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目的评价放松纯净α音乐对重症急性胰腺炎(severe acute pancreatitis,SAP)患者的情绪调节作用,探求音乐疗法在SAP中的价值。方法收集SAP患者82例,随机分为2组,每组41例。治疗组在常规治疗的基础上加用放松纯净α音乐、对照组仅采用常规治疗,疗程14 d,测定患者治疗前后SAS、SDS评分,以及2组患者的住院时间、腹痛缓解时间,评价疗效。结果在常规治疗的基础上联合放松纯净α音乐可有效降低SAP患者SAS、SDS评分,缩短腹痛缓解时间及住院时间,差异有统计学意义(P<0.05)。结论放松纯净α音乐对SAP患者可起到有效的情绪调节功能,良好的心理状态可更好的促进疾病恢复,值得临床推广使用。 相似文献
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BACKGROUND:Gastric cancer stem cells involved in the neoadjuvant chemotherapy and conventional treatment are closely associated with relapse of gastric cancer. However, this conclusion has not yet been confirmed.
OBJECTIVE:To investigate the effects of gastric cancer stem cells in tumor invasion and metastasis and its effect on angiogenesis ability.
METHODS:We prepared nude mouse models of gastric cancer to isolate and culture gastric cancer stem cells. Harvested gastric cancer stem cells were detected in cell scratch test, ring test, inhibition rate test, cell migration test and tumorigenicity test.
RESULTS AND CONCLUSION:After 7 days of culture, the cells exhibited adherent growth but a lack of regularity that most cells were in a tadpole shape. In the cell scratch test, the scratch width was significantly different at 0 and 24 hours (P < 0.05). Under an inverted microscope, the cells were found to form a ring in the ring test. The 50% inhibiting concentration of gastric cancer stem cells induced by oxaliplatin was significantly lower than that induced by 5-fluorouracil (P < 0.05). The number of cells passing through the basilar membrane was significantly increased after cell migration (P < 0.05). After implantation of gastric cancer stem cells, the gastric tissue quality was significantly higher than that in normal nude mice of gastric cancer (P < 0.05). These findings indicate that gastric cancer stem cells responsible for tumor invasion and migration have stronger angiogenesis ability. 相似文献
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目的评价大黄灌肠联合前列地尔在重症急性胰腺炎(SAP)中的作用,探求治疗SAP有效、安全、经济的方法。方法将120例SAP患者随机分为3组,对照1组40例予常规治疗,对照2组40例予常规加前列地尔治疗。治疗组40例予常规加前列地尔及大黄灌肠治疗,3组均治疗7 d后,比较治疗前后血浆D-二聚体、C反应蛋白(CRP)、Balthazar CT评分,及治疗后首次自主排便时间、腹痛缓解时间。结果 3组治疗后D-二聚体、CRP水平及Balthazar CT评分、首次自主排便时间及腹痛缓解时间两两比较差异均有统计学意义(P<0.05),且治疗组优于对照1、2组(P<0.05)。结论大黄灌肠联合前列地尔治疗SAP有效、安全,值得推广。 相似文献
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