全文获取类型
收费全文 | 386篇 |
免费 | 23篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 10篇 |
妇产科学 | 10篇 |
基础医学 | 24篇 |
口腔科学 | 5篇 |
临床医学 | 14篇 |
内科学 | 89篇 |
皮肤病学 | 1篇 |
神经病学 | 10篇 |
特种医学 | 6篇 |
外科学 | 164篇 |
综合类 | 6篇 |
预防医学 | 13篇 |
眼科学 | 6篇 |
药学 | 18篇 |
中国医学 | 2篇 |
肿瘤学 | 29篇 |
出版年
2023年 | 3篇 |
2022年 | 12篇 |
2021年 | 13篇 |
2020年 | 8篇 |
2019年 | 17篇 |
2018年 | 23篇 |
2017年 | 7篇 |
2016年 | 12篇 |
2015年 | 13篇 |
2014年 | 46篇 |
2013年 | 31篇 |
2012年 | 59篇 |
2011年 | 53篇 |
2010年 | 19篇 |
2009年 | 10篇 |
2008年 | 12篇 |
2007年 | 4篇 |
2006年 | 6篇 |
2005年 | 9篇 |
2004年 | 6篇 |
2003年 | 3篇 |
2002年 | 5篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 3篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1990年 | 5篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1985年 | 1篇 |
1984年 | 4篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1977年 | 1篇 |
1975年 | 1篇 |
1974年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1963年 | 1篇 |
排序方式: 共有410条查询结果,搜索用时 0 毫秒
1.
N-acetylcysteine does not modify nitroglycerin-induced tolerance in canine vascular rings 总被引:2,自引:0,他引:2
The mechanism whereby nitroglycerin initiates relaxation in vascular smooth muscle remains unclear. One hypothesis states that nitroglycerin oxidizes critical sulfhydryl groups in smooth muscle to initiate relaxation, and that repeated exposure to nitroglycerin results in tolerance. In the current study, N-acetylcysteine, a sulfhydryl-reducing agent, was used to explore the sulfhydryl hypothesis by assessing whether or not tolerance to nitroglycerin was reversed by N-acetylcysteine in canine dorsal pedal artery rings. Two nitroglycerin dose-response curves were performed (n = 18)--one before (1st dose-response curve, from 10(-9) to 1.1 X 10(-5) M nitroglycerin) and one after (2nd dose-response curve, from 10(-9) to 5 X 10(-7) M nitroglycerin) incubation with 10(-5) M nitroglycerin for 105 min. At 5 X 10(-7) M nitroglycerin there was 50.7 +/- 10.0% relaxation during the first dose-response curve. During the second dose-response curve, tolerance to nitroglycerin was evident, as demonstrated by a 6.8 +/- 4.8% relaxation (p less than 0.001) at 5 X 10(-7) M nitroglycerin. A 10-min treatment with 10(-3) M N-acetylcysteine (n = 10) during the second nitroglycerin dose-response curve was performed after the 5 X 10(-7) M concentration of nitroglycerin; the second dose-response curve was then completed up to 1.1 X 10(-5) M nitroglycerin. The dose of 10(-3) M N-acetylcysteine was chosen since higher concentrations (i.e., 1.3 X 10(-2) and 1.2 X 10(-1) M N-acetylcysteine) produced 20.3 +/- 8.4 and 43.6 +/- 11.6% relaxation in vascular rings (n = 5).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
2.
Firas Abdollah Maxine Sun Alberto Briganti Pierre Karakiewicz 《BJU international》2012,109(12):E44-E45
3.
Fereydoon Abedini Abdollah Ahmadi Akram Yavari Sarah Mousavi 《International wound journal》2013,10(5):573-578
The study aims to perform a comparative assessment of two types of burn wound treatment. To do the assessment, patients with partial thickness burn wounds with total body surface area <40% were simple randomised to treat with nanocrystalline silver nylon wound dressing or silver sulfadiazine cream. Efficacy of treatment, use of analgesics, number of wound dressing change, wound infection and final hospitalisation cost were evaluated. The study showed silver nylon wound dressing significantly reduced length of hospital stay, analgesic use, wound infection and inflammation compared with silver sulfadiazine. 相似文献
4.
5.
6.
7.
8.
9.
10.
Lasers in Medical Science - The primary goal of this systematic review article was to provide an outline of the use of diabetic autologous adipose-derived mesenchymal stem cells (DAAD-MSCs) in the... 相似文献