全文获取类型
收费全文 | 7815篇 |
免费 | 474篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 97篇 |
儿科学 | 684篇 |
妇产科学 | 138篇 |
基础医学 | 955篇 |
口腔科学 | 192篇 |
临床医学 | 484篇 |
内科学 | 1418篇 |
皮肤病学 | 302篇 |
神经病学 | 532篇 |
特种医学 | 207篇 |
外科学 | 808篇 |
综合类 | 202篇 |
一般理论 | 3篇 |
预防医学 | 424篇 |
眼科学 | 377篇 |
药学 | 762篇 |
中国医学 | 30篇 |
肿瘤学 | 698篇 |
出版年
2023年 | 53篇 |
2022年 | 136篇 |
2021年 | 308篇 |
2020年 | 188篇 |
2019年 | 217篇 |
2018年 | 290篇 |
2017年 | 152篇 |
2016年 | 214篇 |
2015年 | 223篇 |
2014年 | 349篇 |
2013年 | 402篇 |
2012年 | 594篇 |
2011年 | 572篇 |
2010年 | 328篇 |
2009年 | 269篇 |
2008年 | 381篇 |
2007年 | 355篇 |
2006年 | 343篇 |
2005年 | 306篇 |
2004年 | 270篇 |
2003年 | 211篇 |
2002年 | 180篇 |
2001年 | 158篇 |
2000年 | 130篇 |
1999年 | 118篇 |
1998年 | 57篇 |
1997年 | 37篇 |
1996年 | 49篇 |
1995年 | 38篇 |
1994年 | 49篇 |
1993年 | 39篇 |
1992年 | 86篇 |
1991年 | 94篇 |
1990年 | 95篇 |
1989年 | 81篇 |
1988年 | 70篇 |
1987年 | 79篇 |
1986年 | 60篇 |
1985年 | 64篇 |
1984年 | 65篇 |
1983年 | 48篇 |
1982年 | 64篇 |
1981年 | 72篇 |
1980年 | 74篇 |
1979年 | 55篇 |
1978年 | 36篇 |
1977年 | 28篇 |
1976年 | 32篇 |
1973年 | 32篇 |
1970年 | 27篇 |
排序方式: 共有8313条查询结果,搜索用时 31 毫秒
1.
Kevin Kyung Ho Choi Santosh Sanagapalli 《World journal of gastrointestinal oncology》2022,14(3):568-586
Barrett's esophagus (BE) is the precursor to esophageal adenocarcinoma (EAC). Progression to cancer typically occurs in a stepwise fashion through worsening dysplasia and ultimately, invasive neoplasia. Established EAC with deep involvement of the esophageal wall and/or metastatic disease is invariably associated with poor long-term survival rates. This guides the rationale of surveillance of Barrett’s in an attempt to treat lesions at an earlier, and potentially curative stage. The last two decades have seen a paradigm shift in management of Barrett’s with rapid expansion in the role of endoscopic eradication therapy (EET) for management of dysplastic and early neoplastic BE, and there have been substantial changes to international consensus guidelines for management of early BE based on evolving evidence. This review aims to assist the physician in the therapeutic decision-making process with patients by comprehensive review and summary of literature surrounding natural history of Barrett’s by histological stage, and the effectiveness of interventions in attenuating the risk posed by its natural history. Key findings were as follows. Non-dysplastic Barrett’s is associated with extremely low risk of progression, and interventions cannot be justified. The annual risk of cancer progression in low grade dysplasia is between 1%-3%; EET can be offered though evidence for its benefit remains confined to highly select settings. High-grade dysplasia progresses to cancer in 5%-10% per year; EET is similarly effective to and less morbid than surgery and should be routinely performed for this indication. Risk of nodal metastases in intramucosal cancer is 2%-4%, which is comparable to operative mortality rate, so EET is usually preferred. Submucosal cancer is associated with nodal metastases in 14%-41% hence surgery remains standard of care, except for select situations. 相似文献
2.
3.
Toshiro Hara Rony Chanoch-Myers Nathan D. Mathewson Chad Myskiw Lyla Atta Lillian Bussema Stephen W. Eichhorn Alissa C. Greenwald Gabriela S. Kinker Christopher Rodman L. Nicolas Gonzalez Castro Hiroaki Wakimoto Orit Rozenblatt-Rosen Xiaowei Zhuang Jean Fan Tony Hunter Inder M. Verma Kai W. Wucherpfennig Itay Tirosh 《Cancer cell》2021,39(6):779-792.e11
- Download : Download high-res image (228KB)
- Download : Download full-size image
4.
Rajesh Verma Puneet Kumar Dixit Rakesh Lalla Babita Singh 《Annals of Indian Academy of Neurology》2015,18(2):246-248
Mirror movements are simultaneous, involuntary, identical movements occurring during contralateral voluntary movements. These movements are considered as soft neurologic signs seen uncommonly in clinical practice. The mirror movements are described in various neurological disorders which include parkinsonism, cranio veretebral junction anamolies, and hemiplegic cerebral palsy. These movements are intriguing and can pose significant disability. However, no such observation regarding mirror movements in progressive hemifacial atrophy have been reported previously. We are reporting a teenage girl suffering from progressive hemifacial atrophy and epilepsy with demonstrable mirror movements in hand. 相似文献
5.
6.
7.
8.
Ashok Verma Mazin Al Khabori Rajiv Zutshi 《Indian journal of otolaryngology and head and neck surgery》2006,58(1):9-14
This is a prospective, non-randomized study to evaluate and compare the results, morbidity and surgical time for endonasal carbon-dioxide laser assisted dacryocystorhinostomy and external dacryocystorhinostomy. 70 consecutive patients of chronic dacryocystitis with nasolacrimal duct obstruction were selected for the study. 36 patients under went endonasal CO2 laser assisted dacryocystorhinostomy and 34 had external dacryocystorhinostomy. Selection of the type of operation was left to the patient's choice. All the patients had preoperative counseling and both the procedures were explained in detail with their advantages and disadvantages. Patients not willing for the external incision were selected for endonasal laser assisted dacryocystorhinostomy and others were operated via external approach. Silicone tubes were put in all the patients for three months after surgery. The final follow up was 12 months after the removal of silicone tubes. The patency of the lacrimal passage was confirmed by irrigation, and patients were questioned about their symptoms. The success rates, 12 months after removal of silicone tubes were 100% in endonasal CO2 laser assisted dacryocystorhinostomy and 88.24% in external dacryocystorhinostomy. The surgical time of endonasal laser assisted dacryocystorhinostomy was 38 minutes as compared to 62 in external dacryocystorhinostomy. Complication rate in both groups was almost equal. Thus, we came to the conclusion that Endonasal CO2 laser assisted dacryocystorhinostomy is a better surgical option to external dacryocystorhinostomy in cases of chronic dacryocystitis with nasolacrimal duct obstruction, with shorter surgical time. 相似文献
9.
Ravinder Verma 《Indian journal of otolaryngology and head and neck surgery》1996,48(4):312-314
Stylalgia is an important cause of paroxysmal dull pain in the throat and ear. Enlarged styloid process is the ossification stylohyoid ligament. Pain is aggravated by the act of deglutition. Pain due to enlarged styloid process may be attributed to the Glassopharyngeal Neuritis or stiff bony clasp formation. Styloidectomy, by any route, is a satisfactory mode of treatment in such cases. In cases with prolonged illness or no response with styloidectomy, Glassopharyngeal Neurectomy may be taken up. 相似文献
10.
Complete dislocation of the lens is a rare feature of Marfan's Syndrome. We observed four cases of bilateral complete posterior dislocation of the lens in established cases of Marfan's Syndrome over a one year period. An ophthalmologist may encounter infrequently, unilateral posterior dislocation in one eye and ectopia lentis in the other, but bilateral spontaneous posterior dislocation is rare. All our cases had associated vitreous degeneration with vitreous herniating into the anterior chamber. The pathogenesis of complete posterior dislocation in Marfan's Syndrome is discussed. 相似文献