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沙眼衣原体感染后热休克蛋白对妊娠的影响 总被引:1,自引:0,他引:1
妊娠期间,机体在多种应激原作用下能激活热休克蛋白(HSP)基因转录。其作用:在一定的应激强度范围内,保护胚胎,使胚胎得以存活;另一方面,当应激强度超过一定阈值,HSP则干扰胚胎的生长发育,造成病理妊娠。女性生殖道感染沙眼衣原体(CT)已成为临床常见的疾病之一,可引起一系列并发症,妊娠感染CT还可直接导致妊娠失败,对人类健康构成极大危害。本文对HSP与CT两方面的研究进展进行综述,探讨二者的关系以及对妊娠的影响和作用机制,以期为临床提供预防、诊断和治疗的理论依据。 相似文献
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妊娠期间,机体在多种应激原作用下能激活热休克蛋白(HSP)基因转录.其作用:在一定的应激强度范围内,保护胚胎,使胚胎得以存活;另一方面,当应激强度超过一定阈值,HSP则干扰胚胎的生长发育,造成病理妊娠.女性生殖道感染沙眼衣原体(CT)已成为临床常见的疾病之一,可引起一系列并发症,妊娠感染CT还可直接导致妊娠失败,对人类健康构成极大危害.本文对HSP与CT两方面的研究进展进行综述,探讨二者的关系以及对妊娠的影响和作用机制,以期为临床提供预防、诊断和治疗的理论依据. 相似文献
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目的 观察产前经腹联合经阴道超声检查对前置胎盘并胎盘植入的诊断效能.方法 回顾性分76例前置胎盘并胎盘植入孕妇产前超声资料,其中39例接受单纯经腹超声检查(经腹检查组)、37例接受经腹联合经阴道超声检查(联合检查组);比较2组诊断胎盘植入准确率,分析联合检查组胎盘植入分型准确率.结果 联合检查组产前诊断胎盘植入准确率9... 相似文献
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The study examined the inhibitory effect of Atractylodes macrocephala(AM) on the uterine contraction during premature delivery and explored its electrophysiological mechanism by studying the effects of AM on the Ca2 -activated K currents of pregnant human myometrial smooth muscle cells with or without the treatment with interleukin-6.Single cells were acutely isolated from pregnant human myometrial smooth muscles.Whole-cell Ca2 -activated K currents were recorded by using an Axopatch1-D amplifier.The cells were divided into three groups: group A in which AM was added into perfusate,group B,in which interleukin-6 was added into perfusate) and group C in which AM was added into perfusate after addition of interleukin-6.IL-6 10 ng/mL inhibited BKca by 36.9%±13.7% as compared with control(P<0.01).AM at 2 mg/mL raised BKca by 36.7%±22.6% or 45.2%±13.7% with or without the treatment of IL-6,respectively(P<0.01).It is concluded that AM was able to enhance the BKca of pregnant human myometrial smooth muscle cells treated or un-treated with interleukin-6 and its effect on the BKca IL-treated cells was stronger that its effect on BKca of untreated cells.Our results suggested that AM can help to maintain the membrane potentials and the resting status of pregnant human myometrial smooth muscle cells. 相似文献