Transcatheter tricuspid valve‐in‐valve implantation for degenerative surgical bio‐prosthesis using SAPIEN 3: A case series

We evaluated early outcomes of transcatheter valve‐in‐valve (ViV) implantation in patients with degenerated bio‐prosthesis in tricuspid position. Total of 5 patients were included in our case series. Baseline native tricuspid valve etiology were highly varied ranging from chest wall trauma, Ebstein anomaly, rheumatic heart disease, infective endocarditis and complex congenital heart disease. These differences also made patient comorbidities highly varied. Procedure details were also varied due to different clinical and technical challenges. All cases underwent successful Tricuspid VIV implantation with satisfactory hemodynamics results. All patients experienced improved clinical symptoms at follow up.     

Serum Inhibin A Level in Preeclampsia and Normotensive Pregnancy

Objective: To compare serum inhibin A levels in pregnancy complicated by preeclampsia and in normotensive pregnancy. Materials and methods: Blood samples were taken from 60 women. Thirty women were diagnosed with preeclampsia, and 30 women had normotensive pregnancies. Both groups were matched for gestational age. Blood samples were collected in plain tubes, centrifuged, and stored at –80°C until analyzed. All serum samples were measured for inhibin A level by enzyme-linked immunosorbent assay (ELISA). Results: Inhibin A levels were greater in the preeclampsia group (1229.7 ± 537.5 pg/mL) than in the normotensive group (839.1 ± 370.0 pg/mL, p = 0.002). Conclusions: Levels of inhibin A in the preeclampsia group were greater than in the normotensive group.     

Inhibin A levels and severity of preeclampsia

Objective  To evaluate the use of third trimester inhibin A levels to assess the severity of preeclampsia. Materials and methods  Blood samples were taken from women diagnosed with mild and severe preeclampsia during the third trimester of pregnancy. Blood samples were collected in plain tubes, centrifuged and stored at −80°C until analyzed. All serum samples were measured for inhibin A levels by enzyme-linked immunosorbent assays. Results  Inhibin A levels were greater in the severe (1,435.9 ± 603.2 pg/mL) than in the mild preeclampsia group (1,021.9 ± 438.8 pg/mL, P = 0.014). Conclusion  Inhibin A levels rise with increasing severity of disease. However, there is considerable overlap of serum inhibin A levels in women with mild and severe preeclampsia. Inhibin A is therefore not a useful adjunct for the classification of preeclampsia. This abstract was presented at the 15th Congress of the Federation of Asia and Oceania Perinatol Societies, Nagoya, Japan.