全文获取类型
收费全文 | 383篇 |
免费 | 23篇 |
国内免费 | 26篇 |
专业分类
儿科学 | 23篇 |
妇产科学 | 4篇 |
基础医学 | 53篇 |
口腔科学 | 3篇 |
临床医学 | 45篇 |
内科学 | 89篇 |
皮肤病学 | 2篇 |
神经病学 | 9篇 |
特种医学 | 71篇 |
外科学 | 26篇 |
综合类 | 17篇 |
预防医学 | 21篇 |
眼科学 | 1篇 |
药学 | 45篇 |
中国医学 | 2篇 |
肿瘤学 | 21篇 |
出版年
2022年 | 5篇 |
2020年 | 3篇 |
2018年 | 6篇 |
2017年 | 3篇 |
2016年 | 2篇 |
2015年 | 7篇 |
2014年 | 2篇 |
2013年 | 6篇 |
2012年 | 6篇 |
2011年 | 4篇 |
2010年 | 6篇 |
2009年 | 11篇 |
2008年 | 6篇 |
2007年 | 17篇 |
2006年 | 18篇 |
2005年 | 15篇 |
2004年 | 2篇 |
2003年 | 2篇 |
2002年 | 10篇 |
2001年 | 6篇 |
2000年 | 8篇 |
1999年 | 10篇 |
1998年 | 18篇 |
1997年 | 13篇 |
1996年 | 11篇 |
1995年 | 9篇 |
1994年 | 13篇 |
1993年 | 13篇 |
1992年 | 9篇 |
1991年 | 6篇 |
1990年 | 13篇 |
1989年 | 13篇 |
1988年 | 20篇 |
1987年 | 19篇 |
1986年 | 13篇 |
1985年 | 22篇 |
1984年 | 13篇 |
1983年 | 10篇 |
1982年 | 18篇 |
1981年 | 5篇 |
1980年 | 9篇 |
1979年 | 7篇 |
1978年 | 6篇 |
1977年 | 3篇 |
1976年 | 6篇 |
1975年 | 1篇 |
1973年 | 1篇 |
1968年 | 1篇 |
1967年 | 1篇 |
1962年 | 1篇 |
排序方式: 共有432条查询结果,搜索用时 15 毫秒
1.
2.
报道新化合物A-失碳-17β-羟基-17α-乙炔基-Δ3(5),9(10)-雌甾二烯-2-酮2的合成。文中探讨了用炔钾粗品对A-失碳-Δ3(5),9(10)-雌甾二烯-2,17-二酮1和A-失碳-6β,19-环氧-Δ3-雄甾-2,17-二酮3的选择性炔化,分别得标题化合物2(44%)及A-失碳-17β-羟基-17α-乙炔基-6β,19-环氧-Δ3雄甾-2-酮4(65%),4经还原性破开环氧、去羟甲基和去醋酰氧基合成了标题化合物2。四步总收率为34%。 相似文献
3.
Two modified helical basket extractors are described that have increased the success rate of removing ureteral calculi using fluoroscopy from 63% to 92%. Initially a rather stiff and expandable basket with a 20-cm filiform tip is used with coaxial catheters and sheath (stage 1). If this procedure is unsuccessful, a basket with two long cable ends is passed from the nephrostomy out through the urethra (stage 2). When used with coaxial bladder catheters, this technique allows dilatation of the vesicoureteric junction and retrograde catheterization and injection of fluids or gas to dislodge the stone prior to extraction. In a series of 38 patients, stones were removed in all but three (a success rate of 92%). In five cases small stones (less than 5 mm) were not retrieved but subsequent studies were normal. Ureteral stones were found in the abdominal ureter in 28 cases, in the pelvic ureter in seven cases, and in multiple sites in three cases. Stones were larger than 1 cm in 27.7% of cases. Postextraction mucosal edema with reduced ureteral patency was common but usually cleared in 2-3 days. Occasional complications were related to the nephrostomy. 相似文献
4.
D J Flournoy M C Robinson 《Methods and findings in experimental and clinical pharmacology》1990,12(8):541-544
Three hundred and forty-nine methicillin resistant Staphylococcus aureus (MRSA) isolates from veterans were tested (by disc agar diffusion) for their in vitro activity against 18 antimicrobial agents. At least 90% of the isolates were susceptible to bacitracin, nitrofurantoin, hydrogen peroxide, novobiocin, netilmicin and vancomycin. We feel that the aminoglycoside, netilmicin, might provide an alternative agent (to intravenously administered vancomycin) for treating multiply-antimicrobial resistant MRSA. In addition, hydrogen peroxide exhibited very good activity against the test isolates and may have some use as a topical agent for reduction of MRSA on skin and some mucous membranes. This study suggests that further evaluation of netilmicin and hydrogen peroxide (topical only) might be useful. 相似文献
5.
6.
Retrorenal colon: implications for percutaneous diskectomy 总被引:1,自引:0,他引:1
It has been recommended that computed tomography (CT) with the patient prone be performed in every patient undergoing percutaneous diskectomy; this would enable detection of a retrorenal location of the colon, which could interfere with the percutaneous procedure. In this evaluation of 346 prone CT studies, only one patient (0.29%) was found to have retrorenal or retropsoas bowel that would have been perforated at diskectomy. Because of this extremely low prevalence, the performance of prone CT in every patient undergoing percutaneous lumbar diskectomy is not believed to be necessary. 相似文献
7.
8.
L B Hinshaw T E Emerson F B Taylor A C Chang M Duerr G T Peer D J Flournoy G L White S D Kosanke C K Murray 《The Journal of trauma》1992,33(4):568-573
A successful experimental treatment for gram-positive sepsis to our knowledge has not been achieved. The objectives of this study were to develop a nonhuman primate model of lethal gram-positive sepsis employing the micro-organism Staphylococcus aureus and to determine the efficacy of treatment using monoclonal antibody (MAb) to tumor necrosis factor alpha (TNF). The antibody was administered intravenously, 15 mg/kg, 30 minutes after the beginning of a 2-hour infusion of S. aureus, 4 x 10(10) colony forming units/kilogram. The baboons infused with S. aureus demonstrated the release of the cytokines TNF and interleukin-6 (IL-6), but endotoxin was not observed in the plasma at any time. Treatment with antibody to TNF abolished the rise in serum TNF levels and reduced the increased levels of IL-6. Treatment with MAb to TNF prevented multiple organ failure and achieved permanent (> 7 day) survival of all baboons. 相似文献
9.
10.
D J Flournoy S M Qadri D R Downard L Woolridge 《Journal of the National Medical Association》1987,79(10):1073-1075
Antinuclear antibody and rheumatoid arthritis factor test results were compared between two nearby hospitals of approximately the same size but with different patient populations. There were dramatic differences in percentage of positive results, titers, and patterns (for antinuclear antibody tests) between the two institutions. 相似文献