全文获取类型
收费全文 | 2468篇 |
免费 | 111篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 26篇 |
儿科学 | 48篇 |
妇产科学 | 12篇 |
基础医学 | 369篇 |
口腔科学 | 74篇 |
临床医学 | 140篇 |
内科学 | 606篇 |
皮肤病学 | 71篇 |
神经病学 | 214篇 |
特种医学 | 79篇 |
外科学 | 338篇 |
综合类 | 3篇 |
预防医学 | 67篇 |
眼科学 | 111篇 |
药学 | 191篇 |
中国医学 | 15篇 |
肿瘤学 | 224篇 |
出版年
2023年 | 14篇 |
2022年 | 38篇 |
2021年 | 72篇 |
2020年 | 39篇 |
2019年 | 35篇 |
2018年 | 44篇 |
2017年 | 44篇 |
2016年 | 44篇 |
2015年 | 42篇 |
2014年 | 57篇 |
2013年 | 58篇 |
2012年 | 124篇 |
2011年 | 153篇 |
2010年 | 86篇 |
2009年 | 84篇 |
2008年 | 147篇 |
2007年 | 156篇 |
2006年 | 142篇 |
2005年 | 136篇 |
2004年 | 150篇 |
2003年 | 120篇 |
2002年 | 136篇 |
2001年 | 42篇 |
2000年 | 49篇 |
1999年 | 43篇 |
1998年 | 25篇 |
1997年 | 16篇 |
1996年 | 17篇 |
1995年 | 15篇 |
1994年 | 23篇 |
1993年 | 18篇 |
1992年 | 37篇 |
1991年 | 51篇 |
1990年 | 51篇 |
1989年 | 44篇 |
1988年 | 37篇 |
1987年 | 28篇 |
1986年 | 24篇 |
1985年 | 27篇 |
1984年 | 19篇 |
1983年 | 12篇 |
1982年 | 16篇 |
1981年 | 8篇 |
1979年 | 8篇 |
1978年 | 5篇 |
1975年 | 4篇 |
1974年 | 9篇 |
1973年 | 7篇 |
1972年 | 6篇 |
1967年 | 6篇 |
排序方式: 共有2588条查询结果,搜索用时 15 毫秒
1.
Yoichiro Hosokawa D.D.S. D.D.Sc. Kazuyuki Minowa D.D.S. Satoru Abe M.D. Keiichi Ohmori D.D.S. D.D.Sc. Michio Yamasaki M.D. D.M.Sc. Masanobu Shindoh D.D.S. D.D.Sc. Tadashi Iizuka D.D.S. D.D.Sc. Mohiuddin Ahmed B.D.S. Akira Amemiya D.D.S. D.D.Sc. 《Oral Radiology》1991,7(1):1-6
A case of an odontogenic tumor which invaded the intracranial space from the mandible is reported. Judging from the radiographic
images it was similar to a malignant tumor. The patient died 17 years after the first visit. According to the final pathological
diagnosis, it was malignant odontogenic mixed tumor of low grade which did not belong to any of the WHO classification. 相似文献
2.
K Kondoh S Sasaki T Oku S Minohara S Hasegawa Y Sawada M Morita A Takeuchi 《Kyobu geka. The Japanese journal of thoracic surgery》1992,45(7):565-9; discussion 569-72
In six hundred and six consecutive patients undergoing coronary artery bypass grafting (CABG) within the past 17 years (May 1974 to March 1991), repeated CABG were performed on 10 patients (1.65%). The main reasons for repeated CABG were graft failure (GF) in 8, progression of native disease (NP) in 5 and incomplete revascularization (IR) in 3 patients. The incidence of GF was high either within a half year or around 5 years after CABG. Although all patients survived from reoperation, four patients continued to have mild angina pectoris. When the recurrence of angina is noted after CABG, coronary arteriography and if necessary PTCA should be done as soon as possible. If a second surgery is inevitable, maximum utilization of arterial graft and accomplishment of complete revascularization are emphasized. 相似文献
3.
Yasuhiro Yamaoka Takatomo Mine Hiroshi Tanaka Yoichiro Ishida Tosihiko Taguchi 《Knee surgery, sports traumatology, arthroscopy》2007,15(11):1346-1349
An avulsion fracture of the tibial tubercle is a common injury in traffic accident. If the fracture is closed, then a comparatively
good prognosis can be expected through reinforcement of the bone via osteosynthesis and the use of artificial ligaments. In
this case, an open wound was observed in the tibial tubercle, and the wound was so polluted that the healing process was significantly
delayed. It was therefore difficult to provide simultaneous surgical treatment and so three operations were required to perform
the reconstruction of the extensor mechanism. The reconstruction of extensor mechanism and the frame fixation between the
patella and tibia was performed. Six months after the injury, the patient was able to walk without aid, had a range of movement
from 5°to 130°, and did not show any indications of ADL disorder. Using this method of frame fixation between the patella
and tibia proved to be an effective technique for the reconstruction of the open knee extension mechanism injury. 相似文献
4.
Sadahisa Okamoto Yuichiro Inatomi Toshiro Yonehara Yoichiro Hashimoto Teruyuki Hirano Makoto Uchino 《Clinical neurology》2006,46(5):307-311
In order to determine predictive factors of early seizures (ES) after acute stroke and to estimate prognosis, we retrospectively examined clinical data of 1,743 consecutive patients with acute ischemic stroke. The subjects were divided into two groups; an ES group (19 patients) and a non-ES group (1,724 patients). Multivariate statistical analysis revealed that the NIH-Stroke Scale score on admission (/10, OR, 1.1: 95% CI 1.04 to 1.13) and positive past history of cerebrovascular disease or brain injury (OR, 3.85: 95% CI 1.49 to 9.95) are significant factors to predict ES. There was no significant difference in the outcome between the two groups. A recurrence of seizures, after follow up for 4 to 40 months, was observed only in one patient with a history of ES. 相似文献
5.
Yasuyuki Ito Akira Mori Kiminobu Yonemura Yoichiro Hashimoto Teruyuki Hirano Makoto Uchino 《Clinical neurology》2007,47(9):589-592
We presented here two patients with hemorrhagic infarction occurred during subacute phase of brain embolism. The patients were 71-year-old and 73-year-old men who suffered from brain infarction of the left posterior cerebral artery and right middle cerebral artery territory, respectively. Both of them were diagnosed as having cryptogenic stroke and patent foramen ovale. After transferred to rehabilitation hospitals taking aspirin for a secondary prevention of stroke, they developed hemorrhagic infarction at day 17 and day 19, respectively. Their blood pressure remained within normal range throughout acute and subacute phase. Although most of hemorrhagic infarction occurs within 24 hours of stroke onset, some patients develop symptomatic hemorrhagic infarction even after 10 days. We need to be careful about late-onset hemorrhagic infarction, because many patients are now transferred early to rehabilitation hospitals to facilitate dedicated systematic rehabilitation. 相似文献
6.
Wakana Goto Hidehiro Oku Takashi Okuno Tetsuya Sugiyama Tsunehiko Ikeda 《Journal of ocular pharmacology and therapeutics》2003,19(1):63-73
We investigated whether topical instillation of an alpha(1)-adrenergic blocker would improve an insufficient blood supply in the optic nerve head (ONH) and visual function, in rabbits. The effect of systemic NOS inhibition on visual-evoked potentials (VEPs) and hemodynamics in ONH were determined. VEPs were recorded before and every 15 min during a 120-min observation period after an intravenous injection of 50 mg/kg N(G)-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase (NOS) inhibitor. Capillary blood flow in ONH was evaluated by the laser speckle method throughout the same period. Then, we investigated the effect of topical instillation of a recently developed alpha(1) adrenergic blocker, bunazosin hydrochloride (0.01%), 60 min prior to the intravenous L-NAME (50 mg/kg) on the changes by NOS inhibition. The VEP amplitudes were reduced by L-NAME (10, 20, and 50 mg/kg) in a dose-dependent manner, while the VEP implicit time was unchanged, and no significant changes were detected in the electroretinogram. The reductions in ONH capillary blood flow and VEP amplitudes caused by L-NAME (50 mg/kg) were significantly suppressed by an instillation of bunazosin hydrochloride. These results indicate that blocking alpha(1)-adrenergic receptors may ameliorate the impairments in blood flow and retinal function caused by NOS inhibition. The enhancement of basal vascular tone due to deprivation of continuous NO production may be diminished by this alpha(1)-adrenergic blocker. 相似文献
7.
8.
Lipid peroxidation in transplanted rat liver 总被引:2,自引:0,他引:2
9.
10.
Intraperitoneal high-dose cisplatinum chemotherapy (CDDP-ip) in patients with carcinomatous peritonitis 总被引:1,自引:0,他引:1
T Noda M Oku Y Kiyozuka Y Ninomiya K Hino Y Okamura M Maruyama M Ichijo 《Gan to kagaku ryoho. Cancer & chemotherapy》1987,14(4):1025-1032
Immediately after CDDP-ip, the level of free Pt in ascites reached nearly 100 micrograms/ml, and the AUC (area under the curve) for ascites was 20-140 times greater than that for serum. The free Pt in serum following CDDP-ip administration was detected for several hours, and interestingly, the AUC for serum after ip therapy was 0.4-2.2 times greater than that after iv therapy. As a result, free Pt was found to act on cancer cells in the abdominal cavity directly at a high concentration. At the same time, the possibility of an antitumor effect from the vascular side of the tumor was also suggested. On the other hand, cases of ovarian cancer had various levels of peritoneal clearance (CLp), which depended on the severity of their carcinomatous peritonitis. The CLp had a great influence on the peak plasma concentration and on the AUC of free Pt in serum. In particular, the peak plasma concentration produced by CDDP-ip was 40-80% of the plasma concentration produced by CDDP-iv. These findings indicate that high-dose CDDP-ip is possibly effective and useful for advanced ovarian cancer, producing only very mild side effects. 相似文献