黄豆苷元胶囊治疗围绝经期综合症疗效观察

目的评价黄豆苷元胶囊治疗围绝经期综合症的有效性。方法60例围绝经期妇女随机分为黄豆苷元组(32例)和对照组(28例),黄豆苷元组口服黄豆苷元胶囊150mg·d-1,对照组口服倍美力片0.625mg·d-1,两组连续治疗3个月。用药前及用药3个月后观察围绝经期征候群,测血清E2,FSH,LH及脂蛋白,并观察药物不良反应。结果两组围绝经期征候群均有显著改善,FSH,LH均显著下降,E2均显著上升,两组比较差异无显著性;两组TC,TG,LDL均有明显下降,HDL略有上升,黄豆苷元组变化略大于对照组,但差异无显著性。胃肠道反应、阴道出血、乳房肿胀发生率黄豆苷元组分别为:12.5%,0,0,对照组分别为:42.9%,75%,21.4%,两组比较有显著差异。结论黄豆苷元胶囊对围绝经期综合征有显著疗效,而且药物副作用小。     

低频电刺激在宫颈癌根治术后康复的应用

目的 探讨低频电刺激在宫颈癌术后镇痛、胃肠功能恢复、预防尿潴留、预防血栓中的应用。方法 选取2020年5月至2021年10月于盐城市第一人民医院行宫颈癌根治手术的患者52例,采用随机数字表法分为对照组25例(予常规术后护理)和试验组27例(在对照组基础上予以低频电刺激)。对比两组术后镇痛效果[视觉模拟评分法(visual analogue scale, VAS)]、胃肠功能恢复情况、排尿及凝血相关情况,并观察术后尿潴留、血栓发生情况。结果 试验组术后24 h VAS评分[(3.52±1.01)分]、48 h VAS评分[(2.41±0.97)分]均低于对照组[(4.36±0.95)分、(3.2±1.08)分],差异有统计学意义(P<0.05)。术后肠蠕动恢复时间[(34.23±10.38)h]、首次排气时间[(43.69±8.06)h]、首次排便时间[(43.69±8.06)h]均短于对照组[(40.45±11.49)h、(52.32±11.68)h、(69.16±9.6)h],差异有统计学意义(P<0.05),试验组术后纤维蛋白原降解产物[(8.33±3.91)ug/mL...     

宫颈环形电切术与阴道镜下活检在诊断宫颈上皮内瘤样变价值比较

Objective To compare the diagnostic clinical significance between loop electrosurgical excision procedure (LEEP) and colposcopical biopsy for cervical intracpithelial neoplasia(CIN). Methods 130 cases of pa-tients diagnosed as CIN under colposcopical biopsy were treated by LEEP in court of gynecology clinic. The conven-tional pathologic diagnosis was recorded in all conization specimens. Results The coincidence rate between colpo-scopical biopsy and LEEP biopsy in CIN Ⅰ, CIN Ⅱ, CIN Ⅲ (not comprised carcinoma in situ) was 55.26%,66.10% ,78.79% respectively;The total coincidence rate was 66.15%. The accuracy of colposcopic biopsy for diag-nosing CINⅢ was higher than that for CIN Ⅰ and CIN Ⅱ,but there was no statistical difference. Conclusion Colpo-scopical biopsy for cervical lesions can be achieved for the frist time the results of pathology, have limitations. LEEP biopsy can compensate partially the deficiency of colposcopic biopsy. In a dear diagnosis of CIN, LEEP biopsy and colposcopical biopsy may complement each other, and achieve thcrpeutic effects.     

宫颈环形电切术与阴道镜下活检在诊断宫颈上皮内瘤样变价值比较

Objective To compare the diagnostic clinical significance between loop electrosurgical excision procedure (LEEP) and colposcopical biopsy for cervical intracpithelial neoplasia(CIN). Methods 130 cases of pa-tients diagnosed as CIN under colposcopical biopsy were treated by LEEP in court of gynecology clinic. The conven-tional pathologic diagnosis was recorded in all conization specimens. Results The coincidence rate between colpo-scopical biopsy and LEEP biopsy in CIN Ⅰ, CIN Ⅱ, CIN Ⅲ (not comprised carcinoma in situ) was 55.26%,66.10% ,78.79% respectively;The total coincidence rate was 66.15%. The accuracy of colposcopic biopsy for diag-nosing CINⅢ was higher than that for CIN Ⅰ and CIN Ⅱ,but there was no statistical difference. Conclusion Colpo-scopical biopsy for cervical lesions can be achieved for the frist time the results of pathology, have limitations. LEEP biopsy can compensate partially the deficiency of colposcopic biopsy. In a dear diagnosis of CIN, LEEP biopsy and colposcopical biopsy may complement each other, and achieve thcrpeutic effects.     

宫颈环形电切术与阴道镜下活检在诊断宫颈上皮内瘤样变价值比较

Objective To compare the diagnostic clinical significance between loop electrosurgical excision procedure (LEEP) and colposcopical biopsy for cervical intracpithelial neoplasia(CIN). Methods 130 cases of pa-tients diagnosed as CIN under colposcopical biopsy were treated by LEEP in court of gynecology clinic. The conven-tional pathologic diagnosis was recorded in all conization specimens. Results The coincidence rate between colpo-scopical biopsy and LEEP biopsy in CIN Ⅰ, CIN Ⅱ, CIN Ⅲ (not comprised carcinoma in situ) was 55.26%,66.10% ,78.79% respectively;The total coincidence rate was 66.15%. The accuracy of colposcopic biopsy for diag-nosing CINⅢ was higher than that for CIN Ⅰ and CIN Ⅱ,but there was no statistical difference. Conclusion Colpo-scopical biopsy for cervical lesions can be achieved for the frist time the results of pathology, have limitations. LEEP biopsy can compensate partially the deficiency of colposcopic biopsy. In a dear diagnosis of CIN, LEEP biopsy and colposcopical biopsy may complement each other, and achieve thcrpeutic effects.     

以持续性枕横位为手术指征的剖宫产86例分析

目的：探讨避免及处理持续性枕横位的方法,以求更好地提高产科质量。方法：以持续性枕横位为手术指征的86例剖宫产为研究对象,对其中可能与持续性枕横位的形成及处理有关的因素、指标等进行回顾性分析及研究。结果：造成持续性枕横位的原因有多个,其中最主要的是宫缩乏力;持续性枕横位的处理纠正也是多方面的,其中最主要的是加强宫缩及体位纠正胎方位,并强调早期处理及时纠正。结论：持续性枕横位通过及时发现、正确处理纠正后,应该是可以避免及减少发生的,且剖宫产并非是其最终唯一的处理手段。当然,严格观察产程是关键。     

子宫肌瘤患者手术治疗后更年期综合征发生情况随访观察

将100例子宫肌瘤患者分为3组,Ⅰ组30例,年龄30～40岁,行次全子宫切除术;Ⅱ组30例,年龄30～40岁,行全子宫切除术;Ⅲ组40例,年龄41～45岁,行全子宫切除术.将40例年龄30～45岁的健康女性作为对照组.对3组手术患者在术后3、6、12、24个月各复查1次雌二醇、卵泡刺激素,并观察患者更年期综合征发生情况.对照组接受同期观察.结果3组手术患者按要求完成术后随访计划的共70例,其中Ⅰ组30例、Ⅱ组20例、Ⅲ组20例.Ⅲ组患者术后24个月雌二醇、卵泡刺激素水平与术前、术后3～12个月比较,P＜0.05.Ⅲ组术后24个月更年期综合征发生情况与Ⅰ、Ⅱ组、对照组同期比较,P＜0.01.认为≤40岁的子宫肌瘤患者接受次全子宫切除术或全子宫切除术后2年内卵巢功能无改变;41～45岁患者术后2年内卵巢功能有改变,且比同年龄段健康女性提前出现更年期综合征(P<0.01).     

孕期高ABO血型抗体效价孕妇的药物干预效果观察

目的探讨夫妇血型不合孕妇产前IgG抗-A(B)抗体效价测定结果,指导临床对高效价孕妇进行药物干预,以防治新生儿溶血病的发生。方法自2010年9月—2012年9月,对来该院妇科进行产前检查的1756例孕妇夫妇进行ABO、Rh血型检测,对夫妇血型不合的孕妇做血型抗体筛选和抗体效价测定,对抗体效价≥1∶512的孕妇(干预组)进行药物干预,产后婴儿做HDN三项试验,与抗体效价≥1∶512未实施药物干预的39例孕妇(对照组)出生的新生儿比较,比较干预前后新生儿溶血病发生情况。结果 1756例孕妇中夫妇ABO血型不合的孕妇有409例,其中IgG抗-A(B)抗体效价≥1∶512的46例,干预组新生儿发生溶血6例(13.04%),对照组新生儿发生溶血29例(74.36%)。结论新生儿溶血病发生率与孕妇IgG抗-A(B)抗体效价呈正相关,对抗体效价高的高危孕妇进行药物干预,可有效降低新生儿溶血病的发生率。     

宫颈环形电切术与阴道镜下活检在诊断宫颈上皮内瘤样变价值比较

Objective To compare the diagnostic clinical significance between loop electrosurgical excision procedure (LEEP) and colposcopical biopsy for cervical intracpithelial neoplasia(CIN). Methods 130 cases of pa-tients diagnosed as CIN under colposcopical biopsy were treated by LEEP in court of gynecology clinic. The conven-tional pathologic diagnosis was recorded in all conization specimens. Results The coincidence rate between colpo-scopical biopsy and LEEP biopsy in CIN Ⅰ, CIN Ⅱ, CIN Ⅲ (not comprised carcinoma in situ) was 55.26%,66.10% ,78.79% respectively;The total coincidence rate was 66.15%. The accuracy of colposcopic biopsy for diag-nosing CINⅢ was higher than that for CIN Ⅰ and CIN Ⅱ,but there was no statistical difference. Conclusion Colpo-scopical biopsy for cervical lesions can be achieved for the frist time the results of pathology, have limitations. LEEP biopsy can compensate partially the deficiency of colposcopic biopsy. In a dear diagnosis of CIN, LEEP biopsy and colposcopical biopsy may complement each other, and achieve thcrpeutic effects.