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Chin Chin Ooi BAppSc MMedUS Foong Koon Cheah MBChB MRCP FRCR Siew Kune Wong MBBS FRCR FAMS 《Journal of clinical ultrasound : JCU》2015,43(7):438-442
We report a case of rare Castleman's disease of the kidney that mimicked a renal neoplasm with emphasis on the imaging and histologic findings. A 47‐year‐old man presented with dyspeptic symptoms. Ultrasound revealed a vascular, heterogeneous mass in the left kidney. Multiphasic CT scan confirmed an enhancing lesion with enlarged left para‐aortic lymph nodes suspicious for nodal metastases. The provisional diagnosis was renal cell carcinoma. Percutaneous biopsy yielded a diagnosis of Castleman's disease of the hyaline‐vascular type. Despite advancement in imaging modalities, differentiation of hyaline‐vascular variant of Castleman's disease from hypervascular renal neoplasm remains difficult and the final diagnosis requires histopathological confirmation. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43 :438–442, 2015 相似文献
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Dhayan Timbadia Ashlynn Ler Faizus Sazzad MBBS MS FCPS FACS Christos Alexiou MD PhD FRCS FRCS CCST Theo Kofidis MD PD FRCS FAHA FAMS 《Journal of cardiac surgery》2020,35(10):2785-2793
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Wei‐Yi Ong BDS PhD Kang Sim MBBS MMed FAMS Akhlaq A. Farooqui PhD 《Asia-Pacific psychiatry》2010,2(4):180-190
Schizophrenia is a complex neuropsychiatric disorder with a prevalence of nearly 1% of the world population. Accumulating evidence suggests that increase in production of reactive oxygen species (ROS) along with decrease in antioxidants and antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase) may be closely associated with the pathogenesis of schizophrenia. Genes associated with glutamate transmission, dopamine transmission, synaptic plasticity, mitochondrial function, oxidative stress, lipid metabolism, and neuroinflammation have been closely linked to schizophrenia. Proteins encoded by many of the above genes affect the level of ROS, and lipid mediators that regulate signaling in the brain through cross‐talk among glutamate, dopamine, and eicosanoid receptors. Under physiological conditions, this refines the communication between neurons, glial cells and vascular cells, but in schizophrenia, the cross‐talk might initiate and promote oxidative stress‐mediated abnormal neuronal signaling responsible for symptoms of the disease. 相似文献
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Yue Yu MBBS MRCS Rehena Sultana MSc Mahalakshmi S. Rangabashyam MBBS MRCSEd DipNB Niraj Mohan MBBS Jacqueline S. G. Hwang MBBS FRCPA FAMS Yoke-Lim Soong MBBS FRCR FFRRCSI Ngian-Chye Tan MBBS MMed FRCSEd FAMS Gopalakrishna N. Iyer MBBS PhD FRCSEd FAMS Hiang-Khoon Tan MBBS FRCSEd FAMS PhD 《The Laryngoscope》2020,130(8):1947-1953