品管圈活动在ICU护生临床实习带教中的应用

目的 探讨品管圈活动在ICU护生临床实习带教中的应用效果。方法 选取2014年7月-2015年2月在ICU实习的48名护生为对照组,采用传统方法进行临床实习带教。选取2015年7月-2016年2月在ICU实习的52名护生为观察组,将品管圈活动运用到临床实习带教中。比较2组护生的理论、技能操作考核成绩及对带教老师的满意度。结果 观察组的理论与操作考核成绩及对带教教师的满意度测评分均高于对照组。结论 将品管圈活动运用到ICU护生临床实习带教中,有效提升了实习护生的理论与技能操作成绩及临床带教老师的专业素质。     

载脂蛋白E基因多态性与原发性高尿酸血症相关性研究

目的：探讨维吾尔族与汉族载脂蛋白E基因多态性与原发性高尿酸血症的相关性。方法：收集2006年1～12月在新疆医科大学附属中医医院和乌鲁木齐市宝科达医院健康体检的670人血标本,检测血尿酸、血液生化指标以及ApoE基因型。结果：新疆维吾尔族和汉族ApoE基因型分布差异有统计学意义（P〈0.05）,汉族高尿酸组和正常组ApoE基因型分布总体差异有统计学意义（P〈0.05）,而维吾尔族总体差异无统计学意义（P〉0.05）。汉族和维吾尔族ApoE基因型中E3/3占主导,汉族E2/2〉E4/4,而维吾尔族正好相反。与正常组相比,高尿酸组ApoEε2等位基因频率降低,而ε4频率升高,ε4等位基因可能是原发性高尿酸血症的危险因素。两个民族高尿酸组不同等位基因血尿酸（SUA）和除高密度脂蛋白-胆固醇（HDL-C）外的各生化指标均高于正常组,而且两个民族高尿酸组和正常组尿酸和血脂代谢指标水平在ApoE等位基因ε2、ε3、ε4型中也有一定的差别。结论：ApoEε4等位基因可能是汉族和维吾尔族原发性高尿酸血症的遗传易感基因,但仍然表现出民族的差异。     

新疆126例孕产妇死亡评审结果分析

目的 通过孕产妇死亡评审及时发现和掌握各个环节中存在的问题,提出针对性的干预措施,为降低孕产妇死亡率提供决策依据.方法 对自治区2010年10月至2011年9月死亡的上报材料完整的126例孕产妇死亡材料,根据<新疆维吾尔自治区级孕产妇死亡评审管理办法>规定,采用WHO"十二格表"评审方法进行评审分析.结果 前5位死因依次为产科出血(34.92%)、妊娠期高血压疾病(27.78%)、妊娠合并心脏病(11.11%)、静脉血栓及肺栓塞症(5.56%)、甲型H1N1流感(3.17%);前5位主要死因构成占全部死亡的82.54%.直接产科原因与间接产科原因之比为1.6:1;可以避免的死亡占92.06%,不可避免的死亡占7.94%.结论 地、县、乡三级医疗保健机构缺乏有产科资质的医护人员,现有人员素质偏低;应进一步加强孕产妇急救绿色通道和急救中心建设,保证急危重症孕产妇的有效转诊;乡镇卫生院硬件设施缺乏,孕产妇产前保健质量低下;重视和发挥健康教育的先导作用,提高妇女自我保护意识;计划外生育对孕产妇死亡影响不可忽视.     

Bacteriological study of bottled drinking water marketed in Mangalore

Bottled water is generally accepted as safe for consumption. However, its potability is uncertain. Ninety samples of Six national and 3 local brands marketed in Mangalore City were studied. Seven of these were ISI certified. Bacteriological analysis of these samples were carried out for viable count, presumtive coliform count by multiple tube method, confirmed Esch. coli count by Eijkman test and specific intestinal pathogens, such as Salmonella, Shigella and Vibrios. Thirty out of 90 samples though free from coliforms, had viable count much higher than specified by Bureau of Indian Standard. Three samples of one of the brands which is ISI not certified had Esch. coli with most probable number 18/100 ml and Salmonella typhimurium. It is concluded that bottled water can not be taken for granted to be safe.     

新疆农村3县婴幼儿贫血发生率及影响因素分析

目的 调查新疆吉木乃县、乌什县和巴里坤县婴幼儿贫血发生率及其影响因素,了解基线资料,提出预防策略和措施.方法 根据全国“消除婴幼儿贫血行动”项目基线调查,采用多阶段分层整群随机抽样方法,按各县2个样本乡(镇),选择吉木乃县、乌什县和巴里坤县641名6～ 36月龄婴幼儿及其看护人为调查对象,通过问卷调查和采血了解婴幼儿贫血发生率及其影响因素.结果 3县婴幼儿贫血发生率为52.11％ (334/641).其中6～11月龄婴幼儿的贫血发生率最高,为58.62％ (85/145).3县婴幼儿不同年龄段贫血发生率的差异无统计学意义(P＞0.05).女性婴幼儿贫血发生率略高于男性婴幼儿,差异无统计学意义(P＞0.05).早产、看护人文化程度和方便食品的添加是贫血的危险因素(OR值分别为2.51、1.27和2.11,均P＜0.05).主要监护人对婴幼儿贫血相关知识了解的很少.结论 新疆农村婴幼儿贫血发生率较高,应通过对贫困地区婴幼儿营养干预和提高家长科学育儿水平,降低婴幼儿贫血发生率.     

人工智能辅助诊断系统对肺腺癌亚型的预测价值

 目的 探讨人工智能(artificial intelligence, AI)辅助诊断系统分析磨玻璃结节(ground glass nodule, GGN)的CT定量参数对肺腺癌亚型的预测价值。方法 回顾性选取新疆医科大学第一附属医院昌吉分院2017-01至2021-12经手术病理证实的肺内磨玻璃结节患者97例,根据病灶的浸润程度分为非浸润组(44例)和浸润组(53例)。提取GGN的AI定量参数特征,采用独立样本t检验比较两组间统计学差异;预测GGN病灶侵袭程度用受试者特征曲线(receiver operator characteristic curve, ROC)和二元Logistics回归模型评估AI定量参数的诊断效能。结果 非浸润组和浸润组比较,GGN最大径、体积、平均CT值和实性成分所占比均有差异(P<0.05),CT定量参数的预测价值从高到低依次为实性成分占比、平均CT值、最大径、体积。Logistics回归分析显示实性成分占比(OR=1.262,P<0.05)及平均CT值(OR=1.010,P<0.05)在预测GGN侵袭中的诊断价值较高,可作为独立预测因子,诊断阈值为1.085%和-557.00 HU。结论 AI可通过分析GGN的实性成分占比和平均CT值对肺腺癌亚型做出有效预判。     

Influence of gamma-ray irradiation and post-annealing studies on pentacene films: the anisotropic effects on structural and electronic properties

In this work, γ-ray irradiation effects on pentacene thin films are investigated in terms of the change in the crystallinity, and electronic structure as well as chemical states of the film. The pentacene films are γ-irradiated up to 3 kGy and then characterized using synchrotron X-ray diffraction, near edge X-ray absorption fine structure (NEXAFS) and X-ray photoelectron spectroscopy. We found that γ-ray irradiation creates defects, resulting in a decrease of X-ray diffraction intensity both in the plane normal and in-plane directions. From angle dependent NEXAFS; the transition of C 1s to π* orbital for irradiated samples increases; suggesting that the unoccupied π* states enhance due to defects or radical formation in pentacene thin films. Additionally, the in-plane resistivity shows a decreasing trend of resistance after irradiation. This trend of increase in conductivity is also consistent with C 1s to π transition, which manifests the increase in carrier concentration. Hall effect measurements further confirmed the increase in carrier concentration as a function of dose; however, the mobility of the sample decreases as the dose rate increases due to the defects created. By post-irradiation annealing, the thin film phase diffraction intensity can be recovered. Altogether, the anisotropic studies on pentacene films disclosed that the irradiation leads to defect formation along in-plane and plane normal directions. Overall, these results suggest that pentacene is one of the robust organic electronic materials; whose structure remains mostly intact even after irradiation up to a dose of 3 kGy.

In this work, γ-ray irradiation effects on pentacene thin films are investigated in terms of the change in the crystallinity, and electronic structure as well as chemical states of the film.     

冬羔生产技术研究

本文对天山北坡中段牧民定居点暖季放牧＋冷季舍饲模式下的冬羔生产过程中母羊妊娠、产羔、营养补饲、冬羔生长发育及经济效益进行了生产试验研究。结果表明：①冬羔的繁殖成活率和初生重（Ｐ＜０．０１）分别比春羔高１３．４％、２２．８％。②冬羔平均断奶体重（Ｐ＜０．０１）和６月龄平均体重（Ｐ＜０．０５）分别比春羔高２８．７％、１０．９％,冬羔１０月龄平均体重达到５０ｋｇ以上。③每只冬羔创造的经济价值比春羔高 ３４． １％。     

原发性醛固酮增多症与原发性高血压的糖脂代谢比较

目的:比较原发性醛固酮增多症与原发性高血压的糖脂代谢特征。方法:431例已确诊的原发性醛固酮增多症(PA)患者,其中256例行肾上腺静脉取血,分为原醛单侧组(LPA,n=147)、原醛双侧组(NLPA,n=109)。同时入选与性别、年龄、及高血压病程相匹配的同期住院原发性高血压(EH)患者200例为对照组。收集各组的临床资料和生化指标,计算PA检出率并分析糖脂代谢特点。结果:(1)PA检出率为10.54%(431/4100);(2)体重指数、腰围PA组较EH组高;(3)血三酰甘油LPA组高于NLPA组和EH组,高密度脂蛋白NLPA较EH组低;(4)血糖水平、血胰岛素各点及胰岛素抵抗指数均PA组高于EH组,且NLPA组高于LPA组;(5)体重指数可增加LPA组危险性(OR值=2.24,P=0.024);(6)三酰甘油与尿醛固酮呈显著正相关,体重指数与卧位醛固酮水平呈正相关,各点胰岛素水平和胰岛素抵抗指数均与醛固酮水平和尿醛固酮呈显著正相关。结论:与EH患者相比,PA糖脂代谢异常程度重,其中LPA脂代谢以及NLPA组糖代谢异常更为严重。     

碘仿生物止血海绵预防下颌阻生智齿拔除术后干槽症的疗效观察

目的观察碘仿生物止血海绵在预防下颌阻生智齿拔除术后干槽症的临床效果。方法选择需要拔除的下颌阻生智齿300颗,随机分为2组,实验组拔牙创内放置碘仿生物止血海绵,对照组拔牙创内不放入任何药物。结果实验组干槽症发生率0.67%,对照组干槽症发生率6%。两组发生率经统计学分析有显著性差异（P〈0.05）。结论碘仿生物止血海绵能有效预防下颌阻生智齿拔除术后干槽症的发生。