disclosed expression of muscle markers such as desmin and muscle-specific actin, in both the embryonal and spindle-cell areas and myoglobin only in the embryonal areas. Such histological features are unusual for classical embryonal rhabdomyosarcoma. The anatomical site and age of the patient are also atypical. 相似文献
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