全文获取类型
收费全文 | 3594篇 |
免费 | 258篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 39篇 |
儿科学 | 212篇 |
妇产科学 | 72篇 |
基础医学 | 340篇 |
口腔科学 | 88篇 |
临床医学 | 313篇 |
内科学 | 859篇 |
皮肤病学 | 137篇 |
神经病学 | 193篇 |
特种医学 | 119篇 |
外国民族医学 | 1篇 |
外科学 | 633篇 |
综合类 | 77篇 |
现状与发展 | 1篇 |
一般理论 | 1篇 |
预防医学 | 237篇 |
眼科学 | 105篇 |
药学 | 231篇 |
中国医学 | 13篇 |
肿瘤学 | 194篇 |
出版年
2023年 | 40篇 |
2022年 | 80篇 |
2021年 | 140篇 |
2020年 | 96篇 |
2019年 | 131篇 |
2018年 | 133篇 |
2017年 | 107篇 |
2016年 | 112篇 |
2015年 | 132篇 |
2014年 | 176篇 |
2013年 | 222篇 |
2012年 | 279篇 |
2011年 | 256篇 |
2010年 | 133篇 |
2009年 | 140篇 |
2008年 | 206篇 |
2007年 | 198篇 |
2006年 | 213篇 |
2005年 | 183篇 |
2004年 | 148篇 |
2003年 | 140篇 |
2002年 | 124篇 |
2001年 | 59篇 |
2000年 | 41篇 |
1999年 | 38篇 |
1998年 | 16篇 |
1997年 | 13篇 |
1996年 | 15篇 |
1995年 | 14篇 |
1994年 | 7篇 |
1993年 | 10篇 |
1992年 | 16篇 |
1991年 | 17篇 |
1990年 | 13篇 |
1989年 | 15篇 |
1988年 | 20篇 |
1987年 | 12篇 |
1986年 | 16篇 |
1985年 | 15篇 |
1984年 | 18篇 |
1983年 | 12篇 |
1982年 | 7篇 |
1979年 | 8篇 |
1978年 | 9篇 |
1976年 | 10篇 |
1975年 | 7篇 |
1973年 | 13篇 |
1971年 | 6篇 |
1970年 | 6篇 |
1967年 | 6篇 |
排序方式: 共有3865条查询结果,搜索用时 15 毫秒
1.
2.
Qiaojie Wang Karan Goswami Noam Shohat Arash Aalirezaie Jorge Manrique Javad Parvizi 《The Journal of arthroplasty》2019,34(5):947-953
Background
Whether prolonged operative time is an independent risk factor for subsequent surgical site infection (SSI) and periprosthetic joint infection (PJI) following total joint arthroplasty (TJA) remains a clinically significant and underexplored issue. The aim of this study is to investigate the association between operative time and the risk of subsequent SSI and PJI in patients undergoing primary TJA.Methods
We retrospectively reviewed 17,342 primary unilateral total knee arthroplasty and total hip arthroplasty performed at a single institution between 2005 and 2016, with a minimum follow-up of 1 year. A multivariate logistic regression model was conducted to identify the association between operative time and the development of SSI within 90 days and PJI within 1 year.Results
Overall, the incidence of 90-day SSI and 1-year PJI was 1.2% and 0.8%, respectively. Patients with an operative time of >90 minutes had a significantly higher incidence of SSI and PJI (2.1% and 1.4%, respectively) compared to cases lasting between 60 and 90 minutes (1.1% and 0.7%), and those lasting ≤60 minutes (0.9% and 0.7%, P < .01). In the multivariate model, the risk for infection increased by an odds ratio of 1.346 (95% confidential interval 1.114-1.627) for 90-day SSI and 1.253 (95% confidential interval 1.060-1.481) for 1-year PJI for each 20-minute increase in operative time.Conclusion
In patients undergoing primary TJA, each 20-minute increase in operative time was associated with nearly a 25% increased risk of subsequent PJI. We advocate that surgeons pay close attention to this underappreciated risk factor while maintaining safe operative practices, which minimize unnecessary steps and wasted time in the operating room. 相似文献3.
Jennifer Novak Yujie Cui Paul Frankel Mina S. Sedrak Scott Glaser Richard Li Sabin Motwani Brian Kavanagh Arya Amini 《Practical radiation oncology》2021,11(3):e263-e266
PurposeTwitter is an increasingly popular social media platform within the health care community. The objective of this analysis is to characterize the profile of radiation oncology–related tweets and Twitter users over the past 6 years.Methods and MaterialsUsing the web-based social media analytics platform Symplur Signals, we filtered tweets containing at least 1 of the following hashtags or key words: #radonc, #radiationoncology, "rad onc," or "radiation oncology." We evaluated radiation oncology–related Twitter activity between October 2014 and March 2020 for tweet frequency, tweet content, and individuals or groups posting tweets. We identified the most influential Twitter users contributing to radiation oncology–related tweets.ResultsFrom 2014 to 2020, the quarterly volume of radiation oncology–related tweets increased from 5027 to 29,763. Physicians contributed the largest growth in tweet volume. Academic radiation oncologists comprise 60% of the most influential Twitter accounts responsible for radiation oncology–related content. The number of radiation-oncology resident physicians on Twitter increased from 25 to 328 over the past 6 years, and 20% of radiation-oncology residency programs have a Twitter account. Seventy-one percent of radiation oncology–related tweets generated direct communication via mentions, and 59% of tweets contain links to external sources, including scientific articles.ConclusionsThe number of physicians contributing radiation oncology–related Twitter content has increased significantly in recent years. Academic radiation oncologists are the primary influencers of radiation oncology–related Twitter activity. Twitter is used by radiation oncologists to both professionally network and discuss findings related to the field. There remains the opportunity for radiation oncologists to broaden their audience on Twitter to encompass a more diverse community, including patients. 相似文献
4.
ABSTRACT
Introduction
Immune checkpoint inhibitors (ICIs) have proved to be groundbreaking in the field of oncology. However, immune system overactivation from ICIs has introduced a novel medical entity known as immune-related adverse events (irAEs), that can affect any organ or tissue. ICI-induced inflammatory arthritis (ICI-IIA) is the most common musculoskeletal irAE and can lead to significant morbidity and limitation in anti-cancer therapy. 相似文献5.
Bagher Larijani Alireza Moayyeri Abbas Ali Keshtkar Arash Hossein-Nezhad Akbar Soltani Amir Bahrami Gholam Hossein Omrani Reza Rajabian Iraj Nabipour 《Journal of clinical densitometry》2006,9(3):367-374
Osteoporosis is a major public health problem in the Western countries and is projected to have a similar impact in the Middle East. It has been suggested that peak bone mineral density (BMD), a major determinant of osteoporotic fractures later in life, may be lower in this part of the world compared with the Western world. The purpose of the Iranian Multicenter Osteoporosis Study was to determine peak bone mass in a randomly chosen sample of healthy Iranian subjects. A total of 5201 participants (2340 males, mean age 42.7+/-13.8) were recruited based on randomized clustered sampling from all regions of five major cities across the country. In women, peak lumbar BMD (1.182+/-0.127 g/cm2) occurred in the 29- to 33-yr age group, whereas peak total femur BMD (1.006+/-0.126 g/cm2) occurred in the 32- to 36-yr age group. In men, peak lumbar BMD (1.181+/-0.153 g/cm2) and femoral BMD (1.096+/-0.159 g/cm2) both occurred in the 20- to 24-yr age group. When standardized to mg/cm2 units using established formulas, Iranian peak bone mass values are comparable with that of Western countries and are generally higher than that of Eastern Asian and Middle Eastern countries. 相似文献
6.
Tolerance of ocular iontophoresis in healthy volunteers. 总被引:4,自引:0,他引:4
Thomas M Parkinson Elizabeth Ferguson Salvatore Febbraro Arash Bakhtyari Martin King Mohan Mundasad 《Journal of ocular pharmacology and therapeutics》2003,19(2):145-151
To evaluate ocular tolerance, healthy volunteers were iontophoresed transclerally using novel OcuPhor trade mark hydrogel drug delivery applicators filled with balanced salt solution. In this three-period crossover study in 24 male and female subjects, 16 subjects received 0 mA and two of the following DC currents: 0.1, 0.5., 1.0, 2.0, 3.0, or 4.0 mA for 20 min; 6 subjects received 3 mA for 20 min and 1.5 mA for 40 min (both equivalent to 60 mAmin total charge). Safety and tolerance were determined by subjective VAS and objective ophthalmic assessments. Subjects were evaluated before and up to 22 hr after dosing. The applicators were well-tolerated and no clinically significant changes in symptomology or in ophthalmic assessments were seen following exposure to 0-3.0 mA for 20 min or 1.5 mA for 40 min. At 4.0 mA 2 of 4 subjects reported a burning sensation under the applicator during dosing which resolved by 22 hr post-dose; superficial changes in fluorescein staining were observed at 1 hr, but not at 22 hr. The OcuPhor trade mark system has promise for noninvasive drug delivery to the eye. 相似文献
7.
This communication highlights scleral dellen as an unusual complication of strabismus surgery in a 55-year-old hypertensive male. The clinical significance, differential diagnosis and management of this condition has been discussed. 相似文献
8.
9.
Hazards of smoking 总被引:1,自引:0,他引:1
A strong association exists between cigarette smoking and several diseases namely, cancer of the lung, bronchitis and emphysema, cancer of the larynx, oral cavity and oesophagus, gastric and duodenal ulcers, Crohn's disease, cancer of the bladder, coronary artery disease, macrocytosis, polycythaemia, leukaemia, etc. This is due to the harmful constituents of cigarette and other modalities smoking. Smokers not only harm themselves but also harm those around. Foetal malformations, abortions, stillbirths, prematurity and low birth weight are common in smoker mothers. These are the effects of passive smoking. There is no safer cigarette in the market even by lowering its harmful constituents. Mass education about the hazards of smoking with emphasis on complete stoppage of smoking is the only way to prevent its rising incidence. 相似文献
10.