全文获取类型
收费全文 | 6290篇 |
免费 | 492篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 47篇 |
儿科学 | 258篇 |
妇产科学 | 106篇 |
基础医学 | 653篇 |
口腔科学 | 759篇 |
临床医学 | 458篇 |
内科学 | 1280篇 |
皮肤病学 | 100篇 |
神经病学 | 292篇 |
特种医学 | 234篇 |
外科学 | 918篇 |
综合类 | 94篇 |
一般理论 | 2篇 |
预防医学 | 320篇 |
眼科学 | 185篇 |
药学 | 623篇 |
中国医学 | 49篇 |
肿瘤学 | 425篇 |
出版年
2023年 | 106篇 |
2022年 | 142篇 |
2021年 | 219篇 |
2020年 | 131篇 |
2019年 | 149篇 |
2018年 | 244篇 |
2017年 | 177篇 |
2016年 | 188篇 |
2015年 | 206篇 |
2014年 | 295篇 |
2013年 | 337篇 |
2012年 | 461篇 |
2011年 | 477篇 |
2010年 | 258篇 |
2009年 | 230篇 |
2008年 | 360篇 |
2007年 | 352篇 |
2006年 | 297篇 |
2005年 | 252篇 |
2004年 | 259篇 |
2003年 | 220篇 |
2002年 | 220篇 |
2001年 | 83篇 |
2000年 | 60篇 |
1999年 | 69篇 |
1998年 | 58篇 |
1997年 | 46篇 |
1996年 | 42篇 |
1995年 | 44篇 |
1994年 | 32篇 |
1993年 | 45篇 |
1992年 | 50篇 |
1991年 | 68篇 |
1990年 | 56篇 |
1989年 | 48篇 |
1988年 | 34篇 |
1987年 | 40篇 |
1986年 | 35篇 |
1985年 | 17篇 |
1984年 | 42篇 |
1983年 | 22篇 |
1982年 | 28篇 |
1981年 | 28篇 |
1980年 | 24篇 |
1979年 | 30篇 |
1978年 | 17篇 |
1974年 | 16篇 |
1973年 | 20篇 |
1972年 | 16篇 |
1970年 | 17篇 |
排序方式: 共有6803条查询结果,搜索用时 0 毫秒
1.
2.
Krishna K. Singh Yuxin Dong John T. Belisle Jeffrey Harder Vijay K. Arora Suman Laal 《Clinical and Vaccine Immunology : CVI》2005,12(2):354-358
Serum samples obtained from human immunodeficiency virus (HIV)-infected tuberculosis (TB) patients months prior to clinical TB were used to delineate the profile of Mycobacterium tuberculosis culture filtrate proteins recognized during subclinical TB. A subset of ~12 antigens was recognized by antibodies in these serum samples. Antibodies to two of these antigens (81 [88]-kDa malate synthase [GlcB] and MPT51) were present in serum samples obtained during incipient subclinical TB in 19 (~90%) of the 21 HIV-infected TB patients tested. These antigens will be useful for devising diagnostic tests that can identify HIV-positive individuals who are at a high risk for developing clinical TB. 相似文献
3.
A forty year old female patient developed paraesthesia of the right side of her lower lip following the placement of an extensive pin-retained amalgam restoration in her lower right second premolar tooth. Radiographs indicated that the mental foramen was close to the apex of this tooth and it was assumed that postoperative pulpitis and periapical inflammation had caused the paraesthesia through the effects of pressure on the mental nerve. The paraesthesia resolved following endodontic treatment of the lower second premolar tooth and the patient has had no further signs or symtoms. 相似文献
4.
Niteen V Deshpande Harshawardhan M Mardikar Dhananjay Deo 《Journal of the American College of Cardiology》2007,49(13):1502; author reply 1502-1502; author reply 1503
5.
6.
Valerie L. Blanco RDH MS Steven M. Levy DDS MPH Ronald L. Ettinger BDS MDS DDSc Henrietta Logan PhD Kathleen C. Buckwalter PhD RN 《Special care in dentistry》1997,17(4):129-132
Little is known about oral health care behaviors of community-dwelling, cognitively impaired elderly (CIE) persons. Few studies have been conducted regarding the actual provision of oral care for CIE persons or the attitudes and concerns about oral health among their caregivers. The CIE person's ability to perform self-care decreases over time, and the role of the caregiver in daily oral care becomes increasingly important. The purpose of this pilot study was to explore the attitudes toward oral health and identify related concerns among caregivers who care for community-dwelling CIE persons. Caregivers were surveyed by means of a self-administered, mailed questionnaire. To maintain confidentiality, an intermediary was used for recruitment and data collection. Overall, 148 caregivers were invited by an intermediary to participate in the survey; only 21 (14%) consented to participate and returned the questionnaire. This paper discusses some of the numerous methodological challenges identified when an attempt was made to survey caregivers' attitudes toward and barriers to providing oral care for a dependent CIE. 相似文献
7.
Denis O'Mullane PhD ; Helen P. Whelton PhD ; Pat Costelloe BDS David Clarke BDS ; Stephen McDermott MSc ; Jacinta McLoughlin MDS 《Journal of public health dentistry》1996,56(5):259-264
The visit of Dr. Trendley Dean to Dublin in the mid-1950s helped accelerate the decision to introduce water fluoridation as a public health measure in the prevention of caries in the Republic of Ireland. A challenge to the constitutional validity of the Health (Fluoridation of Water Supplies) Act 1960 failed and in 1964 the water supplies of Dublin city were fluoridated. Over the next seven to eight years all the major urban communities in the Republic of Ireland were fluoridated. Currently, 67 percent of the 3.5 million people in the country reside in fluoridated communities. Studies conducted over the last 20 years show that residents of fluoridated communities have better dental health than those in nonfluoridated communities—the mean dmft is lower in children and the number of natural teeth present in adults is higher. 相似文献
8.
Extra-amniotic ethacridine lactate plus intramuscular prostaglandin has become a popular method for terminating second trimester pregnancies. In this study, intrauterine pressure was continuously monitored in order to objectively compare the efficacy of 3 different times of administration of Carboprost (15-methyl PGF2alpha)-at 2 hours, 4 hours and 8 hours after the instillation of ethacridine lactate. The best results were obtained with the administration of Carboprost 8 hours after the instillation of the extra-amniotic ethacridine lactate. The synergistic effect of ethacridine lactate and Carboprost is optimal after this time. This is probably because the ethacridine lactate will have produced sufficient cervical ripening to ensure optimal efficacy of the prostaglandin-induced uterine contractions in expelling the products of conception.
Resumen Un método popular para terminar un embarazo en el segundo trimestre es el lactato de etacridina extraamniótico más prostaglandina intramuscular. En este estudio la presión intrauterina estuvo registrada continuamente a fin de comparar objetivamente la eficacia a 3 horarios diferentes de administración de Carboprost (15-metilo PGF2alpha) a las 2 horas, 4 horas y 8 horas después de la instilación de lactato de etacridina. Los mejores resultados fueron obtenidos con la administración de Carboprost 8 horas después de la instilación extraamniótica de lactato de etacridina. Después de este tiempo el efecto sinergístico del lactato de etacridina y Carboprost es óptimo. Probablemente esto se debe a que el lactato de etacridina ha producido ablandamiento cervical suficiente para asegurar la óptima eficacia de las contracciones uterinas inducidas por la prostaglandina para eliminar los productos de la concepción.
Résumé L'administration associée de lactate d'éthacridine extra-amniotique et de prostaglandine intramusculaire est devenue une méthode courante d'interruption de grossesses au deuxième trimestre. Au cours de cette étude, la pression intra-utérine a été contrôlée en continu afin de pouvoir comparer objectivement l'efficacité à trois moments différents d'administration de Carboprost (15-méthyle PGF2alpha): 2 heures, 4 heures et 8 heures après l'instillation de lactate d'éthacridine. Les meilleurs résultats one été obtenus lorsque le Carboprost a été administré 8 heures après l'instillation de lactate d'éthacridine extra-amniotique. L'effet conjugué du lactate d'éthacridine et du Carboprost est optimal après ce délai, sans doute parce que le lactate d'éthacridine aura permis alors une maturation cervicale suffisante pour assurer une efficacité optimale aux contractions utérines provoquées par la prostaglandine en vue de l'expulsion des produits de conception.相似文献
9.
10.
Retinoblastoma. A clinical, immunohistochemical, and electron microscopic case report 总被引:2,自引:0,他引:2
A 4-year, 9-month-old boy had a history of leukocoria of the right eye for approximately six months prior to admission. The other eye was normal. There was no family history of retinoblastoma. Funduscopy disclosed a large white mass extending from the nasal pars plana to the mid-pupillary zone and the posterior pole with a near total retinal detachment in the superior temporal quadrant. A B-scan ultrasound showed an echo dense area of the anterior portion of the mass. A CT scan showed intraocular tissue densities with no evidence of optic nerve involvement or extraocular extension. Immunohistochemistry of a fresh frozen portion of tumor revealed reactivity with antibodies directed against interphotoreceptor retinoid-binding-protein (IRBP), neuron-specific enolase, glial fibrillary acidic protein, S-antigen, focal reactivity with opsin, and scattered cytoplasmic staining for cyclic GMP and cyclic GMP phosphodiesterase. Biochemical analysis of fresh frozen tissue samples confirmed the presence of IRBP. Transmission electron microscopy disclosed occasional Flexner-Wintersteiner rosettes connected by zonula adherens-like junctions. These showed inner segment-like structures containing prominent mitochondria, portions of cilia and fragments of outer segment material. These data, along with the immunocytochemistry indicates a predominant neuronal nature of the tumor cells with significant photoreceptor-like differentiation. 相似文献