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Validity/Reliability of PHQ-9 and PHQ-2 Depression Scales Among Adults Living with HIV/AIDS in Western Kenya 总被引:1,自引:1,他引:0
Patrick O. Monahan PhD Enbal Shacham PhD Michael Reece PhD MPH Kurt Kroenke MD Willis Owino Ong’or MMEd MPH Otieno Omollo MBChB MMed Violet Naanyu Yebei MA Claris Ojwang 《Journal of general internal medicine》2009,24(2):189-197
Background Depression greatly burdens sub-Saharan Africa, especially populations living with HIV/AIDS, for whom few validated depression
scales exist. Patient Health Questionnaire-9 (PHQ-9), a brief dual-purpose instrument yielding DSM-IV diagnoses and severity,
and PHQ-2, an ultra-brief screening tool, offer advantages in resource-constrained settings.
Objective To assess the validity/reliability of PHQ-9 and PHQ-2.
Design Observational, two occasions 7 days apart.
Participants A total of 347 patients attending psychosocial support groups.
Measurements Demographics, PHQ-9, PHQ-2, general health perception rating and CD4 count.
Results Rates for PHQ-9 DSM-IV major depressive disorder (MDD), other depressive disorder (ODD) and any depressive disorder were 13%,
21% and 34%. Depression was associated with female gender, but not CD4. Construct validity was supported by: (1) a strong
association between PHQ-9 and general health rating, (2) a single major factor with loadings exceeding 0.50, (3) item-total
correlations exceeding 0.37 and (4) a pattern of item means similar to US validation studies. Four focus groups indicated
culturally relevant content validity and minor modifications to the PHQ-9 instructions. Coefficient alpha was 0.78. Test-retest
reliability was acceptable: (1) intraclass correlation 0.59 for PHQ-9 total score, (2) kappas 0.24, 0.25 and 0.38 for PHQ-9
MDD, ODD and any depressive disorder and (3) weighted kappa 0.53 for PHQ-9 depression severity categories. PHQ-2 ≥3 demonstrated
high sensitivity (85%) and specificity (95%) for diagnosing any PHQ-9 depressive disorder (AUC, 0.97), and 91% and 77%, respectively,
for diagnosing PHQ-9 MDD (AUC, 0.91). Psychometrics were also good within four gender/age (18–35, 36–61) subgroups.
Conclusions PHQ-9 and PHQ-2 appear valid/reliable for assessing DSM-IV depressive disorders and depression severity among adults living
with HIV/AIDS in western Kenya. 相似文献
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Repeat prescribing of medications: A system‐centred risk management model for primary care organisations 下载免费PDF全文
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Cindy L. Amundsen MD Margaret E. Helmuth MA Abigail R. Smith PhD John O.L. DeLancey MD Catherine S. Bradley MD MSCE Kathryn E. Flynn PhD Kimberly S. Kenton MD MS H. Henry Lai MD David Cella PhD James W. Griffith PhD Victor P. Andreev PhD DSc J. Eric Jelovsek MD MMEd Alice B. Liu MPH Ziya Kirkali MD Claire C. Yang MD the LURN Study Group 《Neurourology and urodynamics》2020,39(1):393-402