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1.
Jadidi Nilofar Alesaeidi Samira Arab Fatemeh Pakzad Bahram Siasi Elham Esmaeilzadeh Emran 《Clinical rheumatology》2022,41(11):3487-3494
Clinical Rheumatology - MiRSNPs may interfere with mRNA stability through effects on microRNAs (miRNAs)-mRNA interactions via direct changes in miRNA binding site or effect on the secondary... 相似文献
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Mazinani Mahdi Tajik-Mansoury Mohammad Ali Sabour Mahsa Jadidi Majid 《The international journal of cardiovascular imaging》2021,37(6):2079-2084
The International Journal of Cardiovascular Imaging - In myocardial gated SPECT imaging each cardiac cycle is divided into 8 or 16 temporal frames and the cause of the difference between 8 and 16... 相似文献
4.
Most – if not all – proteins are bound to interact with other proteins to exert their function, and thus the identification
of the interaction partners of a protein is vital in proteomics. The yeast two-hybrid system is a popular and effective tool
for studyingprotein–protein interactions. Although the advantages of the system are manifold, it also has certain drawbacks
and limitations. The two-hybrid system has been shown to be extremely useful for placing a protein of unknown function within
a functional context, thereby providing information about a putative role of the uncharacterised protein. This concept has
also been successfully applied in molecular gerontology.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
5.
Gholamreza Azizi Farhad Jadidi‐Niaragh Abbas Mirshafiey 《International journal of rheumatic diseases》2013,16(3):243-253
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the sequestration of various leukocyte subpopulations within both the developing pannus and synovial space. The chronic nature of this disease results in inflammation of multiple joints, with subsequent destruction of the joint cartilage and erosion of bone. Identification of T helper (Th)17 cells led to breaking the dichotomy of the Th1/Th2 axis in immunopathogenesis of autoimmune diseases such as RA, and its experimental model, collagen‐induced arthritis (CIA). Th17 cells produce cytokines, including interleukin (IL)‐17, IL‐6, IL‐21, IL‐22 and tumor necrosis factor (TNF)‐α, with pro‐inflammatory effects, which appear to have a role in immunopathogenesis of RA. Regarding the wide ranging production of pro‐inflammatory cytokines and chemokines by Th17 cells, it is expected that Th17 cell could be a potent pathogenic factor in disease immunopathophysiology. Thus the identification of effector mechanisms used by Th17 cells in induction of disease lesions may open new prospects for designing a new therapeutic strategy for treatment of RA. 相似文献
6.
Amir S. Jadidi Hubert Cochet Ashok J. Shah Steven J. Kim Edward Duncan Shinsuke Miyazaki Maxime Sermesant Heiko Lehrmann Matthieu Lederlin Nick Linton Andrei Forclaz Isabelle Nault Lena Rivard Matthew Wright Xingpeng Liu Daniel Scherr Stephen B. Wilton Laurent Roten Patrizio Pascale Nicolas Derval Frédéric Sacher Sebastien Knecht Cornelius Keyl Mélèze Hocini Michel Montaudon Francois Laurent Michel Haïssaguerre Pierre Jaïs 《Journal of the American College of Cardiology》2013
7.
Objective
Examine the effect of stimulus duration, intensity and level of muscle contraction on the inhibitory responses evoked by electrical stimuli in human jaw-closing muscles applied to the right mental nerve.Design
The inhibitory jaw-reflexes, short-latency (ES1) and long-latency (ES2), were recorded in the surface electromyogram (EMG) of masseter and temporalis muscles in 16 healthy subjects. Three stimulus durations (1 ms single square-wave pulse, 10 and 450 ms square-wave pulse train), two stimulus intensities adjusted to perceived intensity of 3 (non-painful) and 7 (distinct painful) on a 0–10 verbal rating scale were applied to the right mental nerve while the subject was biting at 25% and 50% of the maximal voluntary contraction (MVC).Results
The magnitude of suppression in the ES2 evoked by 1 and 10 ms stimuli was dependent on stimulus intensity (P < 0.002 and P < 0.001, respectively) but not contraction level. However, ES1 could not be observed in most of the recordings. There were significant decreases evoked by the 450 ms stimuli in RMS–EMG values in the 400–500 ms compared with the pre-stimulus interval (P < 0.001) which was dependent on contraction level (P < 0.01) but not on stimulus intensity (P = 0.486).Conclusions
The present results suggest that the ES2 reflex response is associated with the duration of the electrical stimuli, the intensity level but not the contraction level. In contrast, the inhibitory effects of ultra-long stimuli (450 ms) are not specifically related to the intensity level suggesting that this is a non-nociceptive response. 相似文献8.
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Comparison among Ocular Response Analyzer, Corvis ST and Goldmann applanation tonometry in healthy children
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Ramin Salouti Ali agha Alishiri Reza Gharebaghi Mostafa Naderi Khosrow Jadidi Ahmad Shojaei-Baghini Mohammadreza Talebnej Zahra Nasiri Seyedmorteza Hosseini Fatemeh Heidary 《国际眼科》2018,11(8):1330-1336
AIM: To explore the relationship between different parameters of Ocular Response Analyzer (ORA) and Corvis ST (CST) in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 instruments against intraocular pressure (IOP), measured by the Goldmann applanation tonometer (GAT-IOP), age and gender, and find possible correlation between ORA and CST with GAT.
METHODS: This cross-sectional study included 90 healthy children. A general interview and complete eye examination were performed. Following successful GAT-IOP measurement, ORA and CST were conducted. The CST parameters were A 1/2 length (A1L, A2L), A 1/2 velocity (A1V, A2V), highest concavity deformation amplitude (HCDA), radius of curvature (RoC), peak distance (PD), central corneal thickness (CCT) and IOP. The ORA parameters were corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated IOP (IOP-G) and corneal compensated IOP (IOP-CC). Extracted data was analyzed using the Statistical Package for Social Science software.
RESULTS: Totally 39 males with age of 9.08±1.60 (6-12)y and 51 females with age of 8.96±1.55 (6-13)y were included. Many CST parameters were significantly correlated with CH, CRF, IOP-G and IOP-CC. Some CST parameters had a significant correlation with GAT-IOP, including IOP-CST in both eyes and HCDA, A2L, PD, and RoC in the left eye, but none with age, except A2L in the right eye. The CRF measurement showed a significant correlation with GAT-IOP in both eyes and CH in the right eye, yet, none with age. Among all CST and ORA parameters, CCT-CST in both eyes and A1L in right eye had a significant correlation with gender, although this was a negligible negative correlation. Comparison of mean IOP values by different devices showed a significantly highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Also, IOP-G versus IOP-CST significantly had the lowest IOP overestimation among others. Overall, either low positive correlation or negligible correlation was found between IOP measurements by 3 instruments.
CONCLUSION: The study finds the highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Overall, either low positive correlation or negligible correlation is found between IOP measurements by the 3 instruments. 相似文献