全文获取类型
收费全文 | 3317篇 |
免费 | 145篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 42篇 |
儿科学 | 74篇 |
妇产科学 | 60篇 |
基础医学 | 451篇 |
口腔科学 | 360篇 |
临床医学 | 261篇 |
内科学 | 640篇 |
皮肤病学 | 43篇 |
神经病学 | 324篇 |
特种医学 | 68篇 |
外科学 | 267篇 |
综合类 | 10篇 |
一般理论 | 1篇 |
预防医学 | 392篇 |
眼科学 | 61篇 |
药学 | 306篇 |
中国医学 | 44篇 |
肿瘤学 | 79篇 |
出版年
2023年 | 29篇 |
2022年 | 79篇 |
2021年 | 129篇 |
2020年 | 72篇 |
2019年 | 121篇 |
2018年 | 113篇 |
2017年 | 77篇 |
2016年 | 99篇 |
2015年 | 94篇 |
2014年 | 131篇 |
2013年 | 159篇 |
2012年 | 247篇 |
2011年 | 254篇 |
2010年 | 159篇 |
2009年 | 122篇 |
2008年 | 181篇 |
2007年 | 181篇 |
2006年 | 148篇 |
2005年 | 141篇 |
2004年 | 116篇 |
2003年 | 106篇 |
2002年 | 82篇 |
2001年 | 58篇 |
2000年 | 60篇 |
1999年 | 43篇 |
1998年 | 9篇 |
1997年 | 11篇 |
1994年 | 8篇 |
1992年 | 26篇 |
1991年 | 21篇 |
1990年 | 34篇 |
1989年 | 20篇 |
1988年 | 24篇 |
1987年 | 13篇 |
1986年 | 23篇 |
1985年 | 24篇 |
1984年 | 18篇 |
1983年 | 15篇 |
1982年 | 13篇 |
1979年 | 23篇 |
1978年 | 14篇 |
1977年 | 15篇 |
1976年 | 10篇 |
1974年 | 12篇 |
1973年 | 12篇 |
1972年 | 13篇 |
1971年 | 9篇 |
1969年 | 20篇 |
1968年 | 17篇 |
1967年 | 11篇 |
排序方式: 共有3483条查询结果,搜索用时 0 毫秒
1.
F Pithon 《Bulletin des sociétés d'ophtalmologie de France》1990,90(5):561-568
A new approach for the treatment of serious and/or uncurable glaucoma is proposed by the adjonction of a drain, cut in a crinotube, with micro-perforations and set in the classical opening of a trabeculectomy. In four years, for nine cases of particularly severe hypertonia, we observed one relative unsuccess, three real and stable improvements during two years and then with the necessity of local treatment (for rather young patients), and five clear and till today durable improvements. We have also observed a very good local tolerance for all cases, with never a persisting major hypotonia. This simple and efficient process seams susceptible to find its room in the treatment of severe hypertonia. 相似文献
2.
The laryngeal mask in failed intubation 总被引:1,自引:0,他引:1
3.
4.
Dennis M Mello MD Doff B McElhinney MS Andrew J Parry MD Norman H Silverman MD Frank L Hanley MD 《The Annals of thoracic surgery》1997,64(6):1808-1810
In hearts with a common arterial trunk (truncus arteriosus), there is almost always an inverse development of the aortic arch and the ductus arteriosus. Truncus with a normal aortic arch and a patent ductus is a rare echocardiographic and surgical finding. In this report, we describe 2 neonates in whom truncus arteriosus with a normal aortic arch and a medium or large patent ductus was diagnosed by preoperative echocardiography (without catheterization) and confirmed intraoperatively. 相似文献
5.
E P A Lopes E C Gouveia A C C Albuquerque L H B C Sette L A Mello R C Moreira M R C D Coelho 《Journal of clinical virology》2006,35(3):298-302
BACKGROUND: Elevated liver enzymes are infrequent in patients with hepatitis C virus (HCV) infection undergoing chronic hemodialysis (HD), suggesting that the alanine aminotransferase (ALT) is a poor predictor of hepatocellular damage in this population. OBJECTIVE: To establish a more appropriate cut-off value of ALT to identify biochemical activity due to HCV infection in HD patients. STUDY DESIGN: A total of 217 patients, with an average age of 51.2 years, were evaluated between January and October 2002; 130 were males (60%). Serum ALT was measured by a kinetic method in five consecutive monthly blood samples, from which an average was obtained and divided by the upper limit of normal (ULN). HCV antibodies were determined using an enzyme immunoassay, the serum HCV-RNA by nested-PCR and HCV genotype by hybridization of the amplified sequence from the 5'-non-coding region. The cut-off value of ALT was obtained from a ROC curve. RESULTS: Within the 217 patients, 18 (8.3%) were anti-HCV-positive, 17 (7.8%) of whom were also HCV-RNA-positive. Genotype distribution was: 1a=47%; 1b=18%; 3a=35%. Mean ALT/ULN (0.77+/-0.57) of the 18 anti-HCV-positive cases was higher (p<0.001) than the negative group (0.38+/-0.23). The mean ALT/ULN (0.81+/-0.57) of the 17 HCV-RNA-positive cases was also higher (p<0.0001) than the negative cases (0.37+/-0.23). The cut-off value of ALT to distinguish the anti-HCV-positive from negative patients was 0.50% or 50% of the ULN (sensitivity=67%; specificity=83%). According to the HCV-RNA, the cut-off value of ALT was 0.45% or 45% of the ULN (sensitivity=71%; specificity=80%). CONCLUSION: Reducing the cut-off of ALT by half, enables a better identification of biochemical activity in patients with HCV infection on chronic HD. 相似文献
6.
Kaster MP Rosa AO Rosso MM Goulart EC Santos AR Rodrigues AL 《Neuroscience letters》2004,355(1-2):21-24
This study investigated the effect of adenosine in the forced swimming test (FST) and the tail suspension test (TST) in mice, and the contribution of adenosine A1 and A2A receptors to adenosine's antidepressant-like effect. The immobility time in the FST was reduced by adenosine given either by i.p. (5-10 mg/kg) or i.c.v. (0.01-10 microg/site) route. Adenosine (1-10 mg/kg, i.p.) also produced an antidepressant-like effect in the TST. No treatment affected locomotion in an open-field. The anti-immobility effect of adenosine (10 mg/kg, i.p.) in the FST was prevented by i.p. pretreatment of mice with caffeine (3 mg/kg), DPCPX (2 mg/kg) and ZM241385 (1 mg/kg). CHA (0.05 mg/kg, i.p.) and DPMA (1-5 mg/kg, i.p.) also produced an antidepressant-like effect in the FST. This is the first report of an antidepressant-like effect of adenosine in mice, apparently mediated through an interaction with A1 and A2A receptors. 相似文献
7.
8.
Filho OG Gordan AN Mello Rde A Neto CS Heinke T 《International journal of surgical pathology》2004,12(2):151-153
Hamartomas were first described by Albrecht in 1904, who defined them as tumor-like malformations in which there was abnormal blending of the normal components of an organ. The myoid hamartoma is a rare benign lesion of the breast and has an uncertain origin, possibly in the walls of the blood vessels, muscularis mammillae of the areolae, and mainly in myoepithelium. We report 3 cases of myoid hamartomas of the breast, with the clinical, radiologic, and histopathological findings, and review the literature. The 3 lesions showed normal breast ducts and lobules, entrapped by a muscular stroma and some foci of mature adipose tissue. The muscular origin of part of the stroma was confirmed by strong reactiveness with smooth-muscle actin. 相似文献
9.
10.
Assumpção JG Berkofsky-Fessler W Viguetti Campos N Trevas Maciel-Guerra A Li S Melaragno MI Palandi de Mello M Warburton PE 《American journal of medical genetics》2002,113(3):263-267
An 18-year-old woman was evaluated because of primary amenorrhea and hypogonadism. Chromosome analysis from peripheral blood lymphocytes revealed a nonmosaic 46,X,+mar constitution. The marker was shown to be a rearranged Y chromosome consisting of an inverted duplication of the long arm: rea(Y)(qter-q11::q11-qter). Deletion mapping analysis with Y-specific STS showed that the marker lacked Yp and Y-centromeric (DYZ3) sequences, but it was positive for Yq sequences tested. Fluorescence in situ hybridization analysis with Y and X chromosome centromeric and pancentromeric probes showed no hybridization signals. The marker chromosome is present in 100% of the cells; therefore, it is mitotically stable despite the absence of DYZ3 centromeric sequence. Hybridization with CENP-A and CENP-C specific antibodies localized a neocentromere close to the breakpoint. 相似文献