全文获取类型
收费全文 | 16255篇 |
免费 | 1509篇 |
国内免费 | 43篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 552篇 |
妇产科学 | 475篇 |
基础医学 | 1994篇 |
口腔科学 | 141篇 |
临床医学 | 3896篇 |
内科学 | 2449篇 |
皮肤病学 | 158篇 |
神经病学 | 1572篇 |
特种医学 | 333篇 |
外科学 | 1608篇 |
综合类 | 250篇 |
一般理论 | 21篇 |
预防医学 | 2299篇 |
眼科学 | 136篇 |
药学 | 988篇 |
中国医学 | 8篇 |
肿瘤学 | 843篇 |
出版年
2023年 | 199篇 |
2022年 | 185篇 |
2021年 | 497篇 |
2020年 | 354篇 |
2019年 | 510篇 |
2018年 | 605篇 |
2017年 | 504篇 |
2016年 | 552篇 |
2015年 | 532篇 |
2014年 | 678篇 |
2013年 | 892篇 |
2012年 | 1148篇 |
2011年 | 1250篇 |
2010年 | 629篇 |
2009年 | 541篇 |
2008年 | 852篇 |
2007年 | 886篇 |
2006年 | 807篇 |
2005年 | 738篇 |
2004年 | 675篇 |
2003年 | 591篇 |
2002年 | 561篇 |
2001年 | 236篇 |
2000年 | 179篇 |
1999年 | 268篇 |
1998年 | 257篇 |
1997年 | 224篇 |
1996年 | 300篇 |
1995年 | 233篇 |
1994年 | 218篇 |
1993年 | 169篇 |
1992年 | 175篇 |
1991年 | 175篇 |
1990年 | 150篇 |
1989年 | 120篇 |
1988年 | 108篇 |
1987年 | 64篇 |
1986年 | 76篇 |
1985年 | 66篇 |
1984年 | 69篇 |
1983年 | 52篇 |
1982年 | 47篇 |
1981年 | 31篇 |
1980年 | 28篇 |
1979年 | 37篇 |
1978年 | 26篇 |
1974年 | 33篇 |
1973年 | 35篇 |
1972年 | 24篇 |
1967年 | 25篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Recognizing and managing a deteriorating patient: a randomized controlled trial investigating the effectiveness of clinical simulation in improving clinical performance in undergraduate nursing students
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
5.
6.
Joseph M. Northey Kate L. Pumpa Clare Quinlan Ashley Ikin Kellie Toohey Disa J. Smee Ben Rattray 《Journal of Science and Medicine in Sport》2019,22(5):580-585
Objectives
The current study investigated the effects of two exercise interventions on cognitive function amongst breast cancer survivors.Design
Pilot randomised-controlled trial.Methods
Seventeen female cancer survivors (mean: 62.9 ± 7.8 years) were randomised into three groups: high-intensity interval training (HIIT, n = 6); moderate-intensity continuous training (MOD, n = 5); or wait-list control (CON, n = 6). The HIIT and MOD groups exercised on a cycle ergometer 3 days/week for 12-weeks. Primary outcomes were cognitive function assessments utilising CogState. Secondary outcomes were resting middle cerebral artery blood flow velocity, cerebrovascular reactivity and aerobic fitness (VO2peak). Data were analysed with General Linear Mixed Models and Cohen’s d effect sizes were calculated.Results
All 17 participants who were randomised were available for follow-up analysis and adherence was similar for HIIT and MOD (78.7 ± 13.2% vs 79.4 ± 12.0%; p = 0.93). Although there were no significant differences in the cognitive and cerebrovascular outcomes, HIIT produced moderate to large positive effects in comparison to MOD and CON for outcomes including episodic memory, working memory, executive function, cerebral blood flow and cerebrovascular reactivity. HIIT significantly increased VO2peak by 19.3% (d = 1.28) and MOD had a non-significant 5.6% (d = 0.72) increase, compared to CON which had a 2.6% decrease.Conclusions
This study provides preliminary evidence that HIIT may be an effective exercise intervention to improve cognitive performance, cerebrovascular function and aerobic fitness in breast cancer survivors. Considering the sample size is small, these results should be confirmed through larger clinical trials. 相似文献7.
Interaction effects between the 5‐hydroxy tryptamine transporter‐linked polymorphic region (5‐HTTLPR) genotype and family conflict on adolescent alcohol use and misuse
下载免费PDF全文
![点击此处可从《Addiction (Abingdon, England)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
8.
9.
Fiene Marie Kuijper Uma V. Mahajan Seul Ku Daniel A.N. Barbosa Sheila M. Alessi Sherman C. Stein Kyle M. Kampman Brandon S. Bentzley Casey H. Halpern 《Neuromodulation》2022,25(2):253-262
ObjectivesCocaine is the second most frequently used illicit drug worldwide (after cannabis), and cocaine use disorder (CUD)-related deaths increased globally by 80% from 1990 to 2013. There is yet to be a regulatory-approved treatment. Emerging preclinical evidence indicates that deep brain stimulation (DBS) of the nucleus accumbens may be a therapeutic option. Prior to expanding the costly investigation of DBS for treatment of CUD, it is important to ensure societal cost-effectiveness.AimsWe conducted a threshold and cost-effectiveness analysis to determine the success rate at which DBS would be equivalent to contingency management (CM), recently identified as the most efficacious therapy for treatments of CUDs.Materials and MethodsQuality of life, efficacy, and safety parameters for CM were obtained from previous literature. Costs were calculated from a societal perspective. Our model predicted the utility benefit based on quality-adjusted life-years (QALYs) and incremental-cost-effectiveness ratio resulting from two treatments on a one-, two-, and five-year timeline.ResultsOn a one-year timeline, DBS would need to impart a success rate (ie, cocaine free) of 70% for it to yield the same utility benefit (0.492 QALYs per year) as CM. At no success rate would DBS be more cost-effective (incremental-cost-effectiveness ratio <$50,000) than CM during the first year. Nevertheless, as DBS costs are front loaded, DBS would need to achieve success rates of 74% and 51% for its cost-effectiveness to exceed that of CM over a two- and five-year period, respectively.ConclusionsWe find DBS would not be cost-effective in the short term (one year) but may be cost-effective in longer timelines. Since DBS holds promise to potentially be a cost-effective treatment for CUDs, future randomized controlled trials should be performed to assess its efficacy. 相似文献
10.