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F A Rustamov A M Kazenkov N N Smirnova N V Bo?kova K M Sergeeva M N Maslova 《Patologicheskaia fiziologiia i èksperimental'naia terapiia》1991,(5):37-39
The authors undertook comparative study of the Na, K-ATPase activity in the red cells, ghost corpuscles, and in the cortex and medulla of kidneys of rats with experimental glomerulonephritis (GN) induced by injection of nephrotoxic serum (NTS), during an acute course of the process (1 and 2 weeks after NTS injection) and in chronic affection of the kidneys (10 weeks after NTS injection). The activity of the enzyme both in the red cells and in the ghost corpuscles was reduced significantly, by 28 and 22%, respectively, in the acute period of the disease (one week after NTS injection) but was restored to normal values in the period of chronic affection of the kidneys. The activity of the enzyme did not change in the cortex during the whole period of the study, but in the medulla it diminished in the acute period of the disease and remained reduced (by 27% on the average) during the chronic phase. It is concluded that reduction of the enzyme activity in the studied objects was not caused by the presence of endogenous inhibitors of the enzyme. It is suggested that reduction of Na, K-ATPase activity in the renal medulla may be one of the factors of increase of Na and water excretion in the urine in the chronic phase of GN. 相似文献
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Yu. B. Lishmanov L. V. Maslova L. N. Maslov E. N. Dan'shina 《Bulletin of experimental biology and medicine》1993,116(2):974-976
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N
o
8, pp. 175–176, August, 1993 相似文献
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Maslova MV Maklakova AS Sokolova NA Ashmarin IP Goncharenko EN Krushinskaya YV 《Neuroscience and behavioral physiology》2003,33(6):607-611
Ante- and postnatal hypoxia significantly worsened the postnatal development of animals. The posthypoxic behavioral model included hyperactivity and decreased learning ability, these being typical manifestations of attention deficit disorder. A peptide constellation prevented and significantly improved posthypoxic postnatal development and eliminated the majority of negative behavioral changes. 相似文献
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G. S. Yakobson A. R. Antonov G. V. Petrova L. N. Maslova A. L. Markel' 《Bulletin of experimental biology and medicine》1996,121(5):449-451
Endocrine functions were investigated in normotensive (Wistar) and hypertensive (NISAG) rats before and on days 3, 7, and
21 after subcutaneous epinephrine administration. Rats of the NISAG strain are characterized by elevated plasma levels of
aldosterone and thyroxine and lowered plasma levels of immunoreactive insulin, and their endocrine system develops a much
stronger response to a single epinephrine injection than does that of Wistar rats. This is manifested in a still higher aldosterone
level, elevated corticosterone and insulin concentrations, and reduced thyroxine content in the plasma.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 5, pp. 495–498, May, 1996 相似文献
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The paper considers how to obtain quantitative characteristics of sensomotor responses while tracing, learning, and reproducing rhythmical stimuli of different frequency and modality which can be used to assess psychomotor activity, perception, attention, short-term memory in schoolchildren with infantile cerebral paralysis. The results of examinations of children with this condition are given and analyzed. 相似文献
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Intensive maturation of arbitrary attention occurs in the making of higher mental functions in children in transition to schooling. The study has yielded standard indices of changes in some higher mental functions at the age of 6-8 years, which makes it possible to make a timely objective diagnosis in mental and neurological practice to predict the child's development, and to provide a required complex of medical and pedagogical corrective measures. 相似文献