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D Mabin J P Borsotti S Tea J C Le Mevel J Clavier 《Revue d'électroencéphalographie et de neurophysiologie clinique》1986,15(4):341-348
Eleven patients with bronchial epidermoid carcinoma and undergoing treatment with cis-D.D.P. (II) were kept under electrophysiological and clinical surveillance. No other neurotoxic medication was added. The total dose of cis-D.D.P. was 300 mg/m2 over a period of three months: namely, three courses of 100 mg/m2 distributed over 5 days. Following the pretreatment check-up, the patients were divided into two groups: those without any electrophysiological abnormality (group A), and those without clinical abnormality but with a delayed latency H of the Hoffmann Reflex (group B). Patients in group A showed a slowing down of the motor nerve conduction velocity of the Median and Peroneal Nerves after a course of 100 mg, without accompanying worsening of the conduction velocity after 300 mg/m2, and prolongation of the distal latency of the sensory Median Nerve after 300 mg/m2; in group B, no significant change of electrophysiological clinical features were noted. In the two groups a non-significant reduction in amplitude of evoked responses were noted. These findings are more consistent with an axonal injury than with functional myelin injury. The authors review the existing literature and discuss the physiopathologic mechanisms of cis-D.D.P. peripheral neuropathies. 相似文献
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Tea Kalebic Jeannette E. Williams James E. Talmadge Chien-Song Kao-Shan Betsy Kravitz Kimberly Locklear Gene P. Siegal Lance A. Liotta Mark E. Sobel Patricia S. Steeg 《Clinical & experimental metastasis》1988,6(4):301-318
Tumor cell invasion of basement membranes is required at several steps in the process of metastasis. To study the genetic and biochemical events mediating invasion, a variant cell line (TK) was selected from the metastatic M2 K1735 murine melanoma cell line. A novel selection procedure was used, based onin vitro andin vivo invasion and growth upon basement membrane and stroma. Additionally, two extrapulmonary metastases of the TK cell line, TK-Eve and TK-Liver, were established as cell lines and characterized. The TK cell line demonstrates greater metastatic potentialin vivo and invasive abilityin vitro than the parent M2 cell line, confirming the validity of the selection procedure. In addition, the M2 and TK cell lines were examined for other cell functions involved in the metastatic process. Cellular growth rates and sensitivity to T lymphocyte and natural killer cell lysis were not determining factors in the metastatic potentials of the M2 and selected cell lines; possible macrophage contribution to metastatic behavior was noted. [35S]methionine pulse labeling of protein synthesis and karyotypic analysis confirm the close relationship of parental and selected cell lines.Supported by contract NDI-23910.Supported by ACS Institution Grant IN-15-Y and NIH Grant MRC-5T34-GM08037.Was a fellow of the Jane Coffin Childs Memorial Fund for Medical Research. This investigation has been aided by a grant from the Jane Coffin Childs Memorial Fund for Medical Research. Also supported by NIH Postdoctoral Fellowship #HD06423. 相似文献
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玉蟾抗衰茶以川绿茶为基质,加入中药配方,精工制作而成,使茶叶的保健治疗作用增强,并具有益气补血,健脾固肾功用。动物实验证实:饮用该茶安全,有增强体力、抗疲劳与抗缺氧能力,能延长动物(家蚕)生命周期。经临床验证本品有降低人体血脂、增强精力、清爽神智等功能,为中老年理想的保健饮料。 相似文献
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Paula Francekovi Lucía García-Torralba Eleni Sakoulogeorga Tea Vu
kovi Federico J. A. Perez-Cueto 《Nutrients》2021,13(4)
The meat production industry is one of the leading contributors of greenhouse gas emissions. Cultured meat presents itself as a potential eco- and animal-friendly meat substitute which has the potential to eradicate animal cruelty and reduce both the environmental footprint and the risk of zoonotic illnesses, while delivering a nutrient-dense product. The purpose of this study was to investigate how consumers perceive cultured meat and if the frequency of meat consumption is related to their intention of trying or purchasing cultured meat. Data were collected online in 2020 from Croatia, Greece, and Spain. Among the 2007 respondents, three segments were identified according to meat consumption and variety, plus an a priori identified group of “non-meat eaters”. Sixty percent perceived cultured meat as kind to animals, 57% as unnatural, 45% as healthy and environmentally-friendly, 21% as disgusting, and only 16% as tasty. Although 47% of the respondents had not heard of cultured meat before, 47% would taste it and 41% would purchase it for the same price as conventional meat. This indicates that consumers from Croatia, Greece and Spain might be likely to purchase cultured meat if sold at an affordable price. 相似文献
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Gobejishvili Nino Gogilashvili Tamar Khechuashvili Sofio Nikoladze Sopio Shanava Zita Tserodze Ana Kukuladze Tea Bakradze Marika Makaridze Lali 《Clinical rheumatology》2022,41(3):935-937
Clinical Rheumatology - The program’s goal is to launch the platform of positive perspectives for people who are suffering from/working in rheumatic and musculoskeletal diseases through the... 相似文献
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Kihara Eunice Galic Ivan Nyamunga Donna Mehdi Fuad Velandia Palacio Luz Andrea Cameriere Roberto 《International journal of legal medicine》2022,136(5):1495-1506
International Journal of Legal Medicine - This study aimed to validate the accuracy of five different formulas based on the Cameriere method for age estimation in Kenyan children. We analyzed... 相似文献