全文获取类型
收费全文 | 4359篇 |
免费 | 271篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 26篇 |
儿科学 | 104篇 |
妇产科学 | 45篇 |
基础医学 | 590篇 |
口腔科学 | 108篇 |
临床医学 | 320篇 |
内科学 | 871篇 |
皮肤病学 | 121篇 |
神经病学 | 390篇 |
特种医学 | 169篇 |
外科学 | 602篇 |
综合类 | 22篇 |
一般理论 | 3篇 |
预防医学 | 185篇 |
眼科学 | 126篇 |
药学 | 552篇 |
中国医学 | 9篇 |
肿瘤学 | 405篇 |
出版年
2023年 | 61篇 |
2022年 | 121篇 |
2021年 | 172篇 |
2020年 | 106篇 |
2019年 | 116篇 |
2018年 | 151篇 |
2017年 | 104篇 |
2016年 | 147篇 |
2015年 | 141篇 |
2014年 | 159篇 |
2013年 | 185篇 |
2012年 | 271篇 |
2011年 | 293篇 |
2010年 | 164篇 |
2009年 | 156篇 |
2008年 | 228篇 |
2007年 | 243篇 |
2006年 | 186篇 |
2005年 | 207篇 |
2004年 | 195篇 |
2003年 | 175篇 |
2002年 | 147篇 |
2001年 | 86篇 |
2000年 | 98篇 |
1999年 | 96篇 |
1998年 | 24篇 |
1997年 | 21篇 |
1996年 | 18篇 |
1995年 | 18篇 |
1994年 | 13篇 |
1993年 | 14篇 |
1992年 | 66篇 |
1991年 | 52篇 |
1990年 | 49篇 |
1989年 | 53篇 |
1988年 | 50篇 |
1987年 | 32篇 |
1986年 | 28篇 |
1985年 | 22篇 |
1984年 | 23篇 |
1983年 | 16篇 |
1982年 | 11篇 |
1981年 | 8篇 |
1980年 | 8篇 |
1979年 | 20篇 |
1978年 | 15篇 |
1976年 | 8篇 |
1974年 | 8篇 |
1971年 | 8篇 |
1969年 | 8篇 |
排序方式: 共有4648条查询结果,搜索用时 31 毫秒
1.
Shimon Kurasawa Takahiro Imaizumi Shoichi Maruyama Keitaro Tanaka Yoko Kubo Mako Nagayoshi Hiroaki Ikezaki Sadao Suzuki Teruhide Koyama Chihaya Koriyama Aya Kadota Sakurako Katsuura-Kamano Kiyonori Kuriki Kenji Wakai Keitaro Matsuo 《International journal of cancer. Journal international du cancer》2023,153(4):732-741
The association between kidney function and cancer incidence is inconsistent among previous reports, and data on the Japanese population are lacking. It is unknown whether kidney function modifies the cancer risk of other factors. We aimed to evaluate the association of estimated glomerular filtration rate (eGFR) with cancer incidence and mortality in 55 242 participants (median age, 57 years; 55% women) from the Japan Multi-Institutional Collaborative Cohort Study. We also investigated differences in cancer risk factors between individuals with and without kidney dysfunction. During a median 9.3-year follow-up period, 4278 (7.7%) subjects developed cancer. Moderately low and high eGFRs were associated with higher cancer incidence; compared with eGFR of 60-74 ml/min/1.73 m2, the adjusted hazard ratios (HRs) (95% confidence intervals [CIs]) for eGFRs of ≥90, 75-89, 45-59, 30-44 and 10-29 ml/min/1.73 m2 were 1.18 (1.07-1.29), 1.09 (1.01-1.17), 0.93 (0.83-1.04), 1.36 (1.00-1.84) and 1.12 (0.55-2.26), respectively. High eGFR was associated with higher cancer mortality, while low eGFR was not; the adjusted subdistribution HRs (95% CIs) for eGFRs of ≥90 and 75-89 ml/min/1.73 m2 were 1.58 (1.29-1.94) and 1.27 (1.08-1.50), respectively. Subgroup analyses of participants with eGFRs ≥60 and <60 ml/min/1.73 m2 revealed elevated cancer risks of smoking and family history of cancer in those with eGFR <60 ml/min/1.73 m2, with significant interactions. Our findings suggest that the relationship between eGFR and cancer incidence was U-shaped. Only high eGFR was associated with cancer mortality. Kidney dysfunction enhanced cancer risk from smoking. 相似文献
2.
Hiroto Kinoshita Hitomi Nishioka Aya Ikeda Kyoko Ikoma Yoichi Sameshima Hidehisa Ohi Mizuki Tatsuno Junka Kouyama Chiaki Kawamoto Tomohiro Mitsui Yuko Tamura Yu Hashimoto Masashi Nishio Tsuyoshi Ogashiwa Yusuke Saigusa Shin Maeda Hideaki Kimura Reiko Kunisaki Kazuhiko Koike 《Journal of gastroenterology and hepatology》2019,34(11):1929-1939
3.
4.
Kentaro Matsubara Yasuhiro Fujimoto Hideya Kamei Kohei Ogawa Mureo Kasahara Mikiko Ueda Hiroto Egawa Yasutsugu Takada Masaki Kitajama Koichi Tanaka 《Liver transplantation》2005,11(11):1444-1447
Living-donor liver transplantation (LDLT) has become an established technique to treat children with end-stage liver disease. Biliary atresia (BA), one of the most common indications for liver transplantation in children, can be associated with situs inversus (SI). In the past, the presence of SI has been considered to be an absolute contraindication for liver transplantation because of the technical difficulties. Recently, some reports of successful diseased-donor liver transplantation in patients with BA complicated by SI have been published; however, few reports of that with LDLT exist. The technical difficulties involved with LDLT for such cases have not been described. Herein, we present 4 successful cases of LDLT for BA with SI. Complex anomalies associated with SI, such as a hepatic artery arising from the supraceliac aorta, a preduodenal portal vein, and absence of the retrohepatic inferior vena cava, increase the technical difficulties involved with the operation. Additional caution is required in LDLT because a living-donor graft has short vessels and the availability of vascular grafts from the donor is limited. In conclusion, LDLT for BA complicated by SI can be managed successfully with technical modifications and scrupulous attention. This series represents the largest reported group of patients with BA complicated by SI who underwent a successful LDLT procedure. 相似文献
5.
6.
7.
Distortion and movement of the expander during skin expansion. 总被引:2,自引:0,他引:2
Masamitsu Kuwahara Mitsuo Hatoko Hideyuki Tada Aya Tanaka Satoshi Yurugi Kumi Mashiba 《Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi》2003,37(1):22-27
Distortion and movement of tissue expanders can cause expansion of the wrong area, such as the naevus or the scar that is to be resected. In 71 rectangular expanders, we examined the incidence of distortion (over 15 degrees) and movement (over 3 cm). We divided the expanders into three anatomical site groups: scalp, body, and extremities, and compared the complication rate between two study groups (distortion or movement, or not). In total, the incidence of distortion was 15/71 (21%) and that of movement 5/71 (7%). Distortion occurred mainly in the extremities (11/33,33%). The implanted expanders tended to move more often in the body part (3/15, 20%). In the extremities, the bigger the angle between the axis of the implanted expander and that of the extremity, the bigger the angle of distortion. Although the incidence of complications between the two groups was not significant, except for alteration in design of the flap, we recommend that these points should be considered when preoperative plans are being made for appropriate patients. 相似文献
8.
9.
We investigated the involvements of sympathetic and nonadrenergic nervous systems in the inhibitory reflex following bronchoconstriction in dogs. Inhalations of a 0.00125% solution of histamine and Ascaris suum antigen (3 mg protein) to the bronchial side induced reflex tracheal constriction following bronchoconstriction. An intra-arterial infusion of 5 micrograms/min of atropine to the tracheal site changed the reflex tracheal constrictions by histamine and antigen inhalations into tracheal dilatations. The reflex tracheal dilatations were abolished by the combination of intra-arterial propranolol (100 micrograms) and transections of both the bilateral superior laryngeal nerves and the spinal cord at the C1 level. The reflex tracheal constrictions induced by histamine and antigen inhalations were increased with 100 micrograms propranolol. Furthermore, the reflex tracheal constrictions were enhanced by the combination of 100 micrograms propranolol and transection of the spinal cord. These findings indicate that during the constriction of the bronchial smooth muscle, not only a reflex tracheal constriction mechanism but also one of reflex dilatation operates and that the latter reflex response may be mainly mediated by the sympathetic nerves, with partial involvement of the nonadrenergic nerves. This inhibitory reflex may attenuate asthmatic bronchoconstriction. 相似文献
10.