THE CAIMA SYSTEM

CAIMA is the abbreviation of Computer-Assisted Instant Monitoring drug Administration. CAIMA works on the principle of closed-loop negative feedback. Special programs have been designed to meet the needs of: a) Patients' safety, b) Response level desired, c) Output necessary for actuating the injecting pump. The pump forces the drug solution to enter the body with high precision. The author shows 8-year experience of using CAIMA system in laboratory and in hospital operating rooms. Experimental studies revealed that: CAIMA system attenuates the overshots and undershots usually present in reaction to drug administration, thus saves the drug and thereby causes less side-efiffeets, while the recovery is also much shortened. CAIMA system provides a greater tolerance to extra-stimuli and preserves the body original reactive sensitivity to drug. The homeostasis in animals is better kept with CAIMA than without. Clinically, the arbitrary hypotension during brain surgery with sodium nitroprusside and the control of muscle relaxation in general surgery with muscle relaxants have been successful using CAIMA system.     

咪唑安定与维库溴铵相互作用的实验研究

通过在体兔坐骨神经－胫前肌标本，研究咪唑安定与维库溴铵之间可能的相互作用。在维库溴铵稳定状态神经肌肉阻滞下，咪唑安定０．３和１．５ｍｇ／ｋｇ分别抑制震颤强度２３．５％和３７％；而咪唑安定１．５ｍｇ／ｋｇ使维库溴铵累积剂量－反应曲线左移，但斜率不变。     

P波触发检测体表希氏束电图

本文报道体表希氏束电图检测的一种新方法。它利用放大、整形为方波的P波,直接触发迭加仪扫描迭加.动物实验证明,在正常情况下和用药物造成人为房室传导阻滞情况下,体表测出的HPS-V间期和心腔内记录的H-V间期有良好的相关性.我们用本检测法对10名正常人测定,测得HPS-V间期范围为28～41毫秒,重复性良好.     

心阻抗图运动试验对冠心病诊断价值的初步探讨

心阻抗图是简便安全并能连续测定心搏出量的非侵入性方法,其临床价值也进一步得到证实。本文报告34例受试者在运动试验前后同时记录心阻抗图及心电图,证实对冠心病确诊有参考价值,对心功能估价亦提供客观依据。     

异氟醚对罗库溴铵肌松效应影响的实验研究

目的　通过在体兔坐骨神经一胫前肌标本的制备,研究异氟醚对单次静注和连续输注罗库溴铵肌松效应的影响。方法　实验家兔均采用异氟醚全麻。10只家兔分为两组观测,观察组间单次静注罗库溴铵的肌松时效的变化;另取10只家兔分为两组,观察组间罗库溴铵连续输注后的肌松时效和输注量的变化。结果　单次静注罗库溴铵(2 倍 ED95 )时,异氟醚使其作用时间延长约 7min(P<0 .05),同时罗库溴铵对血液动力学影响轻微;连续静注罗库溴铵时,异氟醚使罗库溴铵的静脉输注需要量减少40%(P<0 .05),而对起效和恢复指数无明显影响。结论　异氟醚能增强罗库溴铵的肌松时效。