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Sampatti Sambhaji Todkar Venktesh V Gujarathi Vinay S Tapare 《Indian Journal of Community Medicine》2009,34(3):183-187
Background:
Hypertension is most common cardiovascular disease and it account for large proportion of all cardiovascular deaths and disability worldwide.Research Questions:
What is the level of prevalence of hypertension in rural area? What are the soociodemographic factors associated with hypertension?Objectives:
To find out prevalence of hypertension in rural area.Study Design:
A community-based cross-sectional study setting: Rural Health Training Centre Paithan, field practice area of govt. medical college Aurangabad, Maharashtra.Participants:
1297 persons aged 19 years and above.Study Period:
June 2005 to December 2006.Materials and Methods:
A house-to-house survey was conducted by the author himself, interviewed the participants by systematic random sampling method, using pretested structured standard questionnaire. Two independent blood pressure (BP) readings were taken in sitting position by visiting each participant at their home. Hypertension was defined as systolic BP more than or equal to 140 mm of Hg or diastolic BP more than or equal to 90 mm of Hg or those individuals currently taking antihypertensive treatment.Statistical Tests:
Percentiles, Chi Square test, Chi-Square for linear trend, multiple logistic regression analysis on SPSS software Version 10.Results:
Overall prevalence of hypertension in the study subjects was 7.24%. Multiple logistic regression analysis identified various factors significantly associated with hypertension were age, sex, BMI, additional salt intake, smoking, DM, alcohol consumption, and higher socioeconomic status.Conclusions:
The overall prevalence of hypertension in study subjects was 7.24%. 相似文献5.
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Pardi DS Ramnath VR Loftus EV Tremaine WJ Sandborn WJ 《The American journal of gastroenterology》2002,97(11):2829-2833
OBJECTIVE: There are no reports of the clinical features or treatment outcomes in large series of patients with lymphocytic colitis, and it is not known whether treatments that appear to be beneficial in patients with collagenous colitis are also beneficial in lymphocytic colitis. We sought to analyze these issues in our patients with lymphocytic colitis. METHODS: All patients with biopsy-proven lymphocytic colitis evaluated at our institution between January 1, 1997, and December 31, 1999, were identified. Clinical features on presentation and treatment outcomes were abstracted from the medical records. RESULTS: A total of 170 patients with lymphocytic colitis were identified (median age 67 yr, 61% female). Diarrhea, bloating, rectal urgency, fecal incontinence, weight loss, concomitant autoimmune disorders, and aspirin or nonsteroidal anti-inflammatory drug use were common. Loperamide, diphenoxylate/atropine, and bismuth subsalicylate were effective therapies and were well tolerated. However, no therapy produced a complete response in more than 40% of patients. CONCLUSIONS: Lymphocytic colitis typically presents in elderly patients as chronic diarrhea. Nocturnal stools, urgency, and abdominal pain occur frequently, as do weight loss, fecal incontinence, and concomitant autoimmune disorders. Many empiric treatment options are used, but overall response rates are disappointing. Randomized controlled trials are needed to determine the optimum therapeutic approach to these patients. 相似文献
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Bartels I; Schlosser M; Bartz UG; Pauer HU 《Human reproduction (Oxford, England)》1998,13(12):3345-3346
One important aspect in the debate on the genetic risks associated with
intracytoplasmic sperm injection (ICSI) is the possible increased rate of
chromosomal abnormalities in resulting pregnancies. ICSI was performed in a
27 year old man with asthenoteratozoospermia and his 25 year old wife.
There was a spontaneous miscarriage at 9 weeks of gestation. Cytogenetic
investigation revealed trisomy 21. Analysis of two polymorphic
microsatellite markers showed that the additional chromosome was paternal.
This is in contrast to the fact that the vast majority of trisomic concepti
are maternal in origin. Identifying the parent of origin in trisomic
conceptions achieved by ICSI may reveal whether ICSI is associated with an
increased risk of paternally derived aneuploidy.
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Pregnancy outcome and anti-Ro/SSA in autoimmune diseases: a retrospective cohort study 总被引:1,自引:0,他引:1
Mavragani CP; Dafni UG; Tzioufas AG; Moutsopoulos HM 《Rheumatology (Oxford, England)》1998,37(7):740-745
OBJECTIVE: In the present retrospective cohort study, the association of
anti-Ro/SSA antibody with pregnancy loss and adverse pregnancy outcome in
women with autoimmune diseases was investigated. MATERIALS AND METHODS:
Obstetric histories of 154 anti-Ro/SSA-positive women with autoimmune
diseases [78 systemic lupus erythematosus (SLE) and 76 non- SLE] were
analysed and compared to a control group of 142 anti-Ro/SSA- negative women
(71 SLE and 71 non-SLE) matched for disease diagnosis and age at the time
of anti-Ro/SSA diagnosis. Obstetric history was also obtained and analysed
from a group of healthy women, frequency matched to anti-Ro/SSA-positive
women on age at study entry. RESULTS: The rate of pregnancy loss and
adverse pregnancy outcome did not differ significantly between
anti-Ro/SSA-positive women, anti-Ro/SSA-negative women and healthy
controls. Anti-Ro/SSA-positive SLE women reported a significantly higher
rate (18.0%) of therapeutic abortions compared to anti-Ro/SSA-negative
women (5.6%, P=0.0244) and healthy controls (4.6%, P=0.0013). Anti-Ro/SSA
non-SLE-positive women reported a significantly higher rate (23.7%) of
recurrent pregnancy loss in comparison to anti- Ro/SSA-negative women
(7.04%, P=0.0063) and healthy controls (6.4%, P=0.0004). CONCLUSIONS:
Although anti-Ro/SSA antibody does not adversely affect pregnancy outcome
in SLE patients, it appears to be associated with recurrent pregnancy loss
in non-SLE patients.
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