肿瘤患者确诊时信息需求的调查分析

我们对 5 0 0例患者进行了有关肿瘤诊断信息需求的调查 ,现将调查结果报告如下。1　调查对象及方法1.1　调查对象。 2 0 0 0年 8～ 12月在我院住院的 5 0 0例患者 ,经病理确诊全部为恶性肿瘤。其中男 32 0例 ,女 180例 ,年龄 2 3～ 78岁。学历 :高中及以上 2 78例 ,初中及以下2 2 2例。职业 :干部 15 5例 ,工人 10 7例 ,农民 12 7例 ,个体户6 4例 ,其他 4 7例。1.2　方法。采用自行设计的问卷调查。问卷除患者一般资料外主要有 8方面内容 :你认为医生应否告知病人肿瘤诊断 ;医生应否告知其可能生存时间 ;谁告知患者肿瘤诊断最好 ;应以何种方…     

PEG/PLGA纳米纤维膜的制备及其参数优化

通过静电纺丝法制备的聚乳酸-羟基乙酸共聚物(PLGA)纳米纤维膜是一种具有广阔应用前景的医用可生物降解高分子材料.为探究不同因素对纺丝过程及膜力学性能的影响,本研究采用响应面法中Box-Behnken设计,选取了PEG含量、纺丝速度和电压3个因素作为影响因子,以拉伸强度作为考察对象,通过回归分析建立了二次多元模型.结果表明,PEG含量对力学性能的影响最为显著,其次为电压的二次项;模型预测的拉伸强度值与真实值能较好的拟合,说明该模型能有效地预测PEG/PLGA复合纤维膜的力学性能.     

可吸收防粘连膜的应用研究与未来展望北大核心

BACKGROUND: Postoperative tissue adhesions can cause serious complications, resulting in the loss of body function, which deeply affects the patient's quality of life, and brings great threat to the life and health. Therefore, it is necessary to prevent postoperative tissue adhesion. OBJECTIVE: To summarize the achievement of absorbable anti-adhesion membrane in recent years, and to gain further insight into its advantages and disadvantages. METHODS: PubMed and CNKI were searched for relevant articles about anti-adhesion materials or products published from 2005 to 2016. The key words were “absorbable membrane, absorbability, anti-stiction, anti-adhesion, electrospinning, electrospun, nano-fiber, anti adhesion membrane/film, biodegradability” in Chinese and English, respectively. In accordance with the inclusion and exclusion criteria, 42 articles were reviewed. RESULTS AND CONCLUSION: Anti-adhesion membranes can effectively prevent postoperative adhesions, accelerate wound healing, and improve patients' quality of life. Bio-films, prepared using the film casting method, have the shortcomings of brittleness and poor toughness, which limit its clinical application. However, the anti-adhesion membrane made by electrostatic spinning technology has the advantages of high plasticity and good adhesiveness. It not only has the function of preventing adhesion, but also has a good biocompatibility during the tissue healing process. More fortunately, it can be degraded or absorbed in the postoperative period, showing its potential advantages. Nano-fiber products prepared by electro-spinning technology possess excellent characteristics, such as specific surface-area, high porosity, strong adsorption, fine fibrousness, excellent mechanical properties and so on, which have attracted much attention in the biomedical field. Such products have been also widely used in wound repair, tissue engineering and absorbable anti-adhesion membranes. [ABSTRACT FROM AUTHOR]