全文获取类型
收费全文 | 3959篇 |
免费 | 276篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 156篇 |
妇产科学 | 63篇 |
基础医学 | 458篇 |
口腔科学 | 32篇 |
临床医学 | 648篇 |
内科学 | 552篇 |
皮肤病学 | 52篇 |
神经病学 | 765篇 |
特种医学 | 65篇 |
外科学 | 291篇 |
综合类 | 57篇 |
一般理论 | 4篇 |
预防医学 | 618篇 |
眼科学 | 35篇 |
药学 | 208篇 |
中国医学 | 6篇 |
肿瘤学 | 202篇 |
出版年
2023年 | 13篇 |
2022年 | 23篇 |
2021年 | 63篇 |
2020年 | 40篇 |
2019年 | 65篇 |
2018年 | 75篇 |
2017年 | 53篇 |
2016年 | 64篇 |
2015年 | 82篇 |
2014年 | 89篇 |
2013年 | 148篇 |
2012年 | 255篇 |
2011年 | 285篇 |
2010年 | 147篇 |
2009年 | 133篇 |
2008年 | 263篇 |
2007年 | 274篇 |
2006年 | 253篇 |
2005年 | 273篇 |
2004年 | 225篇 |
2003年 | 228篇 |
2002年 | 232篇 |
2001年 | 70篇 |
2000年 | 60篇 |
1999年 | 49篇 |
1998年 | 46篇 |
1997年 | 52篇 |
1996年 | 32篇 |
1995年 | 24篇 |
1994年 | 34篇 |
1993年 | 19篇 |
1992年 | 41篇 |
1991年 | 33篇 |
1990年 | 42篇 |
1989年 | 41篇 |
1988年 | 41篇 |
1987年 | 18篇 |
1986年 | 24篇 |
1985年 | 33篇 |
1984年 | 28篇 |
1983年 | 22篇 |
1982年 | 35篇 |
1981年 | 28篇 |
1980年 | 15篇 |
1979年 | 24篇 |
1977年 | 14篇 |
1976年 | 12篇 |
1975年 | 14篇 |
1974年 | 13篇 |
1973年 | 14篇 |
排序方式: 共有4240条查询结果,搜索用时 15 毫秒
1.
2.
3.
Jill Downie Rose Chapman Angelica Orb Dianne Juliff 《The Australian journal of advanced nursing》2002,19(3):15-24
The traditional role of the high school based community community health nurse has changed considerably over recent decades. This article describes a qualitative study, in which nine community health nurses from eight different high schools completed a diary of the interventions and events during the course of two working days in order to identify the dimensions of their role. A short demographic questionnaire was also completed by the nurses and included two open-ended questions concerning their main professional issues and concerns. The researchers sought verification of the interpretation of the data through a focus group interview with the high school nurses. Data analysis indicated that the role of the high school community health nurses (CHN) consisted of seven categories. These were provider of clinical care, counsellor/ mediator, advocacy and support, liaison/referral, health promotion/education and resource agent, and professional management and research role. The findings highlight the complex and demanding aspects of the role of the high school nurse and articulate the importance of describing the contribution of such practitioners in to the promotion of health among adolescents. 相似文献
4.
Scott E Strome Elizabeth Martin Dallas Flies Dianne Khurana Diva Salomao Koji Tamada Andrei I Chapoval Jan L Kasperbauer Kerry D Olsen Lieping Chen 《Otolaryngology--head and neck surgery》2002,126(2):180-187
OBJECTIVES: CD62L was evaluated as a determinant of human pre-effector T cells. STUDY DESIGN AND SETTING: Phenotype and cytokine secretion profiles of CD62L cells were determined based on activation status. RESULTS: CD62L(Low) T cells demonstrated significantly higher secretion of interleukin (IL)-10 and interferon (IFN)-gamma than did CD62L(High) T cells. After activation, the majority of cells expressed high levels of the CD62L surface marker. Postactivation levels of IL-10 production remained elevated or unchanged. In a murine B16 melanoma model, freshly isolated CD62L(Low) tumor draining lymph nodes (TDLN) T cells showed increased secretion of IL-2 and IL-4 but not of IL-10 or IFN-gamma. The surface expression of CD62L and cytokine secretion patterns were maintained after activation with concomitant increases in IL-10. CONCLUSION: Our results provide evidence that CD62L(Low) T cells in TDLNs of progressively growing squamous cell carcinoma of the head and neck differ phenotypically and functionally from those of mouse origin. SIGNIFICANCE: Characterization of this human CD62L(Low) T cell population provides initial insight regarding novel surface markers in TDLN T cells that might correlate with antitumor reactivity. 相似文献
5.
Edbert B Hsu Tamara L Thomas Eric B Bass Dianne Whyne Gabor D Kelen Gary B Green 《BMC medical education》2006,6(1):19-9
Background
Although training and education have long been accepted as integral to disaster preparedness, many currently taught practices are neither evidence-based nor standardized. The need for effective evidence-based disaster training of healthcare staff at all levels, including the development of standards and guidelines for training in the multi-disciplinary health response to major events, has been designated by the disaster response community as a high priority. We describe the application of systematic evidence-based consensus building methods to derive educational competencies and objectives in criteria-based preparedness and response relevant to all hospital healthcare workers. 相似文献6.
Two-tiered DNA-based diagnosis of transthyretin amyloidosis reveals two novel point mutations 总被引:4,自引:0,他引:4
We analyzed 11 consecutive unrelated cases of polyneuropathy due to transthyretin amyloidosis. Direct sequencing of the promoter region, exons, and splice junctions revealed that each patient was heterozygous for a mutation: six patients had valine 30 substituted by methionine (V30----M; Portuguese-Japanese type), one had threonine 60 substituted by alanine (T60----A; Appalachian type), and two had serine 77 substituted by tyrosine (S77----Y; Illinois type). In addition, two patients had previously undescribed mutation: phenylalanine 33 substituted by leucine (F33----L) and phenylalanine 64 substituted by leucine (F64----L). From present information, the probands of these novel mutations do not exhibit any pathology that clearly distinguishes them from individuals with the other mutations. The mutations extend the range of mutations associated with amyloidotic polyneuropathy. In our 11 patients, the different mutations did not seem to correlate with distinct clinical phenotypes. We developed PASA assays (PCR amplification of specific alleles) for each of the five mutations. PASA can be used by any diagnostic laboratory that can perform PCR to rapidly detect any of the known mutations. The minority of samples with an undescribed mutation can be sent to a specialty laboratory for delineation of the mutation by direct genomic sequencing. The presently described combination of methods may have widespread utility in the diagnosis of genetic disease. 相似文献
7.
Chronic obstructive pulmonary disease is one of the most significant chronic illnesses of adults. Comprehensive care of the affected patient requires the medical-surgical nurse to have knowledge of the disease process, collaborative management, and nursing care based on research and current practice guidelines. 相似文献
8.
We examine the relationships between glycemic carbohydrate and its effects on short-term satiety and food intake. Both high- and low-glycemic carbohydrates have an impact on satiety, but their effects have different time courses. High-glycemic carbohydrates are associated with a reduction in appetite and food intake in the short term (e.g., one hour), whereas the satiating effects of lower-glycemic carbohydrates appear to be delayed (e.g., 2 to 3 hours). There is no consistent evidence that an increase in blood glucose, either acute or sustained, is the primary determinant of their effects on food intake and satiety. Many other preabsorptive and postabsorptive signals for satiety exist and may be the determining factors. Further studies are needed to delineate the role of glycemic carbohydrates and their mechanisms of action in determining satiety. 相似文献
9.
10.
The Great Safety Performance model uses leading indicators to drive injury prevention and provides a process to improve a company's safety outcomes by maximizing the conditions for safety within the workplace. The model asserts that leaders and workers need to jointly create conditions whereby everyone will know what to do, be able to do it, be equipped to do it, want to do it, and experience interactions that support safe performance in their job duties. These factors are referred to as the conditions for great performance. The Great Safety Performance model can serve as a vehicle to quantify, document, and demonstrate the efforts a company invests to create a safe workplace with safe work practices. By using the Great Safety Performance model, organizations can design and implement a variety of high leverage improvement initiatives specific to their business situations. 相似文献