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Wenzel Jan-Per Petersen Elina Nikorowitsch Julius Müller Jessica Kölbel Tilo Reichenspurner Hermann Blankenberg Stefan Girdauskas Evaldas 《The international journal of cardiovascular imaging》2021,37(12):3439-3449
The International Journal of Cardiovascular Imaging - To evaluate the prevalence of aortic regurgitation (AR) and associations between the individual aortic root components and AR severity in the... 相似文献
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Struppek Julia Walther Carolin Bunte Kübra Zyriax Birgit-Christiane Wenzel Jan-Per Senftinger Juliana Nikorowitsch Julius Heydecke Guido Seedorf Udo Beikler Thomas Borof Katrin Mayer Carola Aarabi Ghazal 《Clinical oral investigations》2022,26(3):2421-2427
Clinical Oral Investigations - Positive and negative influences on oral health are attributed to coffee consumption. The aim of the current study is to evaluate the association between coffee... 相似文献
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Wenzel Jan-Per Petersen Elina Nikorowitsch Julius Senftinger Juliana Sinning Christoph Theissen Matthias Petersen Johannes Reichenspurner Hermann Girdauskas Evaldas 《The international journal of cardiovascular imaging》2021,37(12):3513-3524
The International Journal of Cardiovascular Imaging - Here we generate up-to-date reference values of transthoracic echocardiographic aortic root dimensions matched by sex, age, and body surface... 相似文献
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Ilaria My MD Marc D. Lemoine MD Mahi Butt Celine Mencke Fabian W. Loeck MD Julius Obergassel MD Laura Rottner MD Jan-Per Wenzel MD Ruben Schleberger MD Julia Moser MD Fabian Moser Paulus Kirchhof MD Bruno Reissmann MD Feifan Ouyang MD Andreas Rillig MD Andreas Metzner MD 《Journal of cardiovascular electrophysiology》2023,34(9):1802-1807
Introduction
Pulsed-field ablation (PFA) and the multielectrode radiofrequency balloon (RFB) are two novel ablation technologies to perform pulmonary vein isolation (PVI). It is currently unknown whether these technologies differ in lesion formation and lesion extent. We compared the acute lesion extent after PVI induced by PFA and RFB by measuring low-voltage area in high-density maps and the release of biomolecules reflecting cardiac injury.Methods
PVI was performed with a pentaspline catheter (FARAPULSE) applying PFA or with the compliant multielectrode RFB (HELIOSTAR). Before and after PVI high-density mapping with CARTO 3 was performed. In addition, blood samples were taken before transseptal puncture and after post-PVI remapping and serum concentrations of high-sensitive Troponin I were quantified by immunoassay.Results
Sixty patients undergoing PVI by PFA (n = 28, age 69 ± 12 year, 60% males, 39.3% persistent atrial fibrillation [AF]) or RFB (n = 32, age 65 ± 13 year, 53% males, 21.9% persistent AF) were evaluated. Acute PVI was achieved in all patients in both groups. Mean number of PFA pulses was 34.2 ± 4.5 and mean number RFB applications was 8.5 ± 3 per patient. Total posterior ablation area was significantly larger in PFA (20.7 ± 7.7 cm²) than in RFB (7.1 ± 2.09 cm²; p < .001). Accordingly, posterior ablation area for each PV resulted in larger lesions after PFA versus RFB (LSPV 5.2 ± 2.7 vs. 1.9 ± 0.8 cm², LIPV 5.5 ± 2.3 vs. 1.9 ± 0.8 cm², RSPV 4.7 ± 1.9 vs. 1.6 ± 0.5 cm², RIPV 5.3 ± 2.1 vs. 1.6 ± 0.7 cm,² respectively; p < .001). In a subset of 38 patients, increase of hsTropI was higher after PFA (625 ± 138 pg/mL, n = 28) versus RFB (148 ± 36 pg/mL, n = 10; p = .049) supporting the evidence of larger lesion extent by PFA.Conclusion
PFA delivers larger acute lesion areas and higher troponin release upon successful PVI than multielectrode RFB-based PVI in this single-center series. 相似文献
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