心室肌脂肪:一个意想不到的远期生存生物标志物?

正目的非增强CT常常观察到心肌脂肪,但对其认识不足,本文旨在探究心肌内脂肪与全因死亡率的关系,无论是否有心肌梗死病史。方法本回顾性队列研究收集了不     

穴位贴敷诱发的急、慢性接触性皮炎皮损特点及胸腺基质淋巴细胞生成素的表达差异性

目的观察穴位贴敷诱发的急性接触性皮炎与慢性接触性皮炎皮损特点以及皮损内胸腺基质淋巴细胞生成素(thymal stromal,tymphopoietin,TSLP)表达的差异性。方法选取三伏天接受穴位贴敷治疗哮喘且诱发急性或慢性接触性皮炎的患者20例,取皮分为急性接触性皮炎组(简称急性组)和慢性接触性皮炎组(简称慢性组),观察两组患者皮损特点及皮损组织中TSLP表达的差异性。结果急性组有大量的TSLP分布,弥漫性分布在表皮层(角质层、颗粒层、棘层和基底层)以及真皮层血管周围;慢性组TSLP数量较急性组少,集中分布在表皮层的角质层、棘层以及真皮层血管周围。结论 TSLP在穴位贴敷诱发的急性接触性皮炎与慢性接触性皮炎中的分布具有明显的数量差异性,而分布部位差异性不明显。推测皮炎性质(急性或慢性)会影响穴位贴敷疗效,而TSLP可以作为一个监测指标。     

美国≥65岁女性的数字二维乳腺摄影与断层成像对比

正摘要虽然乳腺癌的发病率和死亡率随着年龄的增长而增加,但有关老年妇女筛查乳腺X线检查的益处和风险,以及老年妇女二维数字乳腺X线摄影(DM)和数字乳腺断层成     

Significant impact of cryopreserved amniotic membrane on acute ocular Stevens-Johnson syndrome and toxic epidermal necrolysis

The ocular surface is covered by an epithelium encompassing an area including the cornea,the limbus and the conjunctiva bordered by the upper and lower lids.The healthy state of the ocular surface epithelium depends on a stable and protective preocular tear film when the eye is open.A stable preocular tear film is governed by sound ocular surface defense that involves effective neuroanatomic integration of compositional and hydrodynamic factors by two neural reflexes (1).     

护理干预对改善心内科住院患者睡眠质量的作用分析

目的：探讨护理干预在改善心内科住院患者睡眠质量方面的应用效果。方法：选取在我院接诊的65例心内科住院患者，其接受整体护理，设为观察组，回顾性分析早期在我院接诊的64例心内科住院患者的临床资料，其接受常规护理，设为对照组。通过调查问卷的方法了解两组心内科住院患者的护理满意度。结果：在接受不同护理情况下，观察组、对照组心内科住院患者的护理满意度分别为93．84％、78．12％，差异较大，有统计学意义。结论：护理干预能够有效改善心内科住院患者的睡眠质量，值得临床推广和应用。     

Glial regenerative response in the imaginal discs of Drosophila melanogaster

<正>Glial cells play a key role during nervous system development and actively participate in all the cellular processes involved in maintaining its structural robustness and functional plasticity.In response to neuronal damage,glial cells proliferate,migrate to the injured region and change their morphology,function,and behavior     

Tandem pore TWIK-related potassium channels and neuroprotection

TWIK-related potassium channels(TREK) belong to a subfamily of the two-pore domain potassium channels family with three members, TREK1, TREK2 and TWIK-related arachidonic acid-activated potassium channels. The two-pore domain potassium channels is the last big family of channels being discovered, therefore it is not surprising that most of the information we know about TREK channels predominantly comes from the study of heterologously expressed channels. Notwithstanding, in this review we pay special attention to the limited amount of information available on native TREK-like channels and real neurons in relation to neuroprotection. Mainly we focus on the role of free fatty acids, lysophospholipids and other neuroprotective agents like riluzole in the modulation of TREK channels, emphasizing on how important this modulation may be for the development of new therapies against neuropathic pain, depression, schizophrenia, epilepsy, ischemia and cardiac complications.     

多参数MR成像全肿瘤直方图分析三阴性乳腺癌与其他亚型的鉴别

正摘要目的利用多参数MR成像图谱和全肿瘤直方图分析三阴性(TN)乳腺癌与其他分子亚型鉴别的影像学生物标志。方法本回顾性研究包括134例浸润性导管癌病人。从     

慢性血栓栓塞性肺动脉高压病人在球囊血管成形术前后的肺灌注血容量CT、肺灌注SPECT、肺血管造影的临床及预测价值比较

正摘要目的使用双能量CT计算肺灌注血容量(PBV)诊断肺血栓栓塞已被广泛接受。本研究评价慢性血栓栓塞性肺高压(CTEPH)病人在球囊肺血管成形术(BPA)前、后的肺