全文获取类型
收费全文 | 3650篇 |
免费 | 200篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 81篇 |
儿科学 | 98篇 |
妇产科学 | 84篇 |
基础医学 | 562篇 |
口腔科学 | 59篇 |
临床医学 | 295篇 |
内科学 | 785篇 |
皮肤病学 | 77篇 |
神经病学 | 375篇 |
特种医学 | 155篇 |
外科学 | 249篇 |
综合类 | 24篇 |
预防医学 | 283篇 |
眼科学 | 65篇 |
药学 | 420篇 |
中国医学 | 10篇 |
肿瘤学 | 251篇 |
出版年
2024年 | 4篇 |
2023年 | 48篇 |
2022年 | 187篇 |
2021年 | 282篇 |
2020年 | 93篇 |
2019年 | 147篇 |
2018年 | 162篇 |
2017年 | 116篇 |
2016年 | 135篇 |
2015年 | 128篇 |
2014年 | 171篇 |
2013年 | 235篇 |
2012年 | 295篇 |
2011年 | 284篇 |
2010年 | 150篇 |
2009年 | 132篇 |
2008年 | 175篇 |
2007年 | 229篇 |
2006年 | 214篇 |
2005年 | 179篇 |
2004年 | 151篇 |
2003年 | 119篇 |
2002年 | 102篇 |
2001年 | 19篇 |
2000年 | 24篇 |
1999年 | 15篇 |
1998年 | 9篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 8篇 |
1992年 | 9篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1989年 | 4篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1978年 | 1篇 |
1976年 | 3篇 |
1975年 | 1篇 |
1972年 | 1篇 |
1969年 | 1篇 |
1967年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有3873条查询结果,搜索用时 15 毫秒
1.
Jakub Pazdrowski Aleksandra Daczak‐Pazdrowska Adriana Polaska Joanna Ka
mierska Wojciech Barczak Mateusz Szewczyk Pawe Golusiski Zygmunt Adamski Ryszard aba Wojciech Golusiski 《Skin research and technology》2019,25(6):857-861
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi‐quantitative clinical scores, which are not validated and may be subject to inter‐observer variability. A few previous studies suggested that high‐frequency ultrasonography (HF‐USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF‐USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF‐USG as well as dermatological assessment (target lesion score—TLS and CACE v. 4.0) were performed 4×: before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non‐irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P = .0002). There was no significant difference between non‐irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF‐USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy. 相似文献
2.
3.
Ohne Zusammenfassung 相似文献
4.
5.
6.
7.
Dariusz Marczak Aleksandra Rapa?a Monika Bekiesińska-Figatowska 《Chirurgia narzadów ruchu i ortopedia polska》2006,71(6):473-475
Transient osteoporosis of the hip is an uncommon disorder of unclear etiology. It is often confused with other diagnosis including osteonecrosis of the femoral head. Authors describe a case of transient osteoporosis of the hip of 32 years woman. The symptoms occurred in third trimester of pregnancy. The primary symptoms were right hip pain and decreased range of motion of the right hip. In diagnostic process helpful were clinical examination, X-ray, ultrasonography, MRI and microscopic examination. As a treatment authors used walking on crutches, calcitonin and calcium preparate. After a few months remission of symptoms and normalization in accessory investigations were obtained. 相似文献
8.
9.
Jovan P Antovic Marianne Yngen Claes-G?ran G Ostenson Aleksandra Antovic H?kan N Wallen Gun Jornesk?g Margareta Blomb?ck 《Blood coagulation & fibrinolysis》2003,14(6):551-556
We investigated thrombin activatable fibrinolysis inhibitor (TAFI) and its influence on fibrinolysis by measuring pro-TAFI activity and total TAFI antigen in 38 patients with type I diabetes mellitus (18 with and 20 without microvascular complications), as well as in 20 healthy controls. The pro-TAFI levels in the two groups of patients did not differ from those in the control group. Total TAFI antigen [i.e. pro-TAFI, TAFI and inactive carboxypeptidase U (TAFIi)] tended to decrease in both the patient groups (59.7 +/- 7.2 and 73.4 +/- 8.9% with and without microvascular complications, respectively) compared with controls (91.9 +/- 12.2%) (P = 0.12). We also assessed the overall hemostatic potential (OHP) in plasma, the clot lysis time and the overall fibrinolytic potential. The OHP was significantly higher in patients with complications compared with controls (8.9 +/- 0.9 versus 6.7 +/- 0.4; P < 0.05) and also higher in the diabetics without complications (7.8 +/- 0.6), although the latter difference did not reach statistical significance. Levels of clot lysis time and overall fibrinolytic potential were similar in the two groups of patients and the controls. The increased OHP in plasma from diabetic patients with microvascular complications indicates an imbalance of the hemostatic system towards a prothrombotic state. No signs of impaired fibrinolysis were observed in patients with diabetes. Using the OHP method for estimation of overall hemostasis, it seems that TAFI does not influence either fibrinolysis or the increased thrombotic potential observed in patients with type I diabetes mellitus. 相似文献
10.
Norbert Rilinger Johannes Görich Reinhard Scharrer-Pamler Jochen Vogel Reinhard Tomczak Elmar Merkle Roman Sokiranski Hans-Jürgen Brambs 《Cardiovascular and interventional radiology》1997,20(4):263-267
Purpose To evaluate the clinical results of percutaneous transluminal rotational atherectomy in the treatment of peripheral vascular
disease.
Methods Rotational atherectomy was performed in 39 patients aged 39–87 years (mean 66.6 years). A total of 71 lesions (43 stenoses
and 28 occlusions) were treated in 40 limbs. Additional balloon angioplasty was required in 54% of lesions. Fifteen patients
(37.5%) presented in Fontaine stage II, 10 patients (25%) in Fontaine stage III and 15 patients (37.5%) in Fontaine stage
IV. Rotational atherectomy at 750 rpm was carried out over a 0.014-inch guidewire with continuous aspiration into a vacuum,
bottle. Follow-up angiography and color flow Doppler examinations were performed in 22 patients (23 limbs) after a mean period
of 6 months (range 2–14 months)
Results There was one primary technical failure. In 36 of 40 lesions there was a good angiographic result with residual stenoses in
less than 30%. In 70 lesions treated by rotational atherectomy, however, 54% showed residual stenoses of 30%–50% and these
cases required additional balloon angioplasty. The mean ankle-brachial index improved significantly (p<0.001), from 0.49 before the procedure to 1.01 after the procedure. A single distal embolus, related to primary recanalization,
occurred and there were two large inguinal hematomas. Cumulative clinical patency after 6 months was 83.8% and cumulative
angiographic patency after 6 months was 79.1%.
Conclusion Percutaneous rotational atherectomy is a promising approach for the treatment of chronic peripheral vascular disease. Further
prospective, randomized studies are necessary to compare percutaneous transluminal angioplasty with this new technical approach. 相似文献