全文获取类型
收费全文 | 11006篇 |
免费 | 704篇 |
国内免费 | 47篇 |
专业分类
耳鼻咽喉 | 141篇 |
儿科学 | 235篇 |
妇产科学 | 203篇 |
基础医学 | 1649篇 |
口腔科学 | 1259篇 |
临床医学 | 738篇 |
内科学 | 2269篇 |
皮肤病学 | 267篇 |
神经病学 | 634篇 |
特种医学 | 236篇 |
外科学 | 1162篇 |
综合类 | 66篇 |
一般理论 | 4篇 |
预防医学 | 1214篇 |
眼科学 | 313篇 |
药学 | 779篇 |
中国医学 | 115篇 |
肿瘤学 | 473篇 |
出版年
2023年 | 97篇 |
2022年 | 210篇 |
2021年 | 432篇 |
2020年 | 279篇 |
2019年 | 381篇 |
2018年 | 450篇 |
2017年 | 291篇 |
2016年 | 340篇 |
2015年 | 423篇 |
2014年 | 538篇 |
2013年 | 607篇 |
2012年 | 970篇 |
2011年 | 990篇 |
2010年 | 507篇 |
2009年 | 419篇 |
2008年 | 668篇 |
2007年 | 618篇 |
2006年 | 540篇 |
2005年 | 471篇 |
2004年 | 481篇 |
2003年 | 361篇 |
2002年 | 301篇 |
2001年 | 199篇 |
2000年 | 161篇 |
1999年 | 159篇 |
1998年 | 69篇 |
1997年 | 36篇 |
1996年 | 27篇 |
1995年 | 25篇 |
1994年 | 17篇 |
1993年 | 15篇 |
1992年 | 53篇 |
1991年 | 54篇 |
1990年 | 52篇 |
1989年 | 46篇 |
1988年 | 52篇 |
1987年 | 56篇 |
1986年 | 46篇 |
1985年 | 38篇 |
1984年 | 20篇 |
1983年 | 29篇 |
1979年 | 13篇 |
1976年 | 13篇 |
1975年 | 13篇 |
1974年 | 15篇 |
1973年 | 19篇 |
1971年 | 12篇 |
1969年 | 21篇 |
1968年 | 13篇 |
1966年 | 13篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
The Transient Receptor Potential Vanilloid 1 Antagonist Capsazepine Improves the Impaired Lung Mechanics during Endotoxemia 下载免费PDF全文
Layla D. M. Cabral Alexandre Giusti‐Paiva 《Basic & clinical pharmacology & toxicology》2016,119(5):421-427
Acute lung injury (ALI) caused by systemic inflammatory response remains a leading cause of morbidity and mortality in critically ill patients. Management of patients with sepsis is largely limited to supportive therapies, reflecting an incomplete understanding of the underlying pathophysiology. Furthermore, there have been limited advances in the treatments for ALI. In this study, lung function and a histological analysis were performed to evaluate the impact of transient receptor potential vanilloid‐1 receptor (TRPV1) antagonist (capsazepine; CPZ) on the lipopolysaccharide (LPS)‐induced lung injury in mice. For this, adult mice pre‐treated with CPZ or vehicle received intraperitoneal injections of LPS or saline and 24 hr after, the mice were anaesthetized, and lung mechanics was evaluated. The LPS‐challenged mice exhibited substantial mechanical impairment, characterized by increases in respiratory system resistance, respiratory system elastance, tissue damping and tissue elastance. The pre‐treatment with CPZ prevented the increase in respiratory system resistance and decreased the increase in tissue damping during endotoxemia. In addition, mice pre‐treated with CPZ had an attenuated lung injury evidenced by reduction on collapsed area of the lung parenchyma induced by LPS. This suggests that the TRPV1 antagonist capsazepine has a protective effect on lung mechanics in ALI during endotoxemia and that it may be a target for enhanced therapeutic efficacy in ALI. 相似文献
3.
4.
5.
6.
7.
Caio Henrique de Carvalho Assuno Júlio Csar Trabanco Raquel Fornaziero Gomes Renata Rodrigues Moreira Alessandra Giannella Samelli 《La Medicina del lavoro》2019,110(4):304
Objective:The present study evaluates a training program for fitting different hearing protection devices (HPDs) based on personal attenuation rating (PAR) before, immediately after, and six months after training.Methods:A total of 67 workers from a public university in the city of São Paulo, Brazil, were invited to participate in the measurement of PARs for foam and silicone protectors through the 3M™ E-A-Rfit Validation System. Two evaluations were performed for each protector at each sampling date: one after reading printed material (the package instructions) and another after being trained by an audiologist. The same procedures were repeated after six months. The final sample consisted of 30 individuals. ANOVA was used for statistical analysis.Results:Larger PAR values were observed after training by the audiologist, and smaller values were observed after six months. Then, after re-training, the values increased again. There were no statistically significant differences in PAR among the HPDs tested. Even after the two training sessions, 23 to 27% of the subjects did not obtain adequate PAR values.Conclusion:These findings emphasize the need for continual worker training in the correct fit of earplug HPDs and the importance of longitudinal PAR monitoring. In addition, some workers, despite the training provided, did not adapt to the HPDs used. Therefore, it is essential that other protection methods and/or other HPD types are made available to these individuals.Key words: Hearing, noise-induced hearing loss, occupational health, personal protective equipment, hearing protection devices 相似文献
8.
9.
10.