全文获取类型
收费全文 | 2911篇 |
免费 | 147篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 33篇 |
儿科学 | 27篇 |
妇产科学 | 97篇 |
基础医学 | 434篇 |
口腔科学 | 23篇 |
临床医学 | 248篇 |
内科学 | 611篇 |
皮肤病学 | 34篇 |
神经病学 | 267篇 |
特种医学 | 189篇 |
外科学 | 404篇 |
综合类 | 17篇 |
一般理论 | 2篇 |
预防医学 | 107篇 |
眼科学 | 141篇 |
药学 | 172篇 |
中国医学 | 8篇 |
肿瘤学 | 251篇 |
出版年
2023年 | 23篇 |
2022年 | 42篇 |
2021年 | 52篇 |
2020年 | 40篇 |
2019年 | 42篇 |
2018年 | 56篇 |
2017年 | 33篇 |
2016年 | 65篇 |
2015年 | 64篇 |
2014年 | 88篇 |
2013年 | 116篇 |
2012年 | 163篇 |
2011年 | 183篇 |
2010年 | 108篇 |
2009年 | 117篇 |
2008年 | 169篇 |
2007年 | 178篇 |
2006年 | 169篇 |
2005年 | 182篇 |
2004年 | 168篇 |
2003年 | 186篇 |
2002年 | 166篇 |
2001年 | 52篇 |
2000年 | 43篇 |
1999年 | 71篇 |
1998年 | 24篇 |
1997年 | 34篇 |
1996年 | 32篇 |
1995年 | 20篇 |
1994年 | 16篇 |
1993年 | 10篇 |
1992年 | 27篇 |
1991年 | 24篇 |
1990年 | 15篇 |
1989年 | 15篇 |
1988年 | 13篇 |
1987年 | 9篇 |
1986年 | 13篇 |
1985年 | 15篇 |
1984年 | 12篇 |
1983年 | 11篇 |
1982年 | 12篇 |
1981年 | 7篇 |
1979年 | 16篇 |
1977年 | 14篇 |
1975年 | 12篇 |
1974年 | 12篇 |
1973年 | 17篇 |
1972年 | 7篇 |
1971年 | 9篇 |
排序方式: 共有3065条查询结果,搜索用时 0 毫秒
1.
Interprofessional collaboration and communication in nursing homes: a qualitative exploration of problems in medical care for nursing home residents – study protocol
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
2.
Edward M Messing Judith Manola George Wilding Kathleen Propert Jonathan Fleischmann E David Crawford J Edson Pontes Richard Hahn Donald Trump 《Journal of clinical oncology》2003,21(7):1214-1222
PURPOSE: To evaluate the role of adjuvant interferon alfa after complete resection of locally extensive renal cell carcinoma. PATIENTS AND METHODS: A total of 283 eligible patients with pT3-4a and/or node-positive disease were randomly assigned after radical nephrectomy and lymphadenectomy to observation or to interferon alfa-NL (Wellferon, Burroughs-Wellcome, Research Park, NC) given daily for 5 days every 3 weeks for up to 12 cycles. Patients were stratified on the basis of pathologic stage. Patients remained on treatment until documented recurrence, excessive toxicity, or patient/physician preference deemed removal appropriate. RESULTS: At median follow-up of 10.4 years, median survival was 7.4 years in the observation arm and 5.1 year in the treatment arm (log-rank P =.09). Median recurrence-free survival was 3.0 years in the observation arm and 2.2 years in the interferon arm (P =.33). Performance status (P =.003), nodal status (N2 v N0, P <.0001), and tumor stage (P =.0002) were significant prognostic factors in multivariate analysis. A proportional hazards model examining the effects of treatment arm and time to recurrence on survival after recurrence among patients who recurred found that random assignment to interferon treatment (P =.009) and shorter time to recurrence (P <.0001) were independent predictors of shorter survival after recurrence. Although no lethal toxicities were observed, severe (grade 4) toxicities including neutropenia, myalgia, fatigue, depression, and other neurologic toxicities occurred in 11.4% of those randomly assigned to interferon treatment. CONCLUSION: Adjuvant treatment with interferon did not contribute to survival or relapse-free survival in this group of patients. 相似文献
3.
4.
Martin A Ritter Achim Frese Rainer Dziewas Stefan Knecht Stefan Evers 《Movement disorders》2006,21(10):1787-1788
Synkinesias secondary to nerve lesions and aberrant re-innervation are well-known phenomena especially after lesions of the facial nerve. Synkinesias can successfully be treated with botulinum toxin A (BTx A). Synkinesias of the cremaster muscle have not been described or treated to date. We present the case of a 62-year-old man who developed synkinesias of both cremaster muscles after extensive laparatomy for esophageal cancer. Treatment of synkinesias with various oral medications had been unsuccessful. Electromyography-guided injections of BTx A in both cremaster muscles (15 MU on the right and 10 on the left) led to significant symptom relief for an average of 8 weeks. We present the case including pre- and posttreatment video clips. 相似文献
5.
Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes. 总被引:2,自引:0,他引:2
Christian Delles Markus P Schneider Sebastian Oehmer Ingrid Fleischmann Erwin F Fleischmann Roland E Schmieder 《Nephrology, dialysis, transplantation》2004,19(10):2513-2518
BACKGROUND: Reactive oxygen species play a major role in the development of endothelial dysfunction. It is as yet unspecified whether increased oxidative stress contributes to endothelial dysfunction of the renal vasculature in patients with type 2 diabetes. METHODS: Renal haemodynamics were studied in 20 patients with type 2 diabetes and arterial hypertension (age 62 +/- 5 years) and 20 non-diabetic hypertensive patients at baseline and following infusions of the nitric oxide synthase inhibitor, N(G)-monomethyl-L-arginine (L-NMMA; 4.25 mg/kg); the substrate of nitric oxide synthase, L-arginine (100 mg/kg); and the antioxidant, vitamin C (3 g, co-infused with L-arginine 100 mg/kg). RESULTS: The response of renal plasma flow (RPF) to L-NMMA (-54 +/- 62 and -45 +/- 42 ml/min/1.73 m(2); P = NS) and L-arginine (+46 +/- 36 and +49 +/- 25 ml/min/1.73 m(2); P = NS) was not different between diabetic and non-diabetic patients. In contrast, vitamin C induced a more pronounced increase in RPF in diabetic than in non-diabetic patients when co-infused with L-arginine (+71+/-47 and +43+/-33 ml/min/1.73 m(2); P<0.05). CONCLUSIONS: The difference in the response of renal perfusion to an antioxidant suggests increased formation of reactive oxygen species and thereby reduced nitric oxide bioavailability in the renal vasculature of patients with type 2 diabetes. 相似文献
6.
7.
U M Fleischmann 《Zeitschrift für Gerontologie》1988,21(3):150-155
Based on a sample of N = 145 subjects, 57 to 96 years of age, the generation-recognition model of recall (12) was investigated. Using standardized word lists, a differential effect of the word frequency on free recall and recognition is shown. The assumption of separate processes in free recall is thus confirmed. The difference score from recognition and recall is shown to be age-independent and difficult to interpret as retrieval score in the framework of other performance measures. 相似文献
8.
9.
10.