全文获取类型
收费全文 | 3677篇 |
免费 | 226篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 129篇 |
妇产科学 | 67篇 |
基础医学 | 564篇 |
口腔科学 | 75篇 |
临床医学 | 256篇 |
内科学 | 897篇 |
皮肤病学 | 92篇 |
神经病学 | 355篇 |
特种医学 | 49篇 |
外科学 | 353篇 |
综合类 | 29篇 |
一般理论 | 2篇 |
预防医学 | 163篇 |
眼科学 | 196篇 |
药学 | 309篇 |
中国医学 | 31篇 |
肿瘤学 | 311篇 |
出版年
2024年 | 3篇 |
2023年 | 43篇 |
2022年 | 67篇 |
2021年 | 105篇 |
2020年 | 36篇 |
2019年 | 81篇 |
2018年 | 96篇 |
2017年 | 71篇 |
2016年 | 100篇 |
2015年 | 97篇 |
2014年 | 108篇 |
2013年 | 145篇 |
2012年 | 221篇 |
2011年 | 288篇 |
2010年 | 151篇 |
2009年 | 134篇 |
2008年 | 253篇 |
2007年 | 286篇 |
2006年 | 245篇 |
2005年 | 282篇 |
2004年 | 247篇 |
2003年 | 228篇 |
2002年 | 226篇 |
2001年 | 26篇 |
2000年 | 25篇 |
1999年 | 38篇 |
1998年 | 35篇 |
1997年 | 31篇 |
1996年 | 32篇 |
1995年 | 21篇 |
1994年 | 24篇 |
1993年 | 13篇 |
1992年 | 16篇 |
1991年 | 15篇 |
1990年 | 12篇 |
1989年 | 14篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1986年 | 12篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 7篇 |
1980年 | 9篇 |
1979年 | 10篇 |
1978年 | 6篇 |
1974年 | 4篇 |
1972年 | 2篇 |
1969年 | 2篇 |
排序方式: 共有3916条查询结果,搜索用时 15 毫秒
1.
Hori Hiroki Ohta Asuka Matsui Honami Yano Kanako Morita-Tominaka Miyuki Linn Zayar Masumoto Daisuke Okumura Yosuke Okamura Satoshi Kurihara Kosuke Hayakawa Akira Rikiishi Takeshi Kobayashi Kyoko 《International journal of clinical oncology / Japan Society of Clinical Oncology》2022,27(1):245-252
International Journal of Clinical Oncology - The practice of cancer diagnosis disclosure to children has been changed with the times. The regulations of clinical trials in the 2000s might change... 相似文献
2.
3.
4.
5.
6.
7.
Kiyohito Yamamoto Koji Onoda Yasuhiro Sawada Kazuya Fujinaga Kyoko Imanaka-Yoshida Toshimichi Yoshida Hideto Shimpo 《Annals of thoracic and cardiovascular surgery》2007,13(5):322-330
BACKGROUND: Pathological changes in vein grafts begin immediately after arterial circulation is applied to the grafts. Chemical mediator stimulation and mechanical strain induce neointimal hyperplasia and medial thickening of the vein grafts, resulting in their failure. We investigated the inhibitory effect of locally applied cilostazol, an inhibitor of cyclic adenosine monophosphate phosphodiesterase III, on neointimal hyperplasia and medial thickening of the grafts. METHODS AND RESULTS: We established a distal anastomotic stricture model of femoral vein-abdominal aorta interposition grafting in rats. In this model, neointimal hyperplasia was observed not only at the distal anastomotic sites, but also in the graft body at postoperative day 14 and was markedly progressed at day 28. A strong expression of tenascin-C was found in the media and neointima of the graft body. In the grafts around which cilostazol was administered locally using Pluronic gel, neointimal hyperplasia was significantly suppressed compared with control grafts treated with the gel alone, with the mean neointimal cross-sectional area reduced by 87.1% for the graft body and by 78.9% for the distal anastomotic sites and mean medial cross-sectional area of the graft body reduced by 54.2% at day 28 versus the control. Cilostazol treatment decreased cell proliferation and the number of tenascin-C-producing cells seen by in situ hybridization, but the expression of tenascin-C protein was not suppressed. CONCLUSION: We concluded that a single perivascular application of cilostazol inhibits neointimal hyperplasia and medial thickening of vein grafts in a rat model. 相似文献
8.
9.
OBJECTIVE: To indicate whether the double peaked N(1) to gaps in continuous white noise is a composite of onset and offset responses to transients or whether it reflects higher processing such as change or mismatch detection and to assess the role of attention in this process. METHODS: Evoked potentials were recorded to two binaural stimulus types: (1) gaps of different durations randomly distributed in continuous white noise; and (2) click pairs at intervals identical to those between gap onsets and offsets in the continuous noise stimulus. Potentials to these stimuli were recorded while subjects read a text and while detecting gaps in noise or click pairs. RESULTS: Potentials were detected to all click pairs and to gaps of 5 ms or longer, corresponding to the subjects' psychoacoustic gap detection threshold. With long gap durations of 200-800 ms, distinct potentials to gap onset and gap offset were observed. The waveforms to all click pairs and to offsets of long gaps were similar and single-peaked, while potentials to gaps of 10 ms and longer, and potentials to onsets of long gaps were double-peaked, consisting of two N(1) negativities, 60 ms apart, irrespective of gap duration. The first (N(1a)), was more frontal in its distribution and similar to that of clicks. The second (N(1b)) peak's distribution was more central/temporal and its source locations and time course of activity were distinct. No effects of attention on any of the varieties and constituents of N(1) were observed. CONCLUSIONS: Comparing potentials to gap onsets, to click pairs and to gap offsets, suggests that potentials to gap onsets involve not only sound onset/offset responses (N(1), N(1a)) but also the subsequent pre-attentive perception of the cessation of an ongoing sound (N(1b)). We propose that N(1b) is distinct from change or mismatch detection and is associated with termination of an ongoing continuous stimulus. We propose to call it the N(egation)-process. SIGNIFICANCE: A constituent of the N(1) complex is shown to be associated with the pre-attentive perception of termination of an ongoing stimulus and to have distinct scalp distribution and intracranial sources. 相似文献
10.
Mikio Mikami Chisei Tei Kyoko Takehara Shinichi Komiyama Atsushi Suzuki Takanori Hirose 《International journal of gynecological pathology》2003,22(2):205-208
A 38-year-old female presented with a lower abdominal mass. During the operation the mass was found to be retroperitoneal and was excised. Gross examination revealed a mucin-containing cystic lesion with a mural nodule. On microscopic examination, the cystic areas were lined by an invasive mucinous adenocarcinoma and the nodule was composed of an anaplastic sarcomatoid tumor that was immunoreactive for cytokeratin. This present case is the 21st example of a retroperitoneal primary mucinous cystadenocarcinoma and the fourth with a mural nodule. Three of four cases with a mural nodule, including our case, had a rapidly fatal outcome. 相似文献