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排序方式: 共有90条查询结果,搜索用时 15 毫秒
1.
Guilmot Antoine Maldonado Slootjes Sofia Sellimi Amina Bronchain Maroussia Hanseeuw Bernard Belkhir Leila Yombi Jean Cyr De Greef Julien Pothen Lucie Yildiz Halil Duprez Thierry Fillée Catherine Anantharajah Ahalieyah Capes Antoine Hantson Philippe Jacquerye Philippe Raymackers Jean-Marc London Frederic El Sankari Souraya Ivanoiu Adrian Maggi Pietro van Pesch Vincent 《Journal of neurology》2021,268(3):751-757
Journal of Neurology - Evidence of immune-mediated neurological syndromes associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection is limited. We therefore... 相似文献
2.
Ali US Sengupta K Andankar P Saraf S Chawla A Deshpande S 《Pediatric nephrology (Berlin, Germany)》2004,19(9):1050-1052
Three exclusively breastfed term neonates were admitted with lethargy, poor feeding, and oligoanuria. All three babies were severely dehydrated and had a weight loss ranging from 18% to 40%. Serum sodium of more than 180 mEq/l and renal failure were observed in all three. Two had very high creatinine levels of 9.5 mg/dl and 6.7 mg/dl. Both these babies also had multiple seizures. One baby required mechanical ventilation. All three babies showed markedly hyperechoic renal medullary pyramids with speckled foci suggestive of crystal deposition that reversed completely on therapy. Urine showed abundant urate crystals in two and an elevated calcium/creatinine ratio of 1.6 in one. There was no evidence of distal renal tubular acidosis, Bartter syndrome, or high serum calcium. Supersaturation of the ions in a markedly hypertonic renal medulla may have led to crystallization, with resolubilization with hydration and restoration of good urine output. The hypernatremic dehydration was primarily due to lactation failure leading to inadequate fluid intake in the face of ongoing insensible losses. High breast milk sodium may have been a contributory factor in one patient. 相似文献
3.
Xavier Finné Lenoir Christian Sindic Vincent van Pesch Souraya El Sankari Marianne de Tourtchaninoff Roger Denays Philippe Hantson 《Neurocritical care》2013,18(1):89-92
Background
To describe a case of auto-immune encephalitis in an adolescent with favorable outcome despite prolonged status epilepticus.Methods
A 17 year old Asian man without previous medical history developed alteration of consciousness and partial seizures. The diagnosis of anti-N-methyl-D-aspartate receptor encephalitis was confirmed by the detection of specific antibodies in both cerebrospinal fluid and serum.Results
The clinical course was complicated by prolonged status epilepticus which was refractory to a large number of antiepileptic drugs, including barbiturate coma. Immunomodulatory therapy included steroids, plasma exchanges, and intravenous immunoglobulins. After 86 days of intensive therapy, the patient regained consciousness progressively. Brain magnetic resonance imaging never demonstrated any lesion. Extensive search for a tumor was negative. At 12 month follow-up, the patient had made an excellent recovery.Conclusion
Auto-immune encephalitis is likely underdiagnosed in adolescents. In their most severe presentation, seizures may be resistant to a large number of anti-epileptic drugs, and the clinical improvement seems to be mainly because of the immunomodulatory therapy. Relapse is possible, as well as the delayed development of a teratoma or other tumor. 相似文献4.
5.
B. J. Orandi J. M. Garonzik‐Wang A. B. Massie A. A. Zachary J. R. Montgomery K. J. Van Arendonk M. D. Stegall S. C. Jordan J. Oberholzer T. B. Dunn L. E. Ratner S. Kapur R. P. Pelletier J. P. Roberts M. L. Melcher P. Singh D. L. Sudan M. P. Posner J. M. El‐Amm R. Shapiro M. Cooper G. S. Lipkowitz M. A. Rees C. L. Marsh B. R. Sankari D. A. Gerber P. W. Nelson J. Wellen A. Bozorgzadeh A. O. Gaber R. A. Montgomery D. L. Segev 《American journal of transplantation》2014,14(7):1573-1580
6.
Molecular characterization of β-thalassemia (β-thal) is essential in prevention and in understanding the biology of the disease. Deletion mutations are relatively uncommon in β-thal. In this report, we describe a novel 26 bp deletion from codon 6 to codon 14 in the β-globin in a consanguineous family from Tamil Nadu, India. This novel mutation causes a shift in the normal reading frame of the β-globin coding sequence, and consequently, a premature chain termination of translation due to the creation of a stop codon at the position of codon 21. The identification of this novel deletional mutation adds to the repertoire of β-thal mutations in India. 相似文献
7.
Laparoendoscopic single‐site (LESS) vs laparoscopic living‐donor nephrectomy: a systematic review and meta‐analysis 下载免费PDF全文
Riccardo Autorino Luis Felipe Brandao Bashir Sankari Homayoun Zargar Humberto Laydner Oktay Akça Marco De Sio Vincenzo Mirone Shih‐Chieh J. Chueh Jihad H. Kaouk 《BJU international》2015,115(2):206-215
The aim of this study was to provide a systematic review and meta‐analysis of reports comparing laparoendoscopic single‐site (LESS) living‐donor nephrectomy (LDN) vs standard laparoscopic LDN (LLDN). A systematic review of the literature was performed in September 2013 using PubMed, Scopus, Ovid and The Cochrane library databases. Article selection proceeded according to the search strategy based on Preferred Reporting Items for Systematic Reviews and Meta‐analyses criteria. Weighted mean differences (WMDs) were used to measure continuous variables and odds ratios (ORs) to measure categorical ones. Nine publications meeting eligibility criteria were identified, including 461 LESS LDN and 1006 LLDN cases. There were more left‐side cases in the LESS LDN group (96.5% vs 88.6%, P < 0.001). Meta‐analysis of extractable data showed that LLDN had a shorter operative time (WMD 15.06 min, 95% confidence interval [CI] 4.9–25.1; P = 0.003), without a significant difference in warm ischaemia time (WMD 0.41 min, 95% CI –0.02 to 0.84; P = 0.06). Estimated blood loss was lower for LESS LDN (WMD ?22.09 mL, 95% CI –29.5 to –14.6; P < 0.001); however, this difference was not clinically significant. There was a greater likelihood of conversion for LESS LDN (OR 13.21, 95% CI 4.65–37.53; P < 0.001). Hospital stay was similar (WMD –0.11 days, 95% CI –0.33 to 0.12; P = 0.35), as well as the visual analogue pain score at discharge (WMD –0.31, 95% CI –0.96 to 0.35; P = 0.36), but the analgesic requirement was lower for LESS LDN (WMD –2.58 mg, 95% CI –5.01 to –0.15; P = 0.04). Moreover, there was no difference in the postoperative complication rate (OR 1.00, 95% CI 0.65–1.54; P = 0.99). Renal function of the recipient, as based on creatinine levels at 1 month, showed similar outcomes between groups (WMD 0.10 mg/dL, –0.09 to 0.29; P = 0.29). In conclusion, LESS LDN represents an emerging option for living kidney donation. This procedure offers comparable surgical and early functional outcomes to the conventional LLDN, with a lower analgesic requirement. However, it is more technically challenging than LLDN, as shown by a greater likelihood of conversion. The role of LESS LDN remains to be defined. 相似文献
8.
9.
The success of kidney transplantation has improved over the last decade largely due to new immunosuppressive agents that resulted in decrease in incidence and severity of acute cellular rejection. Minimizing the adverse effects of immunosuppressive agents is essential to improving long-term survival. This article reviews the current immunosuppressive agents available to the clinician, their side effects and interaction with other medications. Current immunosuppressive protocols are also discussed including newer steroid avoidance protocols and calcineurin avoidance protocol. 相似文献
10.