全文获取类型
收费全文 | 4549篇 |
免费 | 245篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 29篇 |
儿科学 | 228篇 |
妇产科学 | 132篇 |
基础医学 | 656篇 |
口腔科学 | 66篇 |
临床医学 | 381篇 |
内科学 | 984篇 |
皮肤病学 | 73篇 |
神经病学 | 274篇 |
特种医学 | 110篇 |
外科学 | 457篇 |
综合类 | 102篇 |
一般理论 | 4篇 |
预防医学 | 276篇 |
眼科学 | 163篇 |
药学 | 517篇 |
1篇 | |
中国医学 | 58篇 |
肿瘤学 | 306篇 |
出版年
2023年 | 25篇 |
2022年 | 70篇 |
2021年 | 140篇 |
2020年 | 70篇 |
2019年 | 106篇 |
2018年 | 128篇 |
2017年 | 72篇 |
2016年 | 114篇 |
2015年 | 124篇 |
2014年 | 138篇 |
2013年 | 229篇 |
2012年 | 342篇 |
2011年 | 334篇 |
2010年 | 215篇 |
2009年 | 134篇 |
2008年 | 298篇 |
2007年 | 287篇 |
2006年 | 252篇 |
2005年 | 252篇 |
2004年 | 207篇 |
2003年 | 218篇 |
2002年 | 175篇 |
2001年 | 73篇 |
2000年 | 83篇 |
1999年 | 62篇 |
1998年 | 31篇 |
1997年 | 28篇 |
1996年 | 31篇 |
1995年 | 20篇 |
1994年 | 19篇 |
1993年 | 18篇 |
1992年 | 41篇 |
1991年 | 34篇 |
1990年 | 37篇 |
1989年 | 33篇 |
1988年 | 24篇 |
1987年 | 25篇 |
1986年 | 27篇 |
1985年 | 22篇 |
1984年 | 25篇 |
1983年 | 15篇 |
1981年 | 17篇 |
1979年 | 13篇 |
1978年 | 16篇 |
1976年 | 22篇 |
1974年 | 14篇 |
1973年 | 16篇 |
1972年 | 14篇 |
1970年 | 15篇 |
1969年 | 14篇 |
排序方式: 共有4817条查询结果,搜索用时 15 毫秒
1.
Malunguja Gisandu K. Devi Ashalata 《Proceedings of the National Academy of Sciences, India. Section B.》2022,92(1):105-120
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Heavy metal concentrations in surface soils of Reserved Forests (RFs) have a significant impact on... 相似文献
2.
3.
Wendy Packman Joselyn Fine Beth Chesterman Kelly vanZutphen Rama Golan Michael Amylon 《Children's Health Care》2004,33(3):201-215
This research was conducted at a summer camp for siblings of children with cancer. The camp is designed to address emotional problems, provide peer interaction and validation, and bolster siblings' self-esteem. Standardized measures assessing posttraumatic stress, anxiety, quality of life, and self-esteem were administered to 77 siblings (ages 6-17) prior to attending camp and again 3 months after camp. From pre- to post-camp, the siblings reported statistically significant decreases in symptoms of posttraumatic stress and anxiety, and statistically significant improvements in quality of life and self-esteem. These preliminary findings are encouraging and suggest the value of camp as a psychological intervention and provide a model for other pediatric cancer facilities designing intervention programs for siblings. 相似文献
4.
5.
6.
Devi Kanikanti Padmalatha Rao Kanikanti V. Ranga Baveja Srikrishan Fathi Marc Roth Marc 《Pharmaceutical research》1989,6(4):313-317
Zero-order release of oxprenolol hydrochloride was obtained by controlling the swelling and erosion of the matrix. This formulation involves only mixing of drug, hydroxypropylmethylcellulose (HPMC), and sodium carboxymethylcellulose (Na CMC) at the ratio of 1:0.4:1.6, respectively, and compressing the mixture directly into tablets. The in vitro release pattern from this optimized matrix tablet was reproducible. Accelerated stability studies revealed that the optimized formulation remains stable for an approximately 2-year shelf life. This sustained-release (SR) tablet was evaluated in dogs, and for comparison a conventional (CV) formulation was also given at the same dose level. Plasma oxprenolol levels were monitored by a sensitive and specific high-performance liquid chromatographic (HPLC) method. Significant differences in the pharmacokinetic parameters, i.e., lower C
max, higher values of t
max, MRT, AUC, and plasma concentration at 24 hr, and nearly constant plasma levels over 12 hr, indicated that the SR matrix tablet is superior to the CV rapid-releasing formulation. The in vitro release parameters and in vivo pharmacokinetics correlated well. 相似文献
7.
Emmanuel Lansac Isabelle Di Centa Nicolas Bonnet Pascal Leprince Akthar Rama Christophe Acar Alain Pavie Iradj Gandjbakhch 《European journal of cardio-thoracic surgery》2006,29(4):537-544
OBJECTIVE: Dilation of aortic annulus, sinuses of Valsalva, and sinotubular junction (STJ) diameters are the characteristic lesions of aortic root aneurysm. The remodeling technique reduces STJ diameter and creates three neosinuses of Valsalva. Alternatively, the reimplantation technique reduces both annulus and STJ diameters to the detriment of aortic root dynamics. Although the remodeling technique is recognized as the most physiological valve-sparing procedure, aortic annulus dilation may jeopardize its results. A standardized approach that combines an external subvalvular aortic prosthetic ring annuloplasty with the remodeling technique is suggested. METHODS: Eighty-three patients underwent an elective aortic root remodeling procedure, either isolated (group 1, n=34) or combined with an external subvalvular aortic prosthetic ring annuloplasty (group 2, n=49). Preoperative aortic regurgitation was 1.59+/-1.1 (group 1) and 1.97+/-1.3 (group 2) (NS). The aortic annulus was more dilated in group 2 than in group 1 (27+/-2.77 mm vs 26.4+/-2.3 mm, p<0.01). Residual aortic regurgitation > or =grade II was the conversion criteria for aortic valve replacement. RESULTS: Operative mortality was 3.6% (n=3). Intraoperative conversion for valve replacement was 32.7% in group 1 (n=11) versus 4.2% in group 2 (n=2) (p<0.001). In group 1, preoperative annulus diameter was larger for converted than for valve-spared patients (27.6+/-1.7 mm vs 25.2+/-1.5 mm, p<0.02). In group 2, implanted aortic ring significantly reduced annulus diameter (20.6+/-1.8 mm) without significant aortic valve gradient (8.3+/-3 mmHg). Follow-up was 17.2+/-13.4 months (group 1) and 10.41+/-7.95 months (group 2). Reoperation for recurrent aortic regurgitation was 13% in group 1 (n=3) versus 4.2% in group 2 (n=2). Echocardiographic follow-up found residual aortic regurgitation < or =grade I in 17 patients in group 1 (90%) versus 43 patients in group 2 (95.5%) and of grade II in two patients in group 1 (10%) and two patients in group 2 (4.5%). CONCLUSION: The addition of external aortic prosthetic ring annuloplasty improves the remodeling technique's operative reproducibility and short-term results. Therefore, its use as a systematical adjunct to the remodeling procedure is suggested. However, further long-term evaluation comparing this valve-sparing procedure to composite graft replacement should define the best surgical strategy for aortic root aneurysm. 相似文献
8.
A K Rama Krishna Shivanand Patil Grs Srinivas Rao Ajit Kumar 《Indian journal of gastroenterology》2006,25(2):97-98
Gastrointestinal manifestations of dengue fever are mainly in the form of bleeding or liver function abnormalities. Dengue fever presenting as acute colitis-like picture is not reported to date. We report a 50-year-old man with dengue fever presenting with lower gastrointestinal bleeding and colonoscopic features of acute inflammatory colitis. 相似文献
9.
M Devi S Nalin Kumar K Ranganathan T R Saraswathi 《Indian journal of dental research》2004,15(4):149-151
Intravascular papillary endothelial hyperplasia (IPEH) is an unusual vascular lesion of proliferating endothelial cells. It is more frequently seen in the extremities, particularly in the fingers. Oral IPEH has been reported with the common sites being lip, tongue, and buccal mucosa. In this article, we present a case of oral IPEH of the floor of the mouth, an unusual location, presenting in a 9-month-old male. The histogenesis, histologic features, and ultrastructural features are also reviewed. A misdiagnosis of angiosarcoma can be made in a case of IPEH due to similar histopathologic features. It is imperative to rule out this error by an elaborate histopathologic evaluation ofthese lesions. 相似文献
10.
118 multibacillary leprosy patients with differential manifestations were studied for the antigens they expressed at MHC loci to investigate the role of human leukocyte antigens in the differential response to the same causative agent. While the lepromatous leprosy (LL) patients showed a significant increase of Bw60, DR2, DRw8 and DQw1, borderline lepromatous (BL) patients had Bw52, DR9 and DQw7 significantly more often as compared to the normal controls. A comparison of LL, BL and mid-borderline (BB) patients showed a significantly higher frequency of Bw60 in LL patients as compared to the BL. However, Bw52, Bw53, DR9 and DQw7 were found significantly more often in the BL patients as compared to the LL patients but the difference failed to reach significance after pc. A comparison of HLA antigens in BB patients with those of either the LL or BL patients did not show any significant differences. 相似文献