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Visnuvinayagam S. Murthy L. N. Parvathy U. Jeyakumari A. Adiga Thriveni G. Sivaraman G. K. 《Proceedings of the National Academy of Sciences, India. Section B.》2019,89(2):559-564
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Occurrence of faecal indicator bacteria (FIB) is being reported regularly by various researchers. But there... 相似文献
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Background
In the majority of the cases of portal vein thrombosis in India, the etiology cannot be determined. A high level of factor VIII (FVIII) is a risk factor for venous thromboembolism.Methods
In this study from South India, FVIII was estimated in 32 patients with idiopathic portal vein thrombosis (PVT), 12 healthy controls and 12 disease controls with chronic liver disease.Results
Eighty-four percent of the patients with portal vein thrombosis (27/32) vs 17% of healthy controls (2/12) had high factor VIII levels (P <.0001). FVIII levels were significantly different between the subset of PVT patients with normal liver function compared with healthy controls (P <.001) and also between the subset of PVT patients with abnormal liver function compared with disease controls (P <.05).Conclusions
A high factor VIII level seems to contribute to the development of portal vein thrombosis in India. 相似文献4.
Factor V Leiden is not commonly associated with idiopathic portal vein thrombosis in southern India. 总被引:2,自引:0,他引:2
BACKGROUND: Factor V Leiden has been reported in 2%-30% of patients with portal vein thrombosis. This wide variation makes it difficult to assess the importance of factor V Leiden as a predisposing factor. METHODS: Factor V Leiden was determined by restriction fragment length polymorphism in 112 patients with portal vein thrombosis, 104 with deep vein thrombosis and 98 control subjects. RESULTS: Only 3/112 (3%) patients with portal vein thrombosis had factor V Leiden, compared to 1/98 (1%) controls and 16/104 (15%) with deep vein thrombosis; of these, 3, 1 and 15, respectively, were heterozygous for this mutation. CONCLUSION: Factor V Leiden contributes little, if at all, to the development of portal vein thrombosis in southern India. 相似文献
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Prothrombin G20210A gene variant is not associated with idiopathic portal vein thrombosis in an area endemic for portal vein thrombosis 总被引:1,自引:0,他引:1
Prothrombin G20210A gene variant has been found in 0–23% of patients with portal vein thrombosis (PVT). This wide variation
makes it difficult to assess the importance of prothrombin G20210A gene variant as a predisposing factor for PVT. In this
study from South India, none of the patients with idiopathic PVT (0/38) or any of the controls (0/46) had prothrombin G20210A
gene variant. Prothrombin G20210A gene variant does not contribute to the development of PVT in India. 相似文献
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Narasimha Murthy L. Phadke Girija G. Jeyakumari A. Parvathy U. Visnuvinayagam S. 《Proceedings of the National Academy of Sciences, India. Section B.》2018,88(4):1647-1653
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Careful handling of fish and shellfish onboard at the vessel is of prime importance in order to maintain the... 相似文献
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