全文获取类型
收费全文 | 10290篇 |
免费 | 662篇 |
国内免费 | 36篇 |
专业分类
耳鼻咽喉 | 53篇 |
儿科学 | 292篇 |
妇产科学 | 176篇 |
基础医学 | 1931篇 |
口腔科学 | 259篇 |
临床医学 | 878篇 |
内科学 | 2130篇 |
皮肤病学 | 298篇 |
神经病学 | 1292篇 |
特种医学 | 356篇 |
外科学 | 892篇 |
综合类 | 55篇 |
一般理论 | 7篇 |
预防医学 | 609篇 |
眼科学 | 171篇 |
药学 | 606篇 |
中国医学 | 19篇 |
肿瘤学 | 964篇 |
出版年
2023年 | 62篇 |
2022年 | 138篇 |
2021年 | 234篇 |
2020年 | 187篇 |
2019年 | 251篇 |
2018年 | 298篇 |
2017年 | 187篇 |
2016年 | 287篇 |
2015年 | 307篇 |
2014年 | 400篇 |
2013年 | 518篇 |
2012年 | 759篇 |
2011年 | 807篇 |
2010年 | 424篇 |
2009年 | 443篇 |
2008年 | 663篇 |
2007年 | 715篇 |
2006年 | 662篇 |
2005年 | 651篇 |
2004年 | 616篇 |
2003年 | 564篇 |
2002年 | 476篇 |
2001年 | 101篇 |
2000年 | 98篇 |
1999年 | 122篇 |
1998年 | 141篇 |
1997年 | 86篇 |
1996年 | 75篇 |
1995年 | 66篇 |
1994年 | 52篇 |
1993年 | 39篇 |
1992年 | 47篇 |
1991年 | 37篇 |
1990年 | 37篇 |
1989年 | 41篇 |
1988年 | 34篇 |
1987年 | 48篇 |
1986年 | 24篇 |
1985年 | 40篇 |
1984年 | 20篇 |
1983年 | 20篇 |
1981年 | 13篇 |
1979年 | 23篇 |
1978年 | 10篇 |
1977年 | 10篇 |
1975年 | 10篇 |
1974年 | 16篇 |
1973年 | 14篇 |
1972年 | 20篇 |
1971年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
Patient history and clinical examination are important for the diagnosis of degenerative joint disease. Here the typical statements of a patient suffering from early osteoarthritis are described and, as far as possible, explained. The joint in question must be systematically examined. Furthermore, the neighboring joints and soft-tissue structures, i.e., muscles, tendons etc., should be examined and evaluated with respect to their importance in hindering the functional chain. The neuroreflectory mechanisms involved herein are described. 相似文献
7.
In this study newly diagnosed male and female lung cancer patients admitted to two Ontario Cancer Foundation treatment clinics were interviewed. Information was obtained on demographic variables, presence of other chronic illness and the following psychosocial attributes: locus of control, social support and personality traits. From the clinic charts, information on stage of disease and pathological diagnosis was obtained. After controlling for the effects of stage and pathological diagnosis, the following psychological variables were found to increase the odds of death from lung cancer among males and females combined at one year after diagnosis: a high need for one aspect of social support, a reserved personality and the extremes of the personality trait soberness vs enthusiasm. 相似文献
8.
Prof. Dr. Wolfgang Dörr Sabine Köst Klaus Keinert Felix-Herbert Glaser Gerd Endert Thomas Herrmann 《Strahlentherapie und Onkologie》2006,182(1):1-8
PURPOSE: To compare tests for intestinal function with clinical scores after abdominal irradiation. PATIENTS AND METHODS: At the Department of Radiotherapy, Erfurt, Germany, intestinal changes were studied in 91 patients receiving abdominal radiotherapy between 1992 and 1996. Conventional fractionation (1.8-2 Gy per fraction, total doses 30.6-62.5 Gy) was applied. Before and at weekly intervals during radiotherapy, the clinical response was scored according to RTOG/EORTC for the upper and lower gastrointestinal (GI) tract. Resorption tests for vitamin B(12) and D-xylose were performed before the onset and immediately after treatment. RESULTS: The clinical response displayed a well-defined dose-effect relationship with grade 1 effects in 5% and 50% of the patients at about 10 Gy and 50 Gy, respectively. For grade 2 reactions, 5%- and 50%-effective doses were 20-30 Gy and 60-80 Gy. Effects in the upper and lower GI tract were highly correlated. Changes in body weight did not show a correlation with other clinical symptoms. Changes in resorption also displayed a significant dose effect. However, no correlation was found with the clinical symptoms in the individual patient. CONCLUSION: In the present study, the clinical manifestation of intestinal side effects according to RTOG/EORTC criteria was reflected by neither the vitamin B(12) nor by the D-xylose resorption test. Hence, these tests cannot be regarded as useful for objective quantitation of intestinal radiation injury. 相似文献
9.
Cytoskeletal association of human alpha-interferon-receptor complexes in interferon-sensitive and -resistant lymphoblastoid cells. 总被引:6,自引:2,他引:4
下载免费PDF全文
![点击此处可从《Proceedings of the National Academy of Sciences of the United States of America》网站下载免费的PDF全文](/ch/ext_images/free.gif)
L M Pfeffer N Stebbing D B Donner 《Proceedings of the National Academy of Sciences of the United States of America》1987,84(10):3249-3253
Human Daudi lymphoblastoid cells, which are highly sensitive to the antiproliferative action of human leukocyte alpha-interferon (IFN-alpha), and IFN-resistant and IFN-sensitive Daudi subclones (Cl2 and Cl1, respectively), contain 2300 (Kd = 20 X 10(-12) M), 3000 (Kd = 45 X 10(-12) M), and 3700 (Kd = 52 X 10(-12) M) IFN-alpha binding sites per cell, respectively. Thus, these IFN-sensitive and IFN-resistant cells have similar numbers of high-affinity IFN-alpha receptors. IFN-receptor complexes that are insoluble in Triton X-100 accumulate in IFN-sensitive but not in IFN-resistant cells. The ligand-induced accumulation of Triton-insoluble complexes in IFN-sensitive cells was inhibited by cytochalasin B. This suggests that the solubility change of IFN-receptor complexes results from their interaction with the cytoskeletal matrix. The dissociation of IFN-alpha from IFN-sensitive and IFN-resistant cells can be resolved into fast and slow components. IFN-alpha dissociates more slowly from IFN-sensitive cells than from IFN-resistant cells. Very slow dissociation of IFN-alpha from Triton-insoluble complexes correlates with this difference. These observations suggest that IFN-receptor complexes become coupled to the cytoskeletal matrix in IFN-sensitive but not in IFN-resistant cells, and that such interaction is an important element in the mechanism of the antiproliferative action of IFN-alpha on Daudi cells. 相似文献
10.