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Durga Prasanna Misra Abhra Chandra Chowdhury Hira Lal Namita Mohindra Vikas Agarwal 《Rheumatology international》2016,36(3):449-453
Takayasu’s arteritis (TA) is a granulomatous large vessel vasculitis more commonly seen in India. The vascular inflammation in TA results in stenoses of affected vessels. Usually this is a slow process with good collateral circulation; only rarely does critical limb ischemia result. We present two patients of TA who presented with gangrene of extremities, and review eight prior such patients reported in the literature. With appropriate diagnosis and treatment with oral corticosteroids and low-dose aspirin, none of our patients had recurrence at a mean follow-up of 3.8 ± 2.8 years. Although rare, TA can present with gangrene and rheumatologists need to be aware of this unusual but limb-threatening manifestation of TA to institute appropriate therapy in a timely manner. 相似文献
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Durga Prasanna Misra Abhra Chandra Chowdhury Sanat Phatak Vikas Agarwal 《World Journal of Rheumatology》2015,5(3):131-141
Scleroderma (or systemic sclerosis) is a rare disease associated with significant morbidity and mortality. Although previously thought to have a uniformly poor prognosis, the outlook has changed in recent years. We review recent insights into the pathogenesis, clinical features, assessment and management of scleroderma. 相似文献
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Multiple myeloma masquerading as severe seropositive rheumatoid arthritis with subcutaneous nodules and mononeuritis multiplex
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Sukesh Edavalath Abhra C. Chowdhury Sanat Phatak Durga P. Misra Ritu Verma Able Lawrence 《International journal of rheumatic diseases》2017,20(9):1297-1302
Multiple myeloma can rarely mimic seronegative rheumatoid arthritis (RA). We report a 55‐year‐old woman who presented with longstanding deforming polyarthritis with extensive subcutaneous nodules, tenosynovitis, anti‐cyclic citrullinated peptide positivity and mononeuritis multiplex. Even though the clinical picture was consistent with seropositive RA, the absence of bone erosion or joint space narrowing on hand and knee radiographs led us to question the diagnosis of RA. Further investigation revealed a diagnosis of multiple myeloma with cutaneous amyloid deposits, based on serum immunofixation, bone marrow aspiration and biopsy of a subcutaneous nodule. The only clue to suspect myeloma from the basic investigations and clinical examination was mild hypercalcemia. This case serves to reiterate the need to maintain a heightened suspicion for other diagnoses even when RA appears most likely. 相似文献
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Shaher Sania Chanda Abhra Hazra Sugata Mukherjee Ananda Deb 《Proceedings of the National Academy of Sciences, India. Section B.》2019,89(4):1133-1139
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Wetlands are amongst the most important natural ecosystems on earth. India is blessed to have several... 相似文献
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