全文获取类型
收费全文 | 8442篇 |
免费 | 224篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 198篇 |
儿科学 | 745篇 |
妇产科学 | 386篇 |
基础医学 | 758篇 |
口腔科学 | 228篇 |
临床医学 | 725篇 |
内科学 | 1686篇 |
皮肤病学 | 413篇 |
神经病学 | 315篇 |
特种医学 | 179篇 |
外科学 | 1255篇 |
综合类 | 314篇 |
一般理论 | 6篇 |
预防医学 | 730篇 |
眼科学 | 178篇 |
药学 | 431篇 |
1篇 | |
中国医学 | 13篇 |
肿瘤学 | 145篇 |
出版年
2017年 | 49篇 |
2016年 | 33篇 |
2015年 | 69篇 |
2014年 | 66篇 |
2013年 | 100篇 |
2012年 | 109篇 |
2011年 | 126篇 |
2010年 | 116篇 |
2009年 | 157篇 |
2008年 | 82篇 |
2007年 | 88篇 |
2006年 | 111篇 |
2005年 | 64篇 |
2003年 | 31篇 |
2001年 | 46篇 |
2000年 | 31篇 |
1999年 | 65篇 |
1998年 | 155篇 |
1997年 | 201篇 |
1996年 | 216篇 |
1995年 | 166篇 |
1994年 | 166篇 |
1993年 | 166篇 |
1992年 | 95篇 |
1991年 | 100篇 |
1990年 | 102篇 |
1989年 | 108篇 |
1988年 | 94篇 |
1987年 | 100篇 |
1986年 | 84篇 |
1985年 | 64篇 |
1984年 | 65篇 |
1983年 | 51篇 |
1982年 | 52篇 |
1981年 | 60篇 |
1980年 | 47篇 |
1979年 | 36篇 |
1978年 | 31篇 |
1977年 | 46篇 |
1976年 | 37篇 |
1959年 | 349篇 |
1958年 | 764篇 |
1957年 | 877篇 |
1956年 | 780篇 |
1955年 | 812篇 |
1954年 | 788篇 |
1953年 | 39篇 |
1952年 | 35篇 |
1949年 | 182篇 |
1948年 | 128篇 |
排序方式: 共有8706条查询结果,搜索用时 62 毫秒
1.
GIUSEPPE BORIANI MAURO BIFFI MAURIZIO RUSSO† MAURIZIO LUNATI‡ GIANLUCA BOTTO¶ ALESSANDRO PROCLEMER§ GIUSEPPE VERGARA WERNER RAHUE†† CRISTIAN MARTIGNANI RENATO RICCI† MASSIMO SANTINI† On Behalf of the SEARCH MI Registry Italian Investigators 《Pacing and clinical electrophysiology : PACE》2006,29(S2):S29-S34
Background: Large randomized trials show that in appropriately selected patients with left ventricular dysfunction, implantable cardioverter-defibrillators (ICDs) can improve overall survival at 2–5 years. Since direct implementation of the criteria used in the MADIT II and SCD-HeFT will lead to a marked rise in ICD implants, there is a growing fear that increased use of ICDs may cause a dramatic burden to health care systems. The ICD has traditionally been seen as an expensive form of treatment, which is difficult to accept at the first look. This is mainly due to the nonlinear character of the ICD investment, characterized by high initial expenditure, followed by a deferred pay-off in terms of clinical benefits. Cost-effectiveness analysis may help provide a different perspective on the problem of ICD cost, as may estimation of the daily cost of ICD treatment, assuming a time horizon of 5–7 years—a particularly interesting subject for further registry studies.
Methods and Results: Based on real expenditure data from 2002 to 2005, as recorded in the Search-MI Registry-Italian Sub-study of patients implanted on MADIT II indications, we estimated the daily costs associated with the device and leads. Over a 5–7 year time horizon, the average daily cost was estimated to be €4.60–€6.70. Translation of these figures into U.S. market conditions suggests a daily cost of around $7.90–$11.40.
Conclusions: These findings appear useful to help evaluate the affordability of ICD in comparison with other therapeutic options in a context of limited available economic resources. 相似文献
Methods and Results: Based on real expenditure data from 2002 to 2005, as recorded in the Search-MI Registry-Italian Sub-study of patients implanted on MADIT II indications, we estimated the daily costs associated with the device and leads. Over a 5–7 year time horizon, the average daily cost was estimated to be €4.60–€6.70. Translation of these figures into U.S. market conditions suggests a daily cost of around $7.90–$11.40.
Conclusions: These findings appear useful to help evaluate the affordability of ICD in comparison with other therapeutic options in a context of limited available economic resources. 相似文献
2.
3.
Restriction fragment length polymorphism of human mitochondrial DNA in a sample population from Apulia (Southern Italy) 总被引:8,自引:1,他引:7
Restriction fragment length polymorphism (RFLP) of human mitochondrial DNA was analysed in a sample of 87 subjects from Apulia (South Italy) by the restriction enzymes Hpa I, Bam HI, Hae II, Msp I, Ava II, and Hinc II using total blood cell DNA probed by human mtDNA from placenta. Five BamHI morphs were observed, two of which are new ( Bam HI-4 and -5), as well as one new Ava II morph ( Ava II-28). The association Bam HI-4/ Ava II-28 enables us to demonstrate for the first time two polymorphic Bam HI sites present together in the same mtDNA molecule. In agreement with historical data the Apulian sample has been shown to be the most heterogeneous Italian population so far tested. 相似文献
4.
GIUSEPPE PERSEO MAURO GIGLI ROBERTO DE CASTIGLIONE 《Chemical biology & drug design》1987,29(4):478-485
The synthesis of TPH-13 (Glp-Glu-Lys-Pro-Tyr-Trp-Pro-Pro-Pro-Ile-Tyr-Pro-Met-OH), a tridecapeptide isolated from the skin of the South American frog Phyllomedusa rohdei, is described and alternative approaches are discussed. 相似文献
5.
Intratemporal vascular tumors: detection with CT and MR imaging 总被引:1,自引:0,他引:1
Lo WW; Shelton C; Waluch V; Solti-Bohman LG; Carberry JN; Brackmann DE; Wade CT 《Radiology》1989,171(2):445-448
The diagnostic contributions of computed tomography (CT) and magnetic resonance (MR) imaging were compared in 12 patients with benign intratemporal vascular tumors (hemangioma or vascular malformation). The tumors included six in the internal acoustic canal and six in the geniculate ganglion region. Clinical and histologic correlations were made. Two of the six patients with tumors in the internal acoustic canal underwent CT, and both required gas cisternography to show the tumor. Five patients in that group underwent MR imaging, and all five studies showed the tumor. All six patients with geniculate ganglion tumors underwent CT. Results in one study were questionable, and five showed the tumor. Five patients in this group underwent MR imaging, but the MR findings were positive in only two cases. MR imaging should therefore be performed before CT in the evaluation of facial nerve dysfunction, as it demonstrated all tumors in the internal acoustic canal and some in the geniculate ganglion region. If MR findings are negative, CT should then be performed to rule out a possible geniculate ganglion lesion. 相似文献
6.
LEON FLICKER 《Internal medicine journal》1989,19(4):400-406
With the growing advent of rehabilitation units designed particularly for the needs of the stroke patient, a need has arisen for the evaluation of these units. In particular, several questions have to be asked 相似文献
7.
L. TIMMER-DE MIK M.D. D.M. BROEKHUIJSEN-VAN HENTEN M.D. † J.M. OLDHOFF M.D. PH.D. D.B. DE GEER M.D. ‡ V. SIGURDSSON M.D. PH.D. S.G.M.A. PASMANS M.D. PH.D. 《Pediatric dermatology》2009,26(3):358-360
Abstract: In Sweet's syndrome, the essential features are the characteristic morphology of the lesions, their histologic appearance, the dramatic response to corticosteroids and the absence of scarring. We report an 8-month-old infant in whom Sweet's syndrome was diagnosed and who developed acquired cutis laxa in the skin lesions. 相似文献
8.
9.
10.