全文获取类型
收费全文 | 9814篇 |
免费 | 1329篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 31篇 |
儿科学 | 221篇 |
妇产科学 | 820篇 |
基础医学 | 1034篇 |
口腔科学 | 43篇 |
临床医学 | 3396篇 |
内科学 | 1562篇 |
皮肤病学 | 134篇 |
神经病学 | 812篇 |
特种医学 | 153篇 |
外科学 | 653篇 |
综合类 | 30篇 |
一般理论 | 3篇 |
预防医学 | 825篇 |
眼科学 | 87篇 |
药学 | 585篇 |
中国医学 | 11篇 |
肿瘤学 | 768篇 |
出版年
2024年 | 18篇 |
2023年 | 231篇 |
2022年 | 124篇 |
2021年 | 246篇 |
2020年 | 221篇 |
2019年 | 207篇 |
2018年 | 364篇 |
2017年 | 332篇 |
2016年 | 433篇 |
2015年 | 406篇 |
2014年 | 511篇 |
2013年 | 649篇 |
2012年 | 595篇 |
2011年 | 643篇 |
2010年 | 465篇 |
2009年 | 537篇 |
2008年 | 563篇 |
2007年 | 554篇 |
2006年 | 489篇 |
2005年 | 418篇 |
2004年 | 454篇 |
2003年 | 384篇 |
2002年 | 341篇 |
2001年 | 123篇 |
2000年 | 65篇 |
1999年 | 157篇 |
1998年 | 175篇 |
1997年 | 155篇 |
1996年 | 156篇 |
1995年 | 134篇 |
1994年 | 96篇 |
1993年 | 76篇 |
1992年 | 73篇 |
1991年 | 72篇 |
1990年 | 81篇 |
1989年 | 58篇 |
1988年 | 43篇 |
1987年 | 38篇 |
1986年 | 26篇 |
1985年 | 58篇 |
1984年 | 27篇 |
1983年 | 36篇 |
1982年 | 35篇 |
1981年 | 31篇 |
1980年 | 21篇 |
1979年 | 25篇 |
1978年 | 26篇 |
1977年 | 14篇 |
1976年 | 19篇 |
1969年 | 11篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Quality of life in stroke survivor–caregiver dyads: a new conceptual framework and longitudinal study protocol 下载免费PDF全文
2.
3.
Erika Cecon Anna Ivanova Marine Luka Florence Gbahou Anne Friederich Jean‐Luc Guillaume Patrick Keller Klaus Knoch Raise Ahmad Philippe Delagrange Michele Solimena Ralf Jockers 《Journal of pineal research》2019,66(2)
Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non‐24‐hour sleep‐wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT1 and MT2, belonging to the G protein‐coupled receptor (GPCR) superfamily. Similar to most other GPCRs, reliable antibodies recognizing melatonin receptors proved to be difficult to obtain. Here, we describe the development of the first monoclonal antibodies (mABs) for mouse MT1 and MT2. Purified antibodies were extensively characterized for specific reactivity with mouse, rat, and human MT1 and MT2 by Western blot, immunoprecipitation, immunofluorescence, and proximity ligation assay. Several mABs were specific for either mouse MT1 or MT2. None of the mABs cross‐reacted with rat MTRs, and some were able to react with human MTRs. The specificity of the selected mABs was validated by immunofluorescence microscopy in three established locations (retina, suprachiasmatic nuclei, pituitary gland) for MTR expression in mice using MTR‐KO mice as control. MT2 expression was not detected in mouse insulinoma MIN6 cells or pancreatic beta‐cells. Collectively, we report the first monoclonal antibodies recognizing recombinant and native mouse melatonin receptors that will be valuable tools for future studies. 相似文献
4.
5.
Gwyneth R. Milbrath MSN MPH RN Pamela B. DeGuzman PhD MBA RN 《Public health nursing (Boston, Mass.)》2015,32(4):349-358
Researchers interested in measuring neighborhood‐level effects should understand how “neighborhood” is defined within nursing sciences and other sciences, and the inherent strengths and weaknesses of current research methodologies. This concept analysis provides clarity around the concept of neighborhood within the context of health, analyzes the current state of development of the neighborhood concept, and proposes areas for future nursing research. Using the Rodger's Method of analysis, the concept of neighborhood within nursing and public health research is described based on existing literature. The concept's attributes, related concepts, antecedents, and consequences are given from the literature. Comparisons of the use of neighborhood are made between nursing, public health, sociology, and other sciences. The evolution of the concept of neighborhood throughout history is described, and important implications for future research are discussed. 相似文献
6.
7.
8.
9.
Abdelhadi Lahoum Nasserdine Sabaou Christian Bijani Noureddine Bouras Frédéric Pont Selma P. Snini Florence Mathieu 《Saudi Pharmaceutical Journal》2019,27(1):56-65
The actinobacterium strain ABH26 closely related to Saccharothrix xinjiangensis, isolated from an Algerian Saharan soil sample, exhibited highly antagonist activity against Gram-positive bacteria, yeasts and filamentous fungi. Its ability to produce antimicrobial compounds was investigated using several solid culture media. The highest antimicrobial activity was obtained on Bennett medium. The antibiotics secreted by strain ABH26 on Bennett medium were extracted by methanol and purified by reverse-phase HPLC using a C18 column. The chemical structures of the compounds were determined after spectroscopic (1H NMR, 13C NMR, 1H-1H COSY and 1H-13C HMBC spectra), and spectrometric (mass spectrum) analyses. Two new cyanogriside antibiotics named cyanogriside I (1) and cyanogriside J (2), were characterized along with three known caerulomycins, caerulomycin A (3), caerulomycin F (4) and caerulomycinonitrile (5). This is the first report of cyanogrisides and caerulomycins production by a member of the Saccharothrix genus. The minimum inhibitory concentrations (MIC) of these antibiotics were determined against pathogenic microorganisms. 相似文献
10.