腱鞘巨细胞瘤研究进展

腱鞘巨细胞瘤（GCTTS）是一类起源于关节、滑囊和腱鞘滑膜的增生性炎症性疾病,根据其生长方式分为局限型和弥漫型,通常表现为独立、无痛、生长缓慢的肿块。GCTTS首选治疗方法是手术切除,术后有较高的复发率。目前对GCTTS病因、治疗及术后复发危险因素仍存在争议。该文就GCTTS研究进展进行综述。     

LARS韧带治疗跟腱闭合断裂伤短期疗效观察

<正>我院2008年10月至2009年3月共收治跟腱断裂(闭合损伤)患者12例,全部行手术治疗,其中10例常规跟腱Kessler缝合,跖肌腱或腓肠肌腱膜瓣修补,2例使用LARS韧带修补,所有病例术后随访3~6个月,现将结果报告如下。1资料与方法1.1一般资料:本组12例,男性11例,女性1例;年龄10~     

FOLFOX-6与肝动脉灌注化疗对结直肠癌肝转移治疗效果的比较

Objective To compare the efficacy and side effects between systemic chemotherapy and hepatic arterial infusion by combination of oxaliplatin and 5-fluorouracil (FOLFOX-6) with 5-fluorouracil in the patients who have developed hepatic metastasis after colorectal cancer operation. The factors that would affect the prognosis without operational treatment were also analyzed. Methods 46patients who had signed the informed consents were allocated into two groups: the group with general chemotherapy (Trial Group includes 26 cases) and the one with hepatic arterial infusion chemotherapy (Control Group includes 20 cases). The total effective rate, the prognosis, the cytoxicitic side effects,quality of life, the total survival rate and the responses were the main parameters determined. Kaplan-Meier was used to analyze Mono-factor to the prognostic responses and the Cox mode was used to analyze poly-factor to the prognostic responses. Results The overall survival rate was significantly higher by using systemic treatment versus HAI(median, 15. 0 v 11.2 months;P＜0.05). The difference in overall responsive rate (CR+PR) between the two groups was statistically significant (50% v 10%;P=0. 011). No significant difference was found in PS scale during the treatment. (P=0. 126). Except for myelosuppression and abdominal pain, no significant difference was found in the other side effects. Univariate analysis revealed that the invasive lesions to serosa, the distribution of liver metastases, the size and number of liver metastases, primary carcinoma involving lymph nodes and the treatment were correlated with prognoses. Cox regression analysis showed that the larger diameter of liver metastases, the number of liver lesions, primary carcinomas involved in serosal layer and the treatment modules were independent prognostic factors. Conclusions The oxaliplatin-based FOLFOX-6 chemotherapy regiment has a better responsive rate and survival rate than the traditional infusion with 5-fluorouracil to the main hepatic artery for interventional therapy. The diameter of the hepatic metastasis larger than 5em, multiple hepatic metastasis and the primary lesions penetrating serosal layer suggest the poor prognosis. The oxaliplatin-based systematic chemotherapy has a better prognosis. Therefore,it is worth carrying on further study on modification of traditional hepatic arterial infusion and on evaluation of therapy by combination of the hepatic arterial infusion with the systematic chemotherapy.     

带血管皮瓣移植综合治疗下肢骨外露

下肢骨外露、慢性骨髓炎患者临床多见,治疗上比较复杂.1997年～2002年采用带血管皮瓣移植的综合方法治疗47例,除2例皮瓣坏死外,其余均一期愈合,成功率94.74%.经回顾性随访和分析,认为带血管皮瓣移植综合治疗下肢骨外露、骨髓炎具有较好疗效,不但可一期覆盖创面,还可以治疗骨、肌腱、神经等主要组织外露的感染创面,是保全肢体、恢复功能的有效方法.     

中重度前臂缺血性肌肉挛缩晚期功能重建的手术治疗

目的 探讨中、重度前臂缺血性肌肉挛缩晚期功能重建的手术方法及疗效。方法 对42例中、重度前臂缺血性肌肉挛缩的晚期患者，进行旋前畸形矫正和旋后对掌功能重建手术。其中6例行指浅、深屈肌腱交叉延长术，17例行肌腱转位术＋骨间膜、旋前方肌松解术，19例行肌腱转位术＋骨间膜、旋前方肌松解术＋腕屈肌旋后功能重建术。结果 术后42例患者均获得6～34个月的随访。旋后功能恢复：优9例，良18例，可12例，差3例，优良率为64．3％。手功能恢复：优11例，良15例，可14例，差2例，优良率为61．9％。结论 对中、重度晚期缺血性肌肉挛缩的患者，应针对其不同的挛缩程度采用不同的手术方法进行治疗。     

周围神经内囊肿的研究进展

周围神经内囊肿是一种良性的、非肿瘤性质的黏液囊肿[1],生长于周围神经外膜内,由厚厚的黏液积聚而成,包裹在致密的纤维囊内。法国解剖学家和外科医生Beauchene fils于1810年首次描述了一位肘部尺神经内囊肿的病人,他称之为“肘部浆液囊肿”[2]。周围神经内囊肿可以发生在全身各处,如颈、肩、肘、腕、髋、膝、踝,直至掌指处[3-4],最常见于膝关节,约占68%,主要累及腓总神经,其次为肘关节,约占10%,主要累及尺神经[5]。     

Volkmann肌挛缩的治疗

本院１９８８～１９９９年共收治前臂缺血肌挛缩（Ｖｏｌｋｍａｎｎ肌挛缩）６７例。经回顾性随访和分析，我们认为采用旋前方肌、骨间膜松解加克氏针固定，配合系列康复训练能有效防止族前畸形复发。１资料与方法１．１资料本组前臂缺血肌挛缩病人共６７例。年龄２～５６岁，平均１６．５６岁，男５６例，女 １１例。致伤原因：石膏固定 １３例，夹板固定２５例，术后形成１６例，其他１３例。伴有族前畸形３８例，旋前畸形处理：失去手术时机未处理１１例，松解＋石膏外固定１５例，松解＋克氏针固定１１例，骨折端调整１例。１．２方法本…     

腹腔镜下直肠癌扩大根治手术5例报告

腹腔镜下直肠癌手术是目前腹腔镜消化道手术中较成熟的一种手术方式，但腹腔镜下直肠癌淋巴结清扫难度大。我院2006年1～6月施行5例腹腔镜下直肠癌切除扩大淋巴结清扫（其中1例为后盆腔切除加淋巴结清扫术），现报道如下。     

尺偏型肱骨髁上骨折肘内翻并发症的手术干涉

<正>肱骨髁上骨折(supracondylar fracture of humerus,SFH)并发肘内翻畸形长期以来一直是骨科医师面临的专业难题,国内外学者进行了大量研究[1-3],但其发病率一直居高不下,国内报道为3.3%~79.2%[4,5],平均达30%[6]。现将我科相关治疗报告如下。1资料与方法1.1一般资料:2005—2007年共手术治疗5~10岁组儿童尺