Study on correlation of mammographic features、pathology and molecular bology of breast infiltrating ductal carcinoma

Objective To investigate the correlation among mammographic features、pathology and molecu-lar biology markers of breast infitrating ductal carcinoma(IDC) tissues.Methods The mammographic features of 93 cases with IDC confirmed by surgery and histopathology were analyzed retrospectively.The mastectomy specimens of the IDC were stained with immunohistochemistry,and the expression of ER、PR、C-erbB-2 were measured.The rela-tionship between the immunohistochemical pathologic results and mammographic features was analyzed.Results A-mong the 93 cases of IDC,ER positive expression was positively correlated with the spiculate margin of breast cancer (P<0.05);C-erbB-2 positive expression was positively correlated(P<0.05).Moreover,ER and PR positive expres-sion showed a significant inverse correlation with the calcifying of breast cancer(P>0.05);ER and PR positive ex-pression was positively correlated with the transfer of lymph(P<0.05);there existed correlation between the positive expression of C-erbB-2 and lymphatic metastasis and pathohistology grade(P<0.05).Conclusion There was a pos-itive correlation among IDC mammography、pathology and the abnormal value of ER、PR and C-erbB-2.The X-ray mammography could reflect the diagnosis value of ER、PR and C-erbB-2 roughly,and thadpractical value in determi-ning prognoses and endocrinotherapy.     

床边消化道造影与床边多普勒超声在危重儿先天性肠旋转不良中的应用

目的:探讨床边消化道造影与床边多普勒超声在危重儿先天性肠旋转不良中的应用。方法:选取我院2017年1月-2019年11月收治的临床高度怀疑先天性肠旋转不良危重儿22例,其中16例患者经手术确诊为先天性肠旋转不良,6例造影检查考虑正常,临床观察治疗后确认为阴性。所有患者在手术前及临床治疗前均接受床边多普勒超声与床边上消化道造影检查,对比床边多普勒超声与床边消化道造影的临床诊断效果。结果:床边消化道造影的准确性为93.75%,较床边多普勒超声68.75%高(P>0.05);床边消化道造影敏感性度为93.75%,较床边多普勒超声68.75%高(P>0.05)。结论:对于患有先天性肠旋转不良疾病的危重儿而言,接受床边多普勒超声与床边消化道造影检查,两种诊断方式各有其优缺点,相对而言,床边消化道造影检查准确率更高,诊断价值更具有临床意义。     

乳腺浸润性导管癌X线表现、病理与分子生物学标记关系的研究

目的 探讨乳腺浸润性导管癌（IDC）X线表现、病理与分子生物学标记之间的关系.方法 分析93例经乳腺X线检查、手术及病理证实的IDC患者的X线表现,术后标本应用免疫组化染色测定癌细胞雌激素受体（ER）、孕激素受体（PR）、癌基因（C-erbB-2）的表达情况,并分析与X线表现之间的关系.结果 93例IDC中,癌肿毛刺状边缘与癌细胞ER阳性表达之间呈正相关（P〈0.05）;癌肿钙化与C-erbB-2阳性表达之间呈正相关（P〈0.05）,而与癌细胞ER和PR阳性表达水平之间呈负相关（P〉0.05）;淋巴结转移与癌细胞ER和PR阳性表达之间呈正相关（P〈0.05）,C-erbB-2阳性表达率与有无淋巴结转移及病理组织学分级有关（P〈0.05）.结论 IDC的X线表现、病理与癌细胞ER、PR、C-erbB-2异常表达有一定的相关性,X线表现可以粗略推测ER、PR及C-erbB-2表达情况,对预测IDC淋巴结转移及判断预后有重要意义.     

儿童中枢性尿崩症影像表现与临床相关性探讨

目的：分析儿童中枢性尿崩症的脑部影像表现,并探讨临床相关性。方法：复习36例儿童中枢性尿崩症的临床资料,对其CT或（和）MR／检查的脑部影像表现及临床进行回顾性分析。结果：生殖细胞瘤6例。颅咽管瘤5例,下丘脑胶质瘤2例,垂体腺瘤2例,郎罕氏细胞组织增生症5例;28例行MRI检查病例中,除了2例具有正常垂体后叶T1加权像高信号外,26例垂体后叶T1加权像高信号均消失,其中垂体小、发育不良8例,垂体柄异常16例。结论：儿童中枢性尿崩症中继发性尿崩症比例较高,且病因各异,因此对临床确诊的儿童中枢性尿崩症非常有必要做CT或（和）MRI检查。     

Study on correlation of mammographic features、pathology and molecular bology of breast infiltrating ductal carcinoma

Objective To investigate the correlation among mammographic features、pathology and molecu-lar biology markers of breast infitrating ductal carcinoma(IDC) tissues.Methods The mammographic features of 93 cases with IDC confirmed by surgery and histopathology were analyzed retrospectively.The mastectomy specimens of the IDC were stained with immunohistochemistry,and the expression of ER、PR、C-erbB-2 were measured.The rela-tionship between the immunohistochemical pathologic results and mammographic features was analyzed.Results A-mong the 93 cases of IDC,ER positive expression was positively correlated with the spiculate margin of breast cancer (P<0.05);C-erbB-2 positive expression was positively correlated(P<0.05).Moreover,ER and PR positive expres-sion showed a significant inverse correlation with the calcifying of breast cancer(P>0.05);ER and PR positive ex-pression was positively correlated with the transfer of lymph(P<0.05);there existed correlation between the positive expression of C-erbB-2 and lymphatic metastasis and pathohistology grade(P<0.05).Conclusion There was a pos-itive correlation among IDC mammography、pathology and the abnormal value of ER、PR and C-erbB-2.The X-ray mammography could reflect the diagnosis value of ER、PR and C-erbB-2 roughly,and thadpractical value in determi-ning prognoses and endocrinotherapy.     

螺旋CT尿路造影对小儿泌尿系畸形的诊断价值

目的探讨螺旋CT尿路造影（CTU）对小儿泌尿系畸形的临床诊断价值。方法对45例小儿泌尿系畸形的患儿行CT平扫和肾实质期及排泄期扫描,将原始图像传送至工作站进行后处理,获得MPR、MIP、CPR和VR图像。结果经CTU诊断泌尿系畸形45例,包括单侧肾盂与输尿管重复畸形14例,双侧肾盂与输尿管重复畸形2例,肾盂与输尿管交界部梗阻9例,异位肾2例,先天性肾发育不良5例,多囊性发育不良肾1例,融合肾5例,孤立肾2例,肾旋转不良2例,巨输尿管1例,腔静脉后输尿管1例,膀胱憩室1例。结论 CTU具有扫描速度快,覆盖范围广,薄层扫描能力,多角度三维成像等优点,对小儿泌尿系畸形的诊断具有重要价值。