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1.
It is often difficult for medical professionals to understand the behaviour of people with diabetic foot syndrome. We describe the different psychological factors that play a role in the maintenance of intermittent implementation of medical recommendations. In particular we look at the consequences of neuropathy and of the recommendation to offload pressure, as well as the contradictions between the realities of the patient and the medical professionals involved in their care. We show that the solutions that patients develop are based on normal psychological processes and we encourage professionals to consider these aspects in their relationship to people with DFS and when developing individualised preventative measures. 相似文献
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YP Zverev J Chisi 《Malawi medical journal : the journal of Medical Association of Malawi》2004,16(1):14-16
Handedness is the most important behavioural asymmetry due to its intimate association with the specialisation of the brain for language. It exists in 3 forms, namely right, left and mixed. Left-handers constitute the biggest minority group in the world and in many aspects they are in a disadvantaged position compared to right-handers. Numerous studies demonstrated association between left-handedness and different health problems ranging from learning disorders to breast cancer and decreased longevity. This paper reviews the relevant literature on the genesis of handedness and connection between handedness and health. Deviations from the “normal” pattern of braininess observed in some left-handers might contribute to developmental, cognitive and some mental disorders. However increased incidence of some of pathological conditions among sinistrals could hardly be explained by the “abnormal” pattern of braininess or by the action of a gene or genes responsible for handedness determination. Review of literature suggests that many of health problems of left-handers develop due to environmental, developmental and other mechanisms related to genesis of handedness. 相似文献
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TS RAGHU RAMAN DALJIT SINGH YP JALPOTA PK MENON 《Medical Journal Armed Forces India》1996,52(1):19-22
Of the 253 neonates admitted to a neonate intensive care unit during the period Jan 91 to Sep 93, 43 neonates died. Autopsy was done in 23 of these (53%). The mean duration of stay of the neonates in the intensive care unit prior to death was 5.6 days (range 2 hours to 10 days). Antemortem diagnoses included asphyxia neonatorum (4), meconium aspiration syndrome (2), septicemia (5), prematurity (3), birth trauma (2), congenital anomalies (2), hypoxic ischemic encephalopathy (1), and non-specific diagnosis (4). There were 6 major autopsy findings that, if known prior to death, would have altered clinical management and might have resulted in cure or prolonged survival. There were 8 additional major findings that, if known prior to death, would not have altered management There were 14 minor findings related to major diagnoses but unrelated to the primary cause of death.KEY WORDS: Autopsy, Cause of death, Perinatal mortality 相似文献
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Yara Barbosa Franco Clever Aparecido Valentin Marcelo Kobelnik Jefferson Lins da Silva Clovis Augusto Ribeiro Marta Pereira da Luz 《Materials》2022,15(12)
Nonwoven geotextiles are geosynthetic products that are highly susceptible to ultraviolet degradation because light can reach a large area of the material due to its fiber arrangement. Even with additives, which delay the degradation process, material decomposition still occurs, and therefore the product’s long-term durability can be affected. In this paper, the mechanical and thermal behavior of a commercial nonwoven polyester geotextile subjected to accelerated ultraviolet aging tests were evaluated. The deterioration was evaluated by comparing the physical properties (mass per unit area, thickness, and tensile strength) and thermal behavior (thermogravimetry—TG, thermomechanical analysis—TMA, and differential scanning calorimetry—DSC) before and after exposure times of 500 h and 1000 h. The results showed that the ultraviolet aging tests induced some damage in the polyester fibers, leading to the deterioration of their tensile strength. For 1000 h of exposure, in which the reduction was larger, scanning electron microscopy (SEM) found some superficial disruption of the fibers, indicative of damage. TG and DSC could not capture the effects of UV radiation on polymer degradation, unlike TMA. This latter technique was effective in showing the differences between specimens before and after UV exposure. 相似文献
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We have recently found that antibodies to L-selectin, the homing receptor on neutrophils, are as effective as those to beta 2-integrin at blocking formyl peptide-stimulated aggregation. Therefore, we investigated the requirements for expression of L-selectin and beta 2- integrin on adjacent cells during aggregation. Fluorescence flow cytometry allowed characterization of aggregates on the basis of size and color, as well as antibody binding to these two adhesive molecules. Formyl peptide-stimulated aggregate formation was measured for individual populations fluorescently labeled red (LDS-751) or green (CD44-FITC), and interpopulation red-green cell conjugates. Blocking either the beta 2-integrin or L-selectin adhesive epitope with monoclonal antibody on individual cell populations resulted in an approximately 50% reduction in two-color aggregation as compared with that in unblocked samples. Shedding the L-selectin on a cell population by preincubation with complexes of lipopolysaccharide and its plasma membrane binding protein also decreased aggregation to a control population by approximately 50%. We examined the aggregation of neutrophils from patients genetically deficient in beta 2-integrin and clinically leukocyte adhesion deficient (LAD). LAD adhesion to normal neutrophils was dependent on the expression of L-selectin on LAD cells and beta 2-integrin on normal cells. Thus, the minimum requirement for adhesion between two mixed populations of neutrophils was that one population expressed the beta 2-integrin and the other expressed the L- selectin adhesive epitope. 相似文献
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In vitro assay for protein-protein interaction: carboxyl-terminal 40 residues of simian virus 40 structural protein VP3 contain a determinant for interaction with VP1. 总被引:9,自引:0,他引:9 下载免费PDF全文
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目的观察地佐辛用于心房颤动射频消融术中的疗效。方法 2013年4月-7月随机选取心血管内科拟行心房颤动射频消融术患者45例,根据随机双盲原则分为地佐辛组(D组)、吗啡组(M组)。常规术前探视,记录患者生命体征以及术前疼痛评分、舒适度评分。两组患者于手术开始前30 min静脉分别给予地佐辛5 mg或吗啡5 mg镇痛,术中监测血压、心率、血氧饱和度、心电图和疼痛评分、舒适度评分,根据患者疼痛情况分次静脉给予对应组别用药2~3 mg,术毕记录手术时间,术后2、6、24 h随访患者,评估患者疼痛状况以及不良反应。结果两组患者在手术时间、术中疼痛评级指数、术中疼痛视觉模拟评分差异有统计学意义(P<0.05),术中及术后不良反应发生率差异无统计学意义(P>0.05)。结论地佐辛用于心房颤动射频消融术中镇痛效果优于吗啡,但仍然存在术后恶心、呕吐等不良反应,鉴于目前全身麻醉尚未能完全推行的情况下,地佐辛用于心房颤动消融术中镇痛可作为一种较理想的替代方案。 相似文献