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排序方式: 共有495条查询结果,搜索用时 15 毫秒
1.
Takuya Onizuka M.D. Noriyoshi Sumiya M.D. Ryosuke Aoyama M.D. Yasuhiko Fukuya M.D. Takao Jinnai M.D. 《Aesthetic plastic surgery》1990,14(1):207-213
The results of repairing cleft lip by aesthetic plastic surgery are now excellent. However, the cleft lipnose deformity is still very difficult to repair with the present techniques. A technique that can repair the cleft lip-nose deformity with good results is presented. The technique is divided into three parts: Part I consists of nasal repair of the primary cleft lip. Part II is nasal reconstruction as a secondary operation with or without lip repair. For example, nasal reconstruction may be secondary to repair of deformities of the sill, rim, limen nasi, septum, or nasal bones. Part III is an aesthetic nasal operation such as rhinoplasty, mentoplasty, or zygomaplasty. 相似文献
2.
S Uchida M Sumiya Y Muramatsu Y Ohmomo S Yamaguchi H Obata M Umebayashi 《Health physics》1988,55(5):779-782
Among the routes of gaseous I transfer to rice grains, direct deposition to the hull of rice plants and the subsequent transfer to brown rice and polished rice should be more critical than leaf absorption-translocation. A grain number normalized deposition velocity (Vs) is recommended as a key parameter to assess the amount of gaseous I deposited on the rough rice. This parameter is given as "iodine content per unit number of grain per unit time" divided by "iodine concentration per unit volume of the air." After the heading period the surface area of rough rice is almost constant but weight increases with time. Therefore, mass normalized deposition velocity (VD) varies with time. By introducing Vs instead of VD, the variations could be converged into narrow ranges. The contribution of gaseous I from the atmosphere to rough rice, brown rice and polished rice were estimated using Vs values obtained experimentally and gaseous I concentration in the air. 相似文献
3.
Clinical Implication of CXCL12 Expression in Gastric Cancer 总被引:1,自引:0,他引:1
Ishigami S Natsugoe S Okumura H Matsumoto M Nakajo A Uenosono Y Arigami T Uchikado Y Setoyama T Arima H Hokita S Aikou T 《Annals of surgical oncology》2007,14(11):3154-3158
PURPOSE: Recent research has revealed that tumor cells expressing chemokine receptors have a crucial impact on patient survival. However, there is no information regarding chemokine expression in gastro-intestinal cancer. This study immunohistochemically investigated CXCL12 expression in gastric cancer and evaluated its association with clinical factors, including patient prognosis. METHOD: A total of 185 gastric cancer patients receiving curative gastrectomy were assessed. CXCL12 expression was evaluated by immunohistochemical analysis. Tumors with CXCL12-positive cancer cells were regarded as CXCL12 positive, and according to the degree of CXCL12 expression, patients were divided into three groups (weak, 31 cases; moderate, 27 cases; strong, 20 cases). Correlations between CXCL12 expression and clinical factors in gastric cancer were then determined. RESULTS: CXCL12 was found in the cellular membrane of cancer cells. Seventy-four of 185 patients were classified into the CXCL12-positive group. Patients were divided into three groups according to the positivity of CXCL12 expression. Significant associations between CXCL12 and lymph node metastases (p < 0.05), depth of invasion (p < 0.01), lymphatic invasion (p < 0.01), tumor diameter (p < 0.05), and clinical stage (p < 0.01) were seen. Univariate analysis revealed that the CXCL12-positive group had significantly poorer surgical outcome than the CXCL12-negative group (p < 0.01). Multivariate analysis revealed CXCL12 to be an independent prognostic factor in gastric cancer (p = 0.02). CONCLUSION: Cancerous CXCL12 positivity was determined to be an independent prognostic factor in gastric cancer, with CXCL12-positive gastric cancer showing more-aggressive behavior. Autocrine CXCL12 secretion from tumor cells may activate CXCR-4 on the tumor cells, which may be related to of the viability of distant metastases. 相似文献
4.
Sumiya Ishigami M.D. Shoji Natsugoe M.D. Yoshikazu Uenosono M.D. Yoichi Hata M.D. Aikihiro Nakajo M.D. Futoshi Miyazono M.D. Masataka Matsumoto M.D. Shuichi Hokita M.D. Takashi Aikou M.D. 《Journal of gastrointestinal surgery》2003,7(6):735-739
The sentinel node (SN) is regarded as the first drainage lymph node, and tumor cells are considered likely to directly affect
the SN. However, few reports have identified differences between SNs and non-SNs in cancer patients. Subjects in this study
included 27 patients with gastric cancer who underwent curative operation and intraoperative detection of SNs by radioisotope
methods. The mean number of SNs was 3.2 (range 1 to 5). Degree of infiltration of natural killer cells, dendritic cells, MIB-1
labeling index, and CD3-ξ expression of lymphocytes in SNs and non-SNs were examined by means of immunohistochemical methods.
Degree of infiltration was compared according to depth of invasion and between SNs and non-SNs. Patients with early-stage
cancer displayed a greater degree of infiltration of MIB-1 labeling index and CD3-ξ expression than patients with pT2 or pT3
lesions (P<0.05). The MIB-1 labeling index in SNs was significantly lower than that in non-SNs (P<0.05). However, no significant difference was observed in infiltration of natural killer cells, dendritic cells, or CD3-ξ.
Morphologic changes of dendritic cells in SNs were not definite. Our results suggest that SNs in gastric cancer might not
be suppressed, unlike in breast cancer and melanoma. SN paralysis may depend on tumor- and organ-specific characteristics
or exogenous stimulation from the gastric mucosa. Studies in progress will help to identify immunologic paralysis of the SN
in various types of cancer. Attention must therefore be paid to organ specificity. 相似文献
5.
Kentaro Umezu Naoji Hanayama Akihiko Toyama Kyoko Hobo Arifumi Takazawa 《General thoracic and cardiovascular surgery》2009,57(10):544-546
We report a rare case of a 65-year-old woman who underwent an emergent lifesaving heart operation for an undiagnosed right
coronary artery aneurysm with a coronary arteriovenous fistula complicated by active infective endocarditis, which affected
the aortic valve, mitral valve, and coronary sinus. We performed direct closure of the coronary arteriovenous fistula, ligation
of the right coronary artery aneurysm, double coronary artery bypass grafting, and double valvular replacement. Five years
after the operation, she had no sign of congestive heart failure or infection, and was not receiving antibiotics. 相似文献
6.
Protein-Losing Enteropathy in Systemic Lupus Erythematosus 总被引:3,自引:0,他引:3
Shojiro Takagi M.D. Kazuo Oshimi M.D. Morito Sumiya M.D. Nobuyuki Gonda M.D. Shogo Kano M.D. Fumimaro Takaku M.D. 《The American journal of gastroenterology》1983,78(3):152-154
Although protein-losing enteropathy can be associated with a variety of disorders, only three cases have been described in association with systemic lupus erythematosus. In the case described herein, protein-losing enteropathy was the only clinical manifestation of systemic lupus erythematosus. Small intestinal biopsy revealed edema and mild mononuclear cell infiltration in lamina propria mucosae and no evidence of lymphangiectasia. X-ray studies of the gastrointestinal tract were normal. Protein-losing enteropathy responded to high-dose corticosteroid therapy. Protein-losing enteropathy should be suspected as a possible cause of unexplained hypoalbuminemia in systemic lupus erythematosus. 相似文献
7.
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9.
Sumiya Aihemaitijiang Chen Ye Mairepaiti Halimulati Xiaojie Huang Ruoyu Wang Zhaofeng Zhang 《Nutrients》2022,14(5)
(1) Background: Improving nutrition literacy is crucial for maintaining a healthier state of the elderly to achieve healthy ageing. Therefore, it is necessary to develop a Nutrition Literacy Questionnaire for the Chinese Elderly (NLQ-E). (2) Methods: an NLQ-E was developed according to the core components of nutrition literacy for the elderly. Internal consistency, exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to validate the reliability and validity of the NLQ-E. A cross-sectional study of 1490 elderly people was used to analyze the application of the NLQ-E. (3) Results: The NLQ-E was constructed with 3 domains (knowledge and understanding, healthy lifestyle and dietary behavior and skill), with a total of 25 questions. The overall NLQ-E had acceptable reliability and validity (Cronbach’s α = 0.678, χ2/DF = 4.750, RMSEA = 0.045, PCFI = 0.776 and PNFI = 0.759). The average nutrition literacy score of the subjects in this cross-sectional study was 65.95 (65.95 ± 10.93). The OR between the nutrition literacy score and multimorbidity was 0.965 (95% CI: 0.954, 0.976); (4) Conclusions: We developed and validated the NLQ-E and found that the nutrition literacy level of the Chinese elderly was generally low. This study is of great value to improve the nutrition literacy of the elderly and effectively prevent nutrition-related chronic diseases and multimorbidity. 相似文献
10.
Intraoperative dorsal language network mapping by using single‐pulse electrical stimulation 下载免费PDF全文
Yukihiro Yamao Riki Matsumoto Takeharu Kunieda Yoshiki Arakawa Katsuya Kobayashi Kiyohide Usami Sumiya Shibata Takayuki Kikuchi Nobukatsu Sawamoto Nobuhiro Mikuni Akio Ikeda Hidenao Fukuyama Susumu Miyamoto 《Human brain mapping》2014,35(9):4345-4361
The preservation of language function during brain surgery still poses a challenge. No intraoperative methods have been established to monitor the language network reliably. We aimed to establish intraoperative language network monitoring by means of cortico‐cortical evoked potentials (CCEPs). Subjects were six patients with tumors located close to the arcuate fasciculus (AF) in the language‐dominant left hemisphere. Under general anesthesia, the anterior perisylvian language area (AL) was first defined by the CCEP connectivity patterns between the ventrolateral frontal and temporoparietal area, and also by presurgical neuroimaging findings. We then monitored the integrity of the language network by stimulating AL and by recording CCEPs from the posterior perisylvian language area (PL) consecutively during both general anesthesia and awake condition. High‐frequency electrical stimulation (ES) performed during awake craniotomy confirmed language function at AL in all six patients. Despite an amplitude decline (≤32%) in two patients, CCEP monitoring successfully prevented persistent language impairment. After tumor removal, single‐pulse ES was applied to the white matter tract beneath the floor of the removal cavity in five patients, in order to trace its connections into the language cortices. In three patients in whom high‐frequency ES of the white matter produced naming impairment, this “eloquent” subcortical site directly connected AL and PL, judging from the latencies and distributions of cortico‐ and subcortico‐cortical evoked potentials. In conclusion, this study provided the direct evidence that AL, PL, and AF constitute the dorsal language network. Intraoperative CCEP monitoring is clinically useful for evaluating the integrity of the language network. Hum Brain Mapp 35:4345–4361, 2014. © 2014 Wiley Periodicals, Inc . 相似文献