全文获取类型
收费全文 | 596篇 |
免费 | 45篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 41篇 |
妇产科学 | 4篇 |
基础医学 | 59篇 |
口腔科学 | 20篇 |
临床医学 | 43篇 |
内科学 | 103篇 |
皮肤病学 | 13篇 |
神经病学 | 31篇 |
特种医学 | 97篇 |
外科学 | 69篇 |
综合类 | 62篇 |
一般理论 | 2篇 |
预防医学 | 16篇 |
眼科学 | 12篇 |
药学 | 25篇 |
肿瘤学 | 39篇 |
出版年
2023年 | 3篇 |
2022年 | 7篇 |
2021年 | 9篇 |
2020年 | 10篇 |
2019年 | 10篇 |
2018年 | 11篇 |
2017年 | 10篇 |
2016年 | 15篇 |
2015年 | 23篇 |
2014年 | 9篇 |
2013年 | 17篇 |
2012年 | 17篇 |
2011年 | 28篇 |
2010年 | 24篇 |
2009年 | 21篇 |
2008年 | 21篇 |
2007年 | 24篇 |
2006年 | 25篇 |
2005年 | 28篇 |
2004年 | 13篇 |
2003年 | 16篇 |
2002年 | 19篇 |
2001年 | 12篇 |
2000年 | 9篇 |
1999年 | 13篇 |
1998年 | 32篇 |
1997年 | 26篇 |
1996年 | 20篇 |
1995年 | 17篇 |
1994年 | 13篇 |
1993年 | 11篇 |
1992年 | 5篇 |
1991年 | 3篇 |
1990年 | 4篇 |
1989年 | 15篇 |
1988年 | 14篇 |
1987年 | 15篇 |
1986年 | 12篇 |
1985年 | 7篇 |
1984年 | 5篇 |
1983年 | 8篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 6篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1976年 | 3篇 |
1975年 | 8篇 |
1974年 | 3篇 |
1969年 | 3篇 |
排序方式: 共有645条查询结果,搜索用时 15 毫秒
1.
Trevor J. Royce Kathleen T. Davenport James M. Dahle 《Practical radiation oncology》2019,9(4):231-238
PurposePhysician burnout is reported in more than one out of every 2 practicing clinicians and is just as prevalent in training physicians. Burnout severity is also associated with increasing levels of financial debt. Medical professionals are notable for their high and increasing levels of debt; despite this, financial literacy is poor among physicians, and financial education is largely absent from medical education. Radiation oncologists (ROs) are no different in this regard, with 33% of residents reporting high levels of burnout symptoms, 33% carrying >$200,000 of educational debt, and 75% reporting being unprepared to handle future financial decisions. To fill this gap, we reviewed the basic tenets of personal financial health for the early career RO.Methods and materialsThe core concept of financial independence (FI) is introduced, and we review 4 basic tenets of personal financial health for the young medical professional: debt, behavior, investment, and asset protection strategies.ResultsFI is achieved by saving until the desired quality of life can be maintained, independent of employment income. Debt strategy involves minimizing debt accrual, understanding student loans, and having a debt management plan. Behavioral strategy involves setting financial goals, calculating worth and a savings rate, budgeting, and frugal living. The basics of investing include asset allocation, diversification, rebalancing, and minimizing expenses. Finally, asset protection includes insuring against catastrophic events with disability, life, health, liability, and property insurance.ConclusionsHealthy financial practices can lead to FI and may facilitate professional and personal freedoms with the goal of mitigating burnout-associated stressors. The tenets of strong financial health for ROs in the early stages of their career include sound debt, behavioral, investment, and asset protection strategies. Furthermore, initial and continuing financial education is an overlooked but important curriculum component. ROs with their financial houses in order can devote more resources to learning and practicing good medicine while living healthy, rewarding lives. 相似文献
2.
3.
The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease (AHD), using CT and MR imaging. We retrospectively reviewed CT and MR images of three patients with various adjacent organ invasions surgically and histologically proven to be AHD. Local invasion to right kidney and adrenal, right hemidiaphragm and lung were detected in one patient, right adrenal in another patient and gall bladder, duodenum, gastric wall and pancreas invasion in the other. AHD may rarely extend to the gall bladder, stomach, duodenum, pancreas, right adrenal and kidney, diaphragm, pleura and lung. The extension of the disease outside the liver is usually encountered in patients with large, peripherally located masses in the advanced stage of the disease. 相似文献
4.
5.
C McKenzie BAppSc P Megaw BAppSc I Morgan PhD MK Boelen PhD 《Clinical & experimental ophthalmology》1997,25(4):79-81
Deprivation of form vision by the fitting of translucent occluders suppressed the diurnal cycling of enkephalinergic amacrine cells (the ENSLI amacrine cells), in the chicken. Daily periods of normal vision or enforcing temporal contrast using strobe lighting appeared to restore normal functioning of the ENSLI cells. These results suggest that the ENSLI cells are involved in retinal circuits that assess the quality of the visual image and control eye growth. 相似文献
6.
7.
8.
9.
10.
Dahle MK Øverland G Myhre AE Stuestøl JF Hartung T Krohn CD Mathiesen Ø Wang JE Aasen AO 《Infection and immunity》2004,72(10):5704-5711
Sepsis caused by gram-positive bacteria lacking lipopolysaccharide (LPS) has become a major and increasing cause of mortality in intensive-care units. We have recently demonstrated that the gram-positive-specific bacterial cell wall component lipoteichoic acid (LTA) stimulates the release of the proinflammatory cytokines in Kupffer cells in culture. In the present study, we have started to assess the signal transduction events by which LTA induces the production of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), and the anti-inflammatory cytokine IL-10 in rat Kupffer cells. LTA was found to trigger phosphorylation of mitogen-activated protein kinases (MAPK) (p38 MAPK and ERK 1/2) and protein kinase B (PKB). Compared to LPS, LTA was more potent in inducing PKB phosphorylation after 40 min, although we found that the cytokine responses were similar. For both bacterial molecules, blocking phosphatidylinositol 3-kinase (PI3-K; Ly294002) or Janus kinase 2 (JAK-2; AG490) particularly affected the induction of IL-6 and IL-10 release, whereas TNF-alpha levels were strongly reduced by inhibition of Src family tyrosine kinases (PP2). All three cytokines were reduced by inhibition of p38 MAPK (SB202190) or the broad-range tyrosine kinase inhibitor genistein, whereas IL-6 release was particularly blocked by inhibition of ERK 1/2 (PD98059). Divergences in the regulatory pathways controlling TNF-alpha, IL-10, and IL-6 production in Kupffer cells following LPS or LTA stimulation may create a basis for understanding how the balance between pro- and anti-inflammatory cytokines is regulated in the liver following infections by gram-positive or gram-negative bacteria. 相似文献