Analysis of Therapeutic Effect of X-knife on Intracranial Tumors in 44 Cases

By linear electron accelerator KD II of Siemens M evatron and RSA X－knife of the fourth generation produced by Radionics company, 44 patient with intracranial diseases were intervened through 1999,6－2000,4. The results are as following.1 Materials and Methods1.1 Mateials In the group,25 male,19 female aging from 8～74 years, meanly 43 years.Total 50 lesions were radiated.Of all the patients, 12 patients with metastatic tumors of brain (7 with solitary tumors,5 with multiple tumors);3 w…     

X-刀治疗颅内疾病44例疗效分析

Objective to investigate therapeutic methods and effect of X-knife for on intracranial diseases. Method Recent effect of 44pqtients with cranial diseases by X-knife was observed. Radiological follow-up was performed on 40 cases with mean 5.65 months of followup time. Result 92.5% of tumors were controlled locally, stability and recovery rate was 90.0%. The local control of metastatic tumors of brain was higher, but most patients with metastatic tumors died of primary lesion. New metastatic lesions appeared in patients without panencephalic radiotherapy in 1～5months. Tumors of pineal region were sensitive to X-knife. Conclusion X-knife has a definite effect on intracranial diseases. For patients with tumors of pineal region complicated by serious hydrocephalus, shunting should be conducted before X-knife treatment. For patients with mild or morderate hydrocephalus, X-knife chould be utilized only under correct interventions such as dehydration. The local control rate of intracranial metastatic tumors was high, but survival time postoperation depended on panencephalic radiotherapy or control of primafry lision. For tumors with diameter＞ 3cm, pituitary tumors, brains stem tumors and tumors in cerebellopontine angle region repeated X-knife were suggested, which could improve cure rate and decrease complications.     

X—刀治疗颅内疾病44例疗效分析

1999年 6月～ 2 0 0 0年 4月 ,我院以ＳｉｅｍｅｎｓＭｅ ｖａｔｒｏｎＫＤ 2型电子直线加速器 ,美国Ｒａｄｉｏｎｉｃｓ公司产ＲＳＡ第四代Ｘ 刀系统 ,共完成 4 4例颅脑疾病的Ｘ 刀治疗 ,现将结果报告如下 :临床资料一般资料 :本组 4 4例 ,男 2 5例 ,女 19例。年龄8～ 74岁 ,平均 4 3岁。共照射 50个病灶。脑转移瘤12例 (单发 7例 ,多发 5例 ) ;听神经瘤 3例 ;胶质瘤14例 ;脑膜瘤 4例 ;松果体区肿瘤 5例 ;海绵状血管瘤 1例 ;ＡＶＭ 1例 ;室管膜瘤 1例 ;垂体瘤 3例。以上病例全部根据病史、ＣＴ、ＭＲＩ或全脑血管造影(ＤＳＡ)诊断 ,其中开…