全文获取类型
收费全文 | 784篇 |
免费 | 64篇 |
国内免费 | 15篇 |
专业分类
儿科学 | 21篇 |
妇产科学 | 4篇 |
基础医学 | 128篇 |
口腔科学 | 8篇 |
临床医学 | 65篇 |
内科学 | 186篇 |
皮肤病学 | 10篇 |
神经病学 | 24篇 |
特种医学 | 142篇 |
外科学 | 66篇 |
综合类 | 40篇 |
预防医学 | 22篇 |
眼科学 | 12篇 |
药学 | 112篇 |
中国医学 | 1篇 |
肿瘤学 | 22篇 |
出版年
2021年 | 4篇 |
2019年 | 6篇 |
2018年 | 7篇 |
2017年 | 11篇 |
2016年 | 12篇 |
2015年 | 8篇 |
2014年 | 12篇 |
2013年 | 21篇 |
2012年 | 13篇 |
2011年 | 12篇 |
2010年 | 18篇 |
2009年 | 26篇 |
2008年 | 17篇 |
2007年 | 29篇 |
2006年 | 28篇 |
2005年 | 24篇 |
2004年 | 23篇 |
2003年 | 30篇 |
2002年 | 22篇 |
2001年 | 19篇 |
2000年 | 23篇 |
1999年 | 29篇 |
1998年 | 34篇 |
1997年 | 43篇 |
1996年 | 37篇 |
1995年 | 30篇 |
1994年 | 34篇 |
1993年 | 20篇 |
1992年 | 19篇 |
1991年 | 19篇 |
1990年 | 11篇 |
1989年 | 28篇 |
1988年 | 17篇 |
1987年 | 26篇 |
1986年 | 15篇 |
1985年 | 15篇 |
1984年 | 6篇 |
1983年 | 17篇 |
1982年 | 11篇 |
1981年 | 12篇 |
1980年 | 9篇 |
1979年 | 5篇 |
1978年 | 6篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1974年 | 4篇 |
1973年 | 7篇 |
1972年 | 9篇 |
1969年 | 3篇 |
排序方式: 共有863条查询结果,搜索用时 15 毫秒
1.
2.
杨兴旺 《眼外伤职业眼病杂志》1994,16(3):202-204
采用综合治疗,抗炎,散瞳,局部治疗与全身应用免疫抑制疗法,治疗319例352眼外伤获得了满意的疗效,眼球挫伤104例,眼球穿孔伤93例,化学烧伤71例,眼炸伤46例。眼热烧伤5例,治疗包括及时清创胶粘或缝合,清除前房出血合理用皮质类固醇和免疫抑制剂等。眼球挫伤治愈率97.12%,穿透伤93.18%,热烧伤66.67%。319例眼外伤治愈率94.67%好转5.33%,并对各种治疗方法进行了讨论。 相似文献
3.
4.
Retrorenal colon: implications for percutaneous diskectomy 总被引:1,自引:0,他引:1
It has been recommended that computed tomography (CT) with the patient prone be performed in every patient undergoing percutaneous diskectomy; this would enable detection of a retrorenal location of the colon, which could interfere with the percutaneous procedure. In this evaluation of 346 prone CT studies, only one patient (0.29%) was found to have retrorenal or retropsoas bowel that would have been perforated at diskectomy. Because of this extremely low prevalence, the performance of prone CT in every patient undergoing percutaneous lumbar diskectomy is not believed to be necessary. 相似文献
5.
6.
Frances Chung Doris Tong Paula C. Miceli Joseph Reiz Zoltan Harsanyi Andrew C. Darke Lance W. Payne 《Journal canadien d'anesthésie》2004,51(3):216-221
PURPOSE: Following ambulatory surgery, long-acting analgesics may provide advantages over short-acting analgesics. This study compared controlled-release codeine (CC) and acetaminophen plus codeine (A/C; 300 mg/30 mg) for pain control in the 48-hr period following laparoscopic cholecystectomy. METHODS: Eligible patients were randomized to CC or A/C in a double-blind, double-dummy parallel group study. Unrelieved pain in hospital was treated with fentanyl i.v. bolus. Pain [100 mm visual analogue scale (VAS)] was assessed before the first dose of medication; at 0.5, one, two, three, and four hours post-dose; at discharge; and three times a day for 48 hr. Adverse events were recorded and measures of patient satisfaction were assessed at the end of the study. RESULTS: Eighty-four patients were enrolled in the study; 42 patients in each group. There were no statistically significant differences between CC and A/C treatment. Mean VAS baseline pain was similar in both groups (P = 0.49) and there was no significant difference in the time to onset of analgesia (P = 0.17). At 0.5 hr, the mean VAS pain score was significantly reduced from baseline in both groups (P = 0.0001). The VAS pain scores at discharge were reduced 59% and 56% from baseline, respectively (P = 0.61). There was no difference between treatments in the incidence of adverse events and patients reported similar levels of satisfaction. CONCLUSIONS: Controlled-release codeine provides an equivalent onset of analgesia, reduction in postoperative pain, and level of patient satisfaction, to acetaminophen plus codeine, over 48 hr following cholecystectomy, with the advantage of less frequent dosing. 相似文献
7.
PL Macken FRACO FRACS CJ Pavlin FRCS R Tuli MD GE Trope PhD FRCS 《Clinical & experimental ophthalmology》1995,23(3):217-220
Background: Spherophakia is an uncommon diagnosis. This is the first case report of spherophakia evaluated by ultrasound biomicroscopy.
Methods: Ultrasound biomicroscopy is a new diagnostic technique developed by one of the authors and provides images with microscopic resolution of the anterior segment. A patient with spherophakia was evaluated by ultrasound biomicroscopy (Zeiss-Humphrey, 50MHz) before and after YAG laser iridotomy.
Results: Ultrasound biomicroscopic assessment revealed a shallow anterior chamber, a very steep anterior lens curvature, iridolenticular contact, elongated zonules, and an increased distance between the lens equator and the ciliary processes. Angle closure glaucoma was due to a pupil block mechanism. The pupil block was relieved by YAG laser iridotomy.
Conclusions: Ultrasound biomicroscopy is a useful technique to confirm the diagnosis of spherophakia. The pupil block in spherophakia is relieved by YAG laser iridotomy. 相似文献
Methods: Ultrasound biomicroscopy is a new diagnostic technique developed by one of the authors and provides images with microscopic resolution of the anterior segment. A patient with spherophakia was evaluated by ultrasound biomicroscopy (Zeiss-Humphrey, 50MHz) before and after YAG laser iridotomy.
Results: Ultrasound biomicroscopic assessment revealed a shallow anterior chamber, a very steep anterior lens curvature, iridolenticular contact, elongated zonules, and an increased distance between the lens equator and the ciliary processes. Angle closure glaucoma was due to a pupil block mechanism. The pupil block was relieved by YAG laser iridotomy.
Conclusions: Ultrasound biomicroscopy is a useful technique to confirm the diagnosis of spherophakia. The pupil block in spherophakia is relieved by YAG laser iridotomy. 相似文献
8.
T J Tucker W C Lumma L S Payne J M Wai S J de Solms E A Giuliani P L Darke J C Heimbach J A Zugay W A Schleif 《Journal of medicinal chemistry》1992,35(14):2525-2533
A series of HIV-1 protease inhibitors containing a novel hydroxyethyl secondary amine transition state isostere has been synthesized. The compounds exhibit a strong preference for the (R) stereochemistry at the transition state hydroxyl group. Molecular modeling studies with the prototype compound 11 have provided important insights into the structural requirements for good inhibitor-active site binding interaction. N-Terminal extension of 11 into the P2-P3 region led to the discovery of 19, the most potent enzyme inhibitor in the series (IC50 = 5.4 nM). 19 was shown to have potent antiviral activity in cultured MT-4 human T-lymphoid cells. Comparison of analogs of 19 with analogs of 1 (Ro31-8959) demonstrates that considerably different structure-activity relationships exist between these two subclasses of hydroxyethylamine HIV-protease inhibitors. 相似文献
9.
1,6—二磷酸果糖对手术后应激病人应用全肠外营养支持效果的影响 总被引:3,自引:1,他引:2
本文在胃癌行全胃或胃大部切除术引起的中等程度应激病人,随机分组对比观察了全肠外营养或TPN加用1,6-二磷酸果糖的效果。结果显示,与单纯TPN相比,TPN加用FDP后血清皮质醇和胰高血糖素等应激激素水平有所下降,尿中3-甲基组氨酸排出减少,累积氮平衡增加。 相似文献
10.