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Fine arterial branches on the superior surface of corpus callosum were investigated on 22 human brains under stereomicroscope. These branches were directed toward: 1. the upper surface of corpus callosum (3-6 branches, mean 8), 2. the depths of the sulcus corporis callosi (4-13 branches, mean 7), and 3. the cingulate gyrus (1-10 branches, mean 5). All the vessels composing the pericallosal pial plexus have a uniformed caliber of 0.9-0.6 mm at their origins, and 0.7-0.3 mm after branching. In 9 cases a longitudinal vessel within the stria longitudinalis medialis, connected with the pial plexus was found. Important details of morphology of this plexus and their significance are discussed. 相似文献
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Miroslav Marek Michael Roman Danica Dosko
ilov Svatopluk Pokorný 《Macromolecular chemistry and physics.》1986,187(10):2337-2344
The polymerization of 3-chloro-2-methyl-1-propene was investigated at temperatures between 0 and ?80°C, using AlCl3 and AlBr3 as initiators. The molecular weights of the resulting oily products depend on the polymerization temperature and varied in the range of the number-average molecular weight M?n = 400–620. The course of polymerization was studied and the characteristic groupings in the oligomeris were identified by means of 1H NMR and 13C NMR spectroscopy. Based on the results the mechanism of partial reactions was discussed to explain the new type of propagation in the cationic polymerization. 相似文献
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Population‐based study shows that resuscitating apparently stillborn extremely preterm babies is associated with poor outcomes
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Dr. Predrag Sikirić PhD Sven Seiwerth PhD Željko Grabarević PhD Rudolf Ručman PhD Marijan Petek PhD Vjekoslav Jagić PhD Branko Turković PhD Ivo Rotkvić PhD Stjepan Miše PhD Ivan Zoričić MD Miroslav Gjurašin MD Paško Konjevoda MD Jadranka Šeparović PhD Danica Ljubanović MD Branka Artuković MD Mirna Bratulić MD Marina Tišljar MD Ljubica Jurina MD Gojko Buljat PhD Pavao Miklić PhD Anton Marović PhD 《Digestive diseases and sciences》1996,41(8):1604-1614
Very recently, the integrity of capsaicin somatosensory neurons and their protection were suggested to be related to the activity in nociception of a newly discovered 15-amino acid peptide, BPC 157, shown to have strong beneficial effect on intestinal and liver lesions. Therefore, from this viewpoint, we have studied the gastroprotective effect of the pentadecapeptide BPC 157, on gastric lesions produced in rats by 96% ethanol, restraint stress, and indomethacin. The possible involvement of sensory neurons in the salutary actions of BPC 157 (10µg/kg, 10 ng/kg intraperitoneally) was studied with capsaicin, which has differential effects on sensory neurons: a high dose in adult (125 mg/kg subcutaneously, 3 months old) or administration (50 mg/kg subcutaneously) to neonatal animals (age of the 7 days) destroys sensory fibers, whereas a low dose (500µg/kg intraperitoneally) activates neurotransmitter release and protective effects on the mucosa. In the absence of capsaicin, BPC 157 protected gastric mucosa against ethanol, restraint, and indomethacin application. In the presence of neurotoxic doses of capsaicin, the negative influence of capsaicin on restraint, ethanol, or indomethacin lesions consistently affected salutary activity of BPC 157. However, BPC 157 protection was still evident in the capsaicin-treated rats (either treated as adults or as newborns) in all of these assays. Interestingly, after neonatal capsaicin treatment, a complete abolition of BPC gastroprotection was noted if BPC 157 was applied as a single nanogram-regimen, but the mucosal protection was fully reversed when the same dose was used daily. In line with the excitatory dose of capsaicin the beneficial effectiveness of BPC 157 appears to be increased as well. Taken together, these data provide evidence for complex synergistic interaction between the beneficial effectiveness of BPC 157 and peptidergic sensory afferent neuron activity. 相似文献