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1.
Kann Holmén RN Doctoral Student Kjerstin Ericsson RN PhD Researcher Lars Andersson DMSc Associate Professor Bengt Winblad MD Professor 《Journal of advanced nursing》1992,17(1):43-51
The purpose was to investigate experienced loneliness among the elderly. The material included 1725 people, aged 75 and over. The study describes relationships between loneliness, social network, cognitive function and health. Thirty-five per cent experienced loneliness, and a higher percentage was found among women. A gradual increase in loneliness was found up to the age of 90, after which a levelling was found. Elderly persons living together with a partner experienced less loneliness. There were no significant differences between those with and without children. Ten per cent reported not having any friends and, of these, one out of two experienced loneliness. A high frequency of experienced loneliness was found among elderly people with reduced cognitive function. Subjectively experienced bad health and loneliness were strongly related to each other, i.e. a person who experienced loneliness did usually not feel completely healthy. 相似文献
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Silvia Helena de Bortoli Cassiani RN MN Doctoral student Assistant Professor Maria Lúcia Zanetti RN MN Doctoral student Assistant Professor Nilza Teresa Rotter Pelá RN DNS Head of the 《Journal of advanced nursing》1992,17(5):576-581
Studies have shown that students and the general population have little knowledge about nursing schools and the nursing profession. This study investigates the extent to which a sample of the population of Brazil is aware of the existence of nursing schools, and how they have obtained this information. Data were collected by telephone interviews. The sample consisted of 326 subjects whose telephone numbers were taken from the telephone book. Analysis showed that 73% of the subjects were aware of the existence of two nursing schools in the city; however, 65.03% did not know the names of these schools. Direct communication with friends and family, as well as indirect communication by television and advertising, were the sources of information mentioned by those questioned. 相似文献
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肇自晋唐、盛于明清的“新安医学”在中医学发展史中具有重要地位。作者对新安临床医家中具有代表性的医学家族 :徽州歙县定潭“张一帖”的源流进行了详细考证。认为“张一帖”之名起于明嘉靖年间 ,传承至今 ,计 45 0余年、15代的历史。张氏历代以急性热病、内科疑难杂病为其精擅 ,传有“末药”等名方 ,并对张氏各代的临床特色予以简要考辨、探讨。认为区域性医学流派、代表性医学家族链曾是中医学发展过程中的重要建构形式之一。 相似文献
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Neeraj Sriram MD Candidate Gary R. Hunter PhD Gordon Fisher PhD David W. Brock PhD 《Journal of clinical hypertension (Greenwich, Conn.)》2014,16(3):172-176
Recent studies have reported a strong association between blood pressure (BP) and resting energy expenditure (REE). However, it is not known whether this relationship persists over time. Therefore, the authors examined the temporal relationship between REE and systolic BP. In addition, the impact of sympathetic tone and anthropometric variables on this relationship was examined. All testing was performed on healthy, overweight African American and European American women aged 25 to 45 years over 4.5 years in the University of Alabama at Birmingham General Clinical Research Center. Repeated‐measures mixed‐models revealed REE as a significant determinant of systolic BP (β=0.0155, P<.0001), independent of catecholamines, leg fat, visceral fat, fat‐free mass, fat mass, height, relative skeletal muscle index, and resting heart rate. Observations that REE is predictive of systolic BP across 4.5 years support previous findings that REE may potentially mediate resting BP, independent of anthropometric variables and a marker for sympathetic tone. 相似文献
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PB Shetty H Tang BO Tayo AC Morrison CL Hanis DC Rao JH Young ER Fox E Boerwinkle RS Cooper NJ Risch X Zhu;the Candidate Gene Association Resource 《Journal of hypertension》2012,30(10):1970-1976
OBJECTIVE:: Genetic variants in 296 genes in regions identified through admixture mapping of hypertension, BMI, and lipids were assessed for association with hypertension, blood pressure (BP), BMI, and high-density lipoprotein cholesterol (HDL-C). METHODS:: This study identified coding SNPs identified from HapMap2 data that were located in genes on chromosomes 5, 6, 8, and 21, wherein ancestry association evidence for hypertension, BMI, or HDL-C was identified in previous admixture mapping studies. Genotyping was performed in 1733 unrelated African-Americans from the National Heart, Lung and Blood Institute's Family Blood Pressure Project, and gene-based association analyses were conducted for hypertension, SBP, DBP, BMI, and HDL-C. A gene score based on the number of minor alleles of each SNP in a gene was created and used for gene-based regression analyses, adjusting for age, age, sex, local marker ancestry, and BMI, as applicable. An individual's African ancestry estimated from 2507 ancestry-informative markers was also adjusted for to eliminate any confounding due to population stratification. RESULTS:: CXADR (rs437470) on chromosome 21 was associated with SBP and DBP with or without adjusting for local ancestry (P?0.0006). F2RL1 (rs631465) on chromosome 5 was associated with BMI (P?=?0.0005). Local ancestry in these regions was associated with the respective traits as well. CONCLUSION:: This study suggests that CXADR and F2RL1 likely play important roles in BP and obesity variation, respectively; and these findings are consistent with those of other studies, so replication and functional analyses are necessary. 相似文献
7.
Leila H. Shayegan BA MD Candidate Maria C. Garzon MD Kimberly D. Morel MD Rachel Borlack MD Patricia M. Vuguin MD Kara G. Margolis MD Yesim Y. Demirdag MD Elaine M. Pereira MD Christine T. Lauren MD MHA 《Pediatric dermatology》2020,37(4):695-697
We report a case of a newly recognized primary immunodeficiency due to biallelic mutations in CARMIL2 manifesting as an actinic prurigo-like photodermatitis, allergic diathesis and recurrent infections in a child. We present this case to highlight a rare phenotype seen in this T-cell immunodeficiency and provide an overview of other dermatologic manifestations among published reports of this condition. 相似文献
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