全文获取类型
收费全文 | 728篇 |
免费 | 79篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 22篇 |
妇产科学 | 12篇 |
基础医学 | 102篇 |
口腔科学 | 7篇 |
临床医学 | 44篇 |
内科学 | 92篇 |
皮肤病学 | 23篇 |
神经病学 | 97篇 |
特种医学 | 89篇 |
外科学 | 29篇 |
综合类 | 24篇 |
一般理论 | 5篇 |
预防医学 | 172篇 |
眼科学 | 4篇 |
药学 | 50篇 |
肿瘤学 | 22篇 |
出版年
2021年 | 9篇 |
2019年 | 7篇 |
2018年 | 10篇 |
2017年 | 9篇 |
2016年 | 10篇 |
2015年 | 18篇 |
2014年 | 23篇 |
2013年 | 26篇 |
2012年 | 18篇 |
2011年 | 34篇 |
2010年 | 23篇 |
2009年 | 14篇 |
2008年 | 30篇 |
2007年 | 40篇 |
2006年 | 25篇 |
2005年 | 24篇 |
2004年 | 17篇 |
2003年 | 17篇 |
2002年 | 22篇 |
2001年 | 13篇 |
2000年 | 14篇 |
1999年 | 15篇 |
1998年 | 25篇 |
1997年 | 22篇 |
1996年 | 23篇 |
1995年 | 17篇 |
1994年 | 13篇 |
1993年 | 19篇 |
1992年 | 13篇 |
1991年 | 13篇 |
1990年 | 19篇 |
1989年 | 17篇 |
1988年 | 18篇 |
1987年 | 14篇 |
1986年 | 21篇 |
1985年 | 19篇 |
1984年 | 16篇 |
1983年 | 14篇 |
1982年 | 5篇 |
1981年 | 11篇 |
1980年 | 7篇 |
1979年 | 10篇 |
1978年 | 6篇 |
1977年 | 4篇 |
1976年 | 8篇 |
1975年 | 6篇 |
1969年 | 7篇 |
1966年 | 4篇 |
1963年 | 4篇 |
1962年 | 4篇 |
排序方式: 共有811条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
7.
Image-directed percutaneous biopsies with a biopsy gun 总被引:3,自引:0,他引:3
Core tissue for histologic study is believed by many pathologists to be more diagnostic than material from needle aspiration. Recently, a biopsy "gun" has been introduced, which simplifies core biopsies. With this device, 182 biopsies of multiple anatomic sites were performed with ultrasonic, computed tomographic, and fluoroscopic guidance and 18-gauge needles. High-quality histopathologic specimens were obtained in 177 of the biopsies, and diagnostic target tissue was obtained in 167. Only three significant complications occurred: one bleeding complication that required transfusion and two cases of pneumothorax that necessitated placement of chest tubes. The biopsy gun eliminated the disjointed movements of conventional "skinny" needle biopsies, and none of the samples demonstrated significant "crush" artifact or obscuring blood, problems that are commonly associated with manual biopsy techniques. Patient discomfort was decreased with this system compared with that of manual biopsies, and the total procedure time was reduced. Because of these distinct advantages, the authors now use the biopsy gun exclusively for all percutaneous biopsies and recommend that other institutions consider the use of this biopsy method. 相似文献
8.
9.
10.
Protriptyline in obstructive sleep apnea: a double-blind trial 总被引:6,自引:0,他引:6
L G Brownell P West P Sweatman J C Acres M H Kryger 《The New England journal of medicine》1982,307(17):1037-1042
We evaluated protriptyline, a nonsedating tricyclic antidepressant, as a treatment for obstructive sleep apnea in a double-blind crossover study of five men. After two weeks of treatment, with no change in body weight, daytime somnolence was markedly reduced and nocturnal oxygenation was improved, although apnea duration and frequency were not significantly decreased. Rapid-eye-movement (REM) stage time as a fraction of the total sleep time was reduced during treatment from 0.231 +/- 0.031 to 0.107 +/- 0.013 (mean +/- S.E.M.) (P less than 0.05). REM apnea time as a fraction of total sleep time was reduced from 0.145 +/- 0.022 to 0.054 +/- 0.006 (P less than 0.05). REM reduction during treatment with protriptyline can account for decreased REM apnea time. Similar decreases in REM stage time and REM apnea duration and similar improvement in oxygenation continued after six months of treatment. In addition, body weight, apnea, and arousal frequency were decreased at this time. Although the obstructive sleep apnea was not resolved, it was reduced. Protriptyline can be effective in patients with sleep apnea when the disorder is not life-threatening. 相似文献