全文获取类型
收费全文 | 1631篇 |
免费 | 84篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 48篇 |
妇产科学 | 8篇 |
基础医学 | 165篇 |
口腔科学 | 17篇 |
临床医学 | 192篇 |
内科学 | 423篇 |
皮肤病学 | 3篇 |
神经病学 | 86篇 |
特种医学 | 334篇 |
外科学 | 88篇 |
综合类 | 16篇 |
预防医学 | 54篇 |
眼科学 | 7篇 |
药学 | 142篇 |
中国医学 | 1篇 |
肿瘤学 | 149篇 |
出版年
2022年 | 5篇 |
2021年 | 21篇 |
2020年 | 9篇 |
2019年 | 11篇 |
2018年 | 21篇 |
2017年 | 16篇 |
2016年 | 20篇 |
2015年 | 26篇 |
2014年 | 25篇 |
2013年 | 29篇 |
2012年 | 37篇 |
2011年 | 49篇 |
2010年 | 30篇 |
2009年 | 37篇 |
2008年 | 40篇 |
2007年 | 52篇 |
2006年 | 40篇 |
2005年 | 38篇 |
2004年 | 37篇 |
2003年 | 28篇 |
2002年 | 38篇 |
2001年 | 29篇 |
2000年 | 30篇 |
1999年 | 34篇 |
1998年 | 60篇 |
1997年 | 47篇 |
1996年 | 69篇 |
1995年 | 53篇 |
1994年 | 44篇 |
1993年 | 47篇 |
1992年 | 37篇 |
1991年 | 40篇 |
1990年 | 28篇 |
1989年 | 60篇 |
1988年 | 58篇 |
1987年 | 55篇 |
1986年 | 53篇 |
1985年 | 59篇 |
1984年 | 40篇 |
1983年 | 38篇 |
1982年 | 40篇 |
1981年 | 34篇 |
1980年 | 14篇 |
1979年 | 17篇 |
1978年 | 16篇 |
1977年 | 32篇 |
1976年 | 26篇 |
1975年 | 21篇 |
1974年 | 18篇 |
1973年 | 8篇 |
排序方式: 共有1737条查询结果,搜索用时 31 毫秒
1.
This study explored the inflammatory mechanism of toxicity of hemoglobin solutions (Hb-S). Human monocytes and mouse activated peritoneal macrophages were incubated with seven different solutions. The first four consisted of non-cross-linked bovine Hb. Of these, Hb-SI was incompletely purified of stromal phospholipids, Hb-SII was contaminated with environmental bacterial endotoxins, Hb-SIII was pure hemoglobin, and Hb-SIV was pure Hb with the addition of superoxide dismutase (SOD), catalase (CAT), and mannitol (M). The other three solutions were made of pure bovine Hb cross-linked with different agents: Hb-SV, reacted with glutaraldehyde; Hb-SVI reacted with bis-3,5-dibromosalicyl fumarate (DBSF); and Hb-SVII reacted with a ring-opened dialdehyde derivative of 5'(pyro)-phosphate of adenosine (ATP) (o-ATP). The reaction of monocytes and macrophages was studied in terms of (a) O2-derived radicals, as determined by the measurement of H2O2 and lipid peroxides; (b) complement factor C3a desArg; (c) 6-keto-prostaglandin F1 alpha (stable metabolite of prostacyclin); and (d) TxB2 (stable metabolite of thromboxane) released into the culture supernatants. The most significant reactions were obtained with the solutions contaminated with stromal phospholipids or bacterial endotoxins. Pure Hb was less reactive. Further reduction in proinflammatory activity was achieved by the addition of oxygen radical-scavengers (SOD, CAT, and M), or by the cross-linking of Hb with DBSF or o-ATP. 相似文献
2.
3.
4.
5.
6.
7.
A randomized controlled trial of electromagnetic therapy in the primary care management of venous leg ulceration 总被引:1,自引:1,他引:0
OBJECTIVE: The aim was to establish the potential efficacy, tolerabilityand side-effect profile of electromagnetic therapy as an adjunctto conventional dressings in the treatment of venous leg ulcers. METHOD: A prospective, randomized, double blind controlled clinicaltrial was carried out in a dedicated leg ulcer clinic basedin one urban general practice. Nineteen patients with leg ulcersof confirmed venous aetiology were assessed. The main outcomemeasures were rate and scale of venous leg ulcer healing, changesin patient-reported pain levels, quality of life, degree ofmobility, side effect profile and acceptability to patientsand staff. RESULTS: Sixty-eight per cent of patients attending this dedicated clinicachieved improvements in the size of their ulcer (4, 21%, healedfully) and in reduced pain levels (P < 0.05) during the trial,despite the chronicity of ulcer histories. Patients treatedwith electromagnetic therapy at 800 Hz were found at day 50to have significantly greater healing (P < 0.05) and paincontrol (P < 0.05) than placebo therapy or treatment with600 Hz. All patients reported improved mobility at the end ofthe study. The electromagnetic therapy was well tolerated bypatients, with no differences between groups in reporting adverseevents, and proved acceptable to staff. CONCLUSION: Despite the small numbers in this pilot study, electromagnetictherapy provided significant gains in the healing of venousleg ulcers and reduction in pain. Keywords. Electromagnetic therapy, RCT, leg ulcers, primary care. 相似文献
8.
9.
10.